Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Balazs Banfai"'
Autor:
Manaswini Sivaramakrishnan, Kathleen D. McCarthy, Sébastien Campagne, Sylwia Huber, Sonja Meier, Angélique Augustin, Tobias Heckel, Hélène Meistermann, Melanie N. Hug, Pascale Birrer, Ahmed Moursy, Sarah Khawaja, Roland Schmucki, Nikos Berntenis, Nicolas Giroud, Sabrina Golling, Manuel Tzouros, Balazs Banfai, Gonzalo Duran-Pacheco, Jens Lamerz, Ying Hsiu Liu, Thomas Luebbers, Hasane Ratni, Martin Ebeling, Antoine Cléry, Sergey Paushkin, Adrian R. Krainer, Frédéric H.-T. Allain, Friedrich Metzger
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Small molecules correcting the splicing deficit of the survival of motor neuron 2 (SMN2) gene have been identified as having therapeutic potential. Here, the authors provide evidence that SMN2 mRNA forms a ribonucleoprotein complex that can be specif
Externí odkaz:
https://doaj.org/article/86ed63c63e664f938352b802e813bfcc
Autor:
Ting Huang, Meena Choi, Sabrina Golling, Nikhil J. Pandya, Manuel Tzouros, Balazs Banfai, Olga Vitek, Tom Dunkley
Publikováno v:
Molecular & Cellular Proteomics : MCP
MSstatsTMT implements a general statistical approach for relative protein quantification and tests for differential abundance in mass spectrometry-based experiments with TMT labeling. It is applicable to experiments with multiple conditions, multiple
Autor:
Leonard D. Goldstein, Filip Roudnicky, Bo Kyoung Kim, Claas A. Meyer, Lisa Sach-Peltason, Nikhil J. Pandya, Klaus Christensen, Christoph Patsch, Héloïse Ragelle, Oliv Eidam, Chad A. Cowan, Martin Graf, Pamela Strassburger, Zora Modrusan, Mark Burcin, Balazs Banfai, Verena Kueppers, Manuel Tzouros, Mirjana Lazendic, Sabine Uhles, Gregor Sturm, Peter D. Westenskow, Franco Revelant, Yanjun Lan, Jitao David Zhang, Sabine Gruener
Publikováno v:
Proc Natl Acad Sci U S A
The blood–retina barrier and blood–brain barrier (BRB/BBB) are selective and semipermeable and are critical for supporting and protecting central nervous system (CNS)-resident cells. Endothelial cells (ECs) within the BRB/BBB are tightly coupled,
Autor:
Tony Kam-Thong, Fabian Birzele, Lucy Hutchinson, Balazs Banfai, Bernhard Steiert, Solveig Badillo, Jitao David Zhang, Juliane Siebourg-Polster, Iakov I. Davydov
Publikováno v:
Clinical Pharmacology and Therapeutics
In the last few years, machine learning (ML) and artificial intelligence have seen a new wave of publicity fueled by the huge and ever-increasing amount of data and computational power as well as the discovery of improved learning algorithms. However
Autor:
Paul Lopatta, Ravi Jagasia, Rasmussen Søren Vestergaard, Tom Dunkley, Marco Berrera, Nikhil J. Pandya, Edwin Mientjes, Tania Distler, Ben Distel, Balazs Banfai, F. Isabella Zampeta, Ype Elgersma, Philip Grossen, Christoph Patsch, Martin Ebeling, Thomas Kremer, Sonja Meier, Yasmina Martí, A. Mattijs Punt, Congwei Wang, Veronica Costa, Manuel Tzouros, Marius C. Hoener
Publikováno v:
Cell Reports Medicine
Cell Reports Medicine, 2(8):100360. Cell Press
Cell Reports Medicine, 2(8):100360. Cell Press
Angelman syndrome (AS) is a neurodevelopmental disorder caused by the loss of maternal UBE3A, a ubiquitin protein ligase E3A. Here, we study neurons derived from patients with AS and neurotypical individuals, and reciprocally modulate UBE3A using ant
Autor:
Olga Vitek, Tom Dunkley, Meena Choi, Tsung-Heng Tsai, Brendan MacLean, Balazs Banfai, Yansheng Liu
Publikováno v:
Mol Cell Proteomics
In bottom-up mass spectrometry-based proteomics, relative protein quantification is often achieved with data-dependent acquisition (DDA), data-independent acquisition (DIA), or selected reaction monitoring (SRM). These workflows quantify proteins by
Autor:
Paula M. Petrone, Roberto Iacone, Esther Melo, Peter Jakob, Corinne Stucki, Chia-yi Chen, Oliver Schilling, Frederic Delobel, Doris Roth, Alvaro Cortes Cabrera, Balazs Banfai, Andreas Topp, Sylwia Huber, Tom Dunkley
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
The human protease family HtrA is responsible for preventing protein misfolding and mislocalization, and a key player in several cellular processes. Among these, HtrA1 is implicated in several cancers, cerebrovascular disease and age-related macular
Autor:
Hasane Ratni, Jens Lamerz, Kathleen D. McCarthy, Martin Ebeling, Hélène Meistermann, Pascale Birrer, Frédéric H.-T. Allain, Roland Schmucki, Friedrich Metzger, Gonzalo Duran-Pacheco, Sonja Meier, Sarah Khawaja, Manuel Tzouros, Angélique Augustin, Sergey Paushkin, Sébastien Campagne, Antoine Cléry, Melanie N. Hug, Thomas Luebbers, Nikos Berntenis, Manaswini Sivaramakrishnan, Sylwia Huber, Ahmed Moursy, Balazs Banfai, Nicolas Giroud, Ying Hsiu Liu, Adrian R. Krainer, Sabrina Golling, Tobias Heckel
Publikováno v:
Nature Communications
Nature Communications, 8 (1)
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications, 8 (1)
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Small molecule splicing modifiers have been previously described that target the general splicing machinery and thus have low specificity for individual genes. Several potent molecules correcting the splicing deficit of the SMN2 (survival of motor ne
Autor:
Balazs Banfai, Francois Christen, Michael Winter, Barbara Lenz, Moritz Bennecke, Pierre Maliver, Matthias Festag
Publikováno v:
Toxicologic pathology. 45(4)
Clofibrate is a known rodent hepatotoxicant classically associated with hepatocellular hypertrophy and increased serum activities of cellular alanine aminotransferase/aspartate aminotransferase (ALT/AST) in the absence of microscopic hepatocellular d
Autor:
Balazs Banfai, Sándor Kemény
Publikováno v:
Journal of Chemometrics. 26:117-124
The applicability of single-point calibration is usually decided by testing the hypothesis of zero intercept. It is flawed, first, because the zero intercept does not infer that it is true, and second, accepting a zero intercept does not imply a low