Zobrazeno 1 - 10
of 368
pro vyhledávání: '"Balazs, Dome"'
Autor:
Karin Schelch, Sebastian Eder, Benjamin Zitta, Monica Phimmachanh, Thomas G. Johnson, Dominik Emminger, Andrea Wenninger‐Weinzierl, Caterina Sturtzel, Hugo Poplimont, Alexander Ries, Konrad Hoetzenecker, Mir A. Hoda, Walter Berger, Martin Distel, Balazs Dome, Glen Reid, Michael Grusch
Publikováno v:
Molecular Oncology, Vol 18, Iss 4, Pp 815-831 (2024)
Pleural mesothelioma (PM) is characterized by rapid growth, local invasion, and limited therapeutic options. The multifunctional oncoprotein Y‐box‐binding protein‐1 (YB‐1) is frequently overexpressed in cancer and its inhibition reduces aggre
Externí odkaz:
https://doaj.org/article/0fdbc05b2f2540f8bfe43842f519eeb5
Autor:
Christian Lang, Zsolt Megyesfalvi, Andras Lantos, Felicitas Oberndorfer, Mir Alireza Hoda, Anna Solta, Bence Ferencz, Janos Fillinger, Anna Solyom-Tisza, Alessandro Saeed Querner, Felix Egger, Kristiina Boettiger, Thomas Klikovits, Gerald Timelthaler, Ferenc Renyi-Vamos, Clemens Aigner, Konrad Hoetzenecker, Viktoria Laszlo, Karin Schelch, Balazs Dome
Publikováno v:
World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background By being highly involved in the tumor evolution and disease progression of small cell lung cancer (SCLC), Myc family members (C-Myc, L-Myc, and N-Myc) might represent promising targetable molecules. Our aim was to investigate the
Externí odkaz:
https://doaj.org/article/234161e89df04bc49487dd2d775855f8
Autor:
Berta Mosleh, Karin Schelch, Thomas Mohr, Thomas Klikovits, Christina Wagner, Lukas Ratzinger, Yawen Dong, Katharina Sinn, Alexander Ries, Walter Berger, Bettina Grasl‐Kraupp, Konrad Hoetzenecker, Viktoria Laszlo, Balazs Dome, Balazs Hegedus, Marko Jakopovic, Mir Alireza Hoda, Michael Grusch
Publikováno v:
Thoracic Cancer, Vol 14, Iss 22, Pp 2177-2186 (2023)
Abstract Background Pleural mesothelioma (PM) is a relatively rare malignancy with limited treatment options and dismal prognosis. We have previously found elevated FGF18 expression in PM tissue specimens compared with normal mesothelium. The objecti
Externí odkaz:
https://doaj.org/article/280b1a46403a482d865fcc37356d2cba
Autor:
David Dora, Balazs Ligeti, Tamas Kovacs, Peter Revisnyei, Gabriella Galffy, Edit Dulka, Dániel Krizsán, Regina Kalcsevszki, Zsolt Megyesfalvi, Balazs Dome, Glen J. Weiss, Zoltan Lohinai
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTDue to the high variance in response rates concerning anti-PD1 immunotherapy (IT), there is an unmet need to discover innovative biomarkers to predict immune checkpoint inhibitor (ICI)-efficacy. Our study included 62 Caucasian advanced-stage
Externí odkaz:
https://doaj.org/article/3192af9b75d0451fa3c5111eb3db9471
Autor:
Bastian Seelbinder, Zoltan Lohinai, Ruben Vazquez-Uribe, Sascha Brunke, Xiuqiang Chen, Mohammad Mirhakkak, Silvia Lopez-Escalera, Balazs Dome, Zsolt Megyesfalvi, Judit Berta, Gabriella Galffy, Edit Dulka, Anja Wellejus, Glen J. Weiss, Michael Bauer, Bernhard Hube, Morten O. A. Sommer, Gianni Panagiotou
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Candida species overgrowth in the human gut is considered a prerequisite for invasive candidiasis, but our understanding of gut bacteria promoting or restricting this overgrowth is still limited. By integrating cross-sectional mycobiome and
Externí odkaz:
https://doaj.org/article/995d19354eac486bafefacd3d3f6112b
Autor:
Alexander Ries, Daniela Flehberger, Astrid Slany, Christine Pirker, Johanna C. Mader, Thomas Mohr, Karin Schelch, Katharina Sinn, Berta Mosleh, Mir Alireza Hoda, Balazs Dome, Helmut Dolznig, Georg Krupitza, Leonhard Müllauer, Christopher Gerner, Walter Berger, Michael Grusch
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-20 (2023)
Abstract Background Pleural mesothelioma (PM) is an aggressive malignancy with poor prognosis. Unlike many other cancers, PM is mostly characterized by inactivation of tumor suppressor genes. Its highly malignant nature in absence of tumor driving on
Externí odkaz:
https://doaj.org/article/0584feb1baa7455e98b30e32f6b10aef
Autor:
Marton Gyulai, Zsolt Megyesfalvi, Lilla Reiniger, Tunde Harko, Bence Ferencz, Luca Karsko, Laszlo Agocs, Janos Fillinger, Balazs Dome, Zoltan Szallasi, Judit Moldvay
Publikováno v:
Pathology and Oncology Research, Vol 29 (2023)
Background: Our knowledge is still limited about the characteristics and treatment of rare lung tumors. The aim of our study was to determine programmed cell death ligand-1 (PD-L1) and programmed cell death-1 (PD-1) expression in rare pulmonary tumor
Externí odkaz:
https://doaj.org/article/b9f0cf08651e45688c8a7f1f5ad9ab72
Autor:
Alexander Ries, Astrid Slany, Christine Pirker, Johanna C. Mader, Doris Mejri, Thomas Mohr, Karin Schelch, Daniela Flehberger, Nadine Maach, Muhammad Hashim, Mir Alireza Hoda, Balazs Dome, Georg Krupitza, Walter Berger, Christopher Gerner, Klaus Holzmann, Michael Grusch
Publikováno v:
Cells, Vol 12, Iss 15, p 2006 (2023)
Pleural mesothelioma (PM) is an aggressive malignancy that develops in a unique tumor microenvironment (TME). However, cell models for studying the TME in PM are still limited. Here, we have generated and characterized novel human telomerase reverse
Externí odkaz:
https://doaj.org/article/8865651d49ae4f9aa0376956496bb9c2
Autor:
Anna Schwendenwein, Zsolt Megyesfalvi, Nandor Barany, Zsuzsanna Valko, Edina Bugyik, Christian Lang, Bence Ferencz, Sandor Paku, Andras Lantos, Janos Fillinger, Melinda Rezeli, Gyorgy Marko-Varga, Krisztina Bogos, Gabriella Galffy, Ferenc Renyi-Vamos, Mir Alireza Hoda, Walter Klepetko, Konrad Hoetzenecker, Viktoria Laszlo, Balazs Dome
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss , Pp 470-483 (2021)
Small cell lung cancer (SCLC; accounting for approximately 13%–15% of all lung cancers) is an exceptionally lethal malignancy characterized by rapid doubling time and high propensity to metastasize. In contrast to the increasingly personalized ther
Externí odkaz:
https://doaj.org/article/88d8695340f84189ac9c8682d2e28c37
Autor:
Zsolt Megyesfalvi, Bernadett Tallosy, Orsolya Pipek, Janos Fillinger, Christian Lang, Thomas Klikovits, Anna Schwendenwein, Mir Alireza Hoda, Ferenc Renyi‐Vamos, Viktoria Laszlo, Melinda Rezeli, Judit Moldvay, Balazs Dome
Publikováno v:
Thoracic Cancer, Vol 12, Iss 6, Pp 914-923 (2021)
Abstract Background Early metastasis is a hallmark of small cell lung cancer (SCLC). However, the mechanisms and resulting patterns of SCLC dissemination are unclear. Our aim was thus to investigate the organ specificity and timing of blood‐borne m
Externí odkaz:
https://doaj.org/article/7679c7f58f2b4212b339e429249b995f