Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Balbino Alarcon"'
Autor:
Nuria Martinez-Martin, Balbino Alarcon
Publikováno v:
Biomedical Journal, Vol 47, Iss 5, Pp 100630- (2024)
Trogocytosis is an active process whereby fragments of plasma membrane proteins and cytoplasm are transferred from one cell to another in a cell-cell contact-dependent manner. T cells trogocytose pieces of the cells presenting antigen to them at the
Externí odkaz:
https://doaj.org/article/a60d7f438c73495ca242a686d91186e0
Autor:
Patricia Almendro-Vázquez, Rocio Laguna-Goya, Maria Ruiz-Ruigomez, Alberto Utrero-Rico, Antonio Lalueza, Guillermo Maestro de la Calle, Pilar Delgado, Luis Perez-Ordoño, Eva Muro, Juan Vila, Isabel Zamarron, Miguel Moreno-Batanero, Marta Chivite-Lacaba, Francisco Javier Gil-Etayo, Carmen Martín-Higuera, María Ángeles Meléndez-Carmona, Carlos Lumbreras, Irene Arellano, Balbino Alarcon, Luis Miguel Allende, Jose Maria Aguado, Estela Paz-Artal
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010211 (2021)
The timing of the development of specific adaptive immunity after natural SARS-CoV-2 infection, and its relevance in clinical outcome, has not been characterized in depth. Description of the long-term maintenance of both cellular and humoral response
Externí odkaz:
https://doaj.org/article/043a5faafb7f45a1a8272beb17c4ccfa
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/6e4e7931fc5e4fe8bb3d1098435297a4
Autor:
Nicla Porciello, Paola Grazioli, Antonio F. Campese, Martina Kunkl, Silvana Caristi, Marta Mastrogiovanni, Michela Muscolini, Francesca Spadaro, Cédric Favre, Jacques A. Nunès, Aldo Borroto, Balbino Alarcon, Isabella Screpanti, Loretta Tuosto
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
CD28 transmits co-stimulatory signals for the activation of both mouse and human T cells, but in vivo hyperactivation of CD28 has opposite effects on system immunity. Here, the authors show that a single amino acid difference between mouse and human
Externí odkaz:
https://doaj.org/article/e98ff31ccbfc47539c572574b4d9cb31
Autor:
Claudia Cifuentes, Clara L. Oeste, Isabel Fernández-Pisonero, Alejandro M. Hortal, Carmen García-Macías, Jeanne Hochart, Regina Rubira, Lydia Horndler, Carlos Horndler, Xosé R. Bustelo, Balbino Alarcón
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-28 (2024)
Abstract Background Breast cancer (BC) is the most common cancer in women, with triple negative BC (TNBC) accounting for 20% of cases. While early detection and targeted therapies have improved overall life expectancy, TNBC remains resistant to curre
Externí odkaz:
https://doaj.org/article/50bafe4d36984ae5843b8ab7cb2b0b97
Publikováno v:
Transplantation and Cellular Therapy. 28:S283-S284
Autor:
Hien T. Huynh, Chandrashekara Mahadevappa Puthanapura, Alfreda D Nelson, Laura RE Becher, Megan Abergel, Shuang Hu, Balbino Alarcon, Adam Schrum, Diana Gil Pages
Publikováno v:
The Journal of Immunology. 208:122.16-122.16
A cognate antigen engagement of TCR induces a conformational change in the CD3 complex (CD3Δc) that is required for productive T cell activation. CD3Δc fails when TCRs interact with poorly immunogenic antigens that do not active T cells. Anti-CD3 m
Autor:
Clara L. Oeste, Cristina Prieto, Viola L. Boccasavia, Diego Alonso-López, Facundo D. Batista, Manuel D. Díaz-Muñoz, Elena R. Bovolenta, Aldo Borroto, Balbino Alarcon
Publikováno v:
SSRN Electronic Journal.
T cells form immunological synapses with professional antigen presenting cells (APCs) resulting not only in T cell activation but also in the acquisition of peptide antigen-MHC (pMHC) complexes from the plasma membrane of the APC becoming APCs themse
Autor:
Ana V. Marin, Rebeca F. Megino, Marcos Viñuela, Olga Popova, Irene Real-Arevalo, Jose L. Sanchez-Majano, Pablo L. Ortiz-Romero, Maria J. Castro-Panete, Esther Mancebo, Paloma Talayero, Estela Paz-Artal, Maria L. Paciello, Joaquin Martinez-Lopez, Jose L. Subiza, Pedro A. Reche, Nuria Lopez-Bigas, Miguel Marcilla, Alberto Paradela, Manuel Gomez del Moral, Eduardo Martinez-Naves, Alvaro Serrano, Ester Marina-Zarate, Almudena R. Ramiro, Pablo Engel, Mercedes Dominguez, Inmaculada Moreno, Isabel Cortegano, Belen de Andres, Maria L. Gaspar, Marina Garcia-Peydro, Antonio Balas, Miguel A. Moreno, Raquel Alenda, Jose L. Vicario, Immanuel F. Luescher, Maria L. Toribio, Balbino Alarcon, Jose R. Regueiro
Publikováno v:
The Journal of Immunology. 206:67.20-67.20
Sézary syndrome (SS) is a leukemic form of cutaneous mature T-cell lymphoma characterized by circulating malignant CD4 T lymphocytes (Sezary cells). Patients with SS have a poor prognosis and current treatment options show high rates of relapse, mor
Autor:
Balbino Alarcon, Andres Gagete, Diana Reyes-Garau, Shannon C Dwyer, Chris VanDeusen, Aldo Borroto
Publikováno v:
Transplantation and Cellular Therapy. 27:S253