Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Balazs Csernus"'
Autor:
Chunyan Yang, Balazs Csernus, Amy Chadburn, Elizabeth Hyjek, Y. Lynn Wang, Yifang Liu, Seung-Hee Jo
Publikováno v:
The American Journal of Pathology. 170:722-732
Peroxisome proliferator-activated receptor gamma (PPARgamma) is a metabolic regulator involved in maintaining glucose and fatty acid homeostasis. Besides its metabolic functions, the receptor has also been implicated in tumorigenesis. Ligands of PPAR
Publikováno v:
The Journal of Molecular Diagnostics. 8:231-239
Monitoring breakpoint cluster region-Abelson kinase (BCR-ABL) levels in patients treated for chronic myelogenous leukemia (CML) has become an integral part of patient management. Real-time reverse transcriptase- polymerase chain reaction is the metho
Publikováno v:
Journal of Molecular Neuroscience. 21:173-184
Tumor necrosis factor (TNF-alpha) is involved in the inflammation and tissue regeneration occurring after spinal cord injury (SCI). This study tests the specific role of p55 and p75 receptors in mediating the transport of TNF-alpha across the blood-s
Publikováno v:
Journal of Neuroendocrinology. 14:5-13
A cytotoxic analogue of LH-RH, AN-207, consisting of 2-pyrrolinodoxorubicin (AN-201) linked to carrier [D-Lys6]LH-RH, was developed for targeted therapy of cancers expressing LH-RH-receptors. To determine its possible side-effects on the pituitary gl
Autor:
Amy Chadburn, Ethel Cesarman, Peter Martin, Darya Bubman, Balazs Csernus, Daniel M. Knowles, Elizabeth Hyjek, David R. Czuchlewski
Publikováno v:
American journal of clinical pathology. 130(6)
Sphingolipids serve an important role as effector molecules in signaling pathways bearing on apoptosis and cell survival. The balance between proapoptotic ceramide and prosurvival sphingosine-1-phosphate, sometimes termed the “sphingolipid rheostat
Publikováno v:
Journal of neuroimmunology. 134(1-2)
We generated a novel mouse model of spinal cord injury (SCI) by hemisection of the right L1 lumbar spinal cord, measured the permeability of the blood-spinal cord barrier (BSCB), and tested the hypothesis that tumor necrosis factor alpha (TNF alpha)
Autor:
Balazs Csernus, Jozsef L. Varga, Tamas Czompoly, Andrew V. Schally, Artur Plonowski, Zoltan Rekasi
Publikováno v:
The Prostate. 48(3)
Background Prostate-specific antigen (PSA) is the best tumor marker for diagnosis and prognosis of prostatic carcinoma. The secretion of PSA from LNCaP human prostate cancer cells is influenced by acute stimuli such as vasoactive intestinal peptide (
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 98(4)
The mechanisms through which LH-RH antagonists suppress gonadotroph functions and LH-RH receptor (LH-RH-R) production are incompletely understood. To elucidate these mechanisms, we investigated the effects of Cetrorelix on the mRNA expression of pitu
Autor:
Gabor Halmos, Andrew V. Schally, Jozsef L. Varga, Kate Groot, Patricia Armatis, Balazs Csernus, Zoltan Rekasi, Artur Plonowski
We evaluated the effects of GHRH antagonists on the proliferation of MiaPaCa-2 human pancreatic cancer cells and cAMP signaling in vitro. GHRH antagonists inhibited the proliferation of MiaPaCa-2 cells in vitro in a dose-dependent way and caused a si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbacf6a41f24397e744fe8319563793
Publikováno v:
Blood. 106:992-992
Reactive Oxygen Species (ROS) act as second messengers in various cellular signaling cascades. While high levels of ROS induce oxidative stress response and cause cell death, lower levels of ROS in cancer cells can actually promote neoplastic growth