Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Balazs, Siminszky"'
Publikováno v:
Journal of Biological Chemistry. 287:42804-42811
Nicotine and its N-demethylation product nornicotine are two important alkaloids in Nicotiana tabacum L. (tobacco). Both nicotine and nornicotine have two stereoisomers that differ from each other at 2'-C position on the pyrrolidine ring. (S)-Nicotin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b52c43ab0af7fd53150ebdaf78f617
https://doi.org/10.1074/jbc.m112.413807
https://doi.org/10.1074/jbc.m112.413807
Autor:
Vincent J. M. Robert, Lowell P. Bush, Ralph E. Dewey, Balazs Siminszky, Ramsey S. Lewis, Anne M. Jack, Jerry Whit Morris, Alec J. Hayes, Lily Gavilano
Publikováno v:
Plant Biotechnology Journal. 6:346-354
Technologies for reducing the levels of tobacco product constituents that may contribute to unwanted health effects are desired. Target compounds include tobacco-specific nitrosamines (TSNAs), a class of compounds generated through the nitrosation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44cb46279e4c5a292e7c4497e20edfe9
https://doi.org/10.1111/j.1467-7652.2008.00324.x
https://doi.org/10.1111/j.1467-7652.2008.00324.x
Autor:
Balazs Siminszky, Ralph E. Dewey, Nicholas P. Coleman, Manohar Chakrabarti, Steven W. Bowen, Karen M. Meekins
Publikováno v:
Plant Molecular Biology. 66:415-427
Nicotine to nornicotine conversion in tobacco (Nicotiana tabacum L.) is regulated by an unstable converter locus which in its activated state gives rise to a high nornicotine, low nicotine phenotype in the senescing leaves. In plants that carry the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebb1ed248e237797decb1505f16d8ed
https://doi.org/10.1007/s11103-007-9280-6
https://doi.org/10.1007/s11103-007-9280-6
Autor:
Lily Gavilano, Balazs Siminszky
Publikováno v:
Plant and Cell Physiology. 48:1567-1574
In the species of genus Nicotiana, nicotine to nornicotine conversion is mediated by closely related nicotine N-demethylase (NND) proteins that are encoded by the CYP82E subfamily of cytochrome P450 genes. The diverse number and transcriptional regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058351b63c96bb43715ac32ae89d76ad
https://doi.org/10.1093/pcp/pcm128
https://doi.org/10.1093/pcp/pcm128
Publikováno v:
New Phytologist. 175:565-574
Summary • The alkaloid profile of cultivated tobacco (Nicotiana tabacum) is different from that of its two progenitors, Nicotiana sylvestris and Nicotiana tomentosiformis, in that tobacco accumulates nicotine as the most abundant alkaloid, while it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d91bce9bed44c97957b8beab2417bf
https://doi.org/10.1111/j.1469-8137.2007.02116.x
https://doi.org/10.1111/j.1469-8137.2007.02116.x
Publikováno v:
Journal of Biological Chemistry. 282:249-256
Tobacco (Nicotiana tabacum L.) is a natural allotetraploid derived from the interspecific hybridization between ancestral Nicotiana sylvestris and Nicotiana tomentosiformis. The majority of cultivated tobacco differs from both of its progenitor speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d81018700cb80809e59acc9c6cbe90
https://doi.org/10.1074/jbc.m609512200
https://doi.org/10.1074/jbc.m609512200
Autor:
Balazs Siminszky
Publikováno v:
Phytochemistry Reviews. 5:445-458
In the last two decades it has become apparent that enzymes of the P450 monooxygenase (P450) superfamily are responsible for the Phase I metabolism of numerous herbicides representing several classes of organic compounds. The majority of experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c3b224e3ca6898e05b65953e854d43a
https://doi.org/10.1007/s11101-006-9011-7
https://doi.org/10.1007/s11101-006-9011-7
Publikováno v:
Weed Science. 53:146-152
Acetolactate synthase (ALS), a common enzyme in the biosynthesis of branched-chain amino acids, is a target for the sulfonylurea, imidazolinone, triazolopyrimidine, pyrimidinylthiobenzoate, and the sulfonylaminocarbonyltriazolinone classes of herbici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abad503bca3cc621c24ec50b7d88496a
https://doi.org/10.1614/ws-04-132r
https://doi.org/10.1614/ws-04-132r
Co-expression of a NADPH:P450 reductase enhances CYP71A10-dependent phenylurea metabolism in tobacco
Publikováno v:
Pesticide Biochemistry and Physiology. 77:35-43
A soybean cytochrome P450 monooxygenase, designated CYP71A10, catalyzes the oxidative N-demethylation or ring methyl hydroxylation of a variety of phenylurea herbicides. The ectopic expression of CYP71A10 in tobacco was previously shown to be an effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76b53f7746488939813c4fb0367f2549
https://doi.org/10.1016/j.pestbp.2003.08.001
https://doi.org/10.1016/j.pestbp.2003.08.001
Publikováno v:
Weed Science. 48:291-295
The isolation of a Glycine max cytochrome P450 monooxygenase (P450) cDNA designated CYP71A10 that conferred linuron resistance to laboratory-grown, transgenic Nicotiana tabacum seedlings was previously reported. A nonsegregating transgenic N. tabacum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::389b6974373ae001af368ec587e86a30
https://doi.org/10.1614/0043-1745(2000)048[0291:acpmcc]2.0.co
https://doi.org/10.1614/0043-1745(2000)048[0291:acpmcc]2.0.co