Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Balasubramanian, Manickam"'
Autor:
Teresa Hauguel, Amy Sharma, Emily Mastrocola, Susan Lowry, Mohan S. Maddur, Cheng Hui Hu, Swati Rajput, Allison Vitsky, Shambhunath Choudhary, Balasubramanian Manickam, Ivna De Souza, Yana Chervona, Raquel Munoz Moreno, Charisse Abdon, Larissa Falcao, Kristin Tompkins, Deanne Illenberger, Rachel Smith, Fanyu Meng, Shuai Shi, Kari Sweeney Efferen, Victoria Markiewicz, Cinthia Umemoto, Jianfang Hu, Wei Chen, Ingrid Scully, Cynthia M. Rohde, Annaliesa S. Anderson, Pirada Suphaphiphat Allen
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Seasonal epidemics of influenza viruses are responsible for a significant global public health burden. Vaccination remains the most effective way to prevent infection; however, due to the persistence of antigenic drift, vaccines must be upda
Externí odkaz:
https://doaj.org/article/4607329bb3c94f76a3e2582ec9702cb5
Autor:
Devan, Ponnusamy Kumarasami1 (AUTHOR), Balasubramanian, Manickam1 (AUTHOR) manianmb@gmail.com
Publikováno v:
Environmental Quality Management. Dec2024, Vol. 34 Issue 2, p1-10. 10p.
Autor:
Cheryl Tyszkiewicz, Seo-Kyoung Hwang, Balasubramanian Manickam, Ben Jakubczak, Karen M. Walters, Michael W. Bolt, Rosemary Santos, Chang-Ning Liu
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Introduction: Wistar Han rats are a preferred strain of rodents for general toxicology and safety pharmacology studies in drug development. In some of these studies, visual functional tests that assess for retinal toxicity are included as an addition
Externí odkaz:
https://doaj.org/article/f25de9c4ba6d4574845ae37ac0e8d073
Autor:
Balasubramanian, Manickam1 (AUTHOR), Chadalavada, Hemadri1 (AUTHOR), Madhu, Sundaram2 (AUTHOR) mathumarine@gmail.com, Naveen, Subbaiyan2 (AUTHOR)
Publikováno v:
Environmental Quality Management. Dec2023, Vol. 33 Issue 2, p185-191. 7p.
Autor:
Balasubramanian, Manickam1 (AUTHOR), Devan, Ponnusami Kumarasami1 (AUTHOR), Chadalavada, Hemadri1 (AUTHOR), Madhu, Sundaram2 (AUTHOR) mathumarine@gmail.com, Naveen, Subbaiyan2 (AUTHOR)
Publikováno v:
Environmental Quality Management. Dec2023, Vol. 33 Issue 2, p177-184. 8p.
Autor:
Caroline B Winn, Seo-Kyoung Hwang, Jeffrey Morin, Crystal T Bluette, Balasubramanian Manickam, Ziyue K Jiang, Anand Giddabasappa, Chang-Ning Liu, Kristin Matthews
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257694 (2021)
In oncology research, while xenograft tumor models are easily visualized and humane endpoints can be clearly defined, metastatic tumor models are often based on more subjective clinical observations as endpoints. This study aimed at identifying objec
Externí odkaz:
https://doaj.org/article/ffeb8f26e92e49e0b6b88f71e8149d0f
Autor:
Michael S. Thibodeau, Manoj Bhaskaran, Aleksandra Zalewska, Balasubramanian Manickam, Justin D. Vidal, Jonathan Werner, Wendy G. Halpern, Karyn Colman, Sean McKeag, Benjamin Sefing, Darren Fegley, Karen S. Regan, Binod Jacob, Eveline de Rijk, Vimala Vemireddi, George A. Parker, Hitoshi Kandori
Publikováno v:
Toxicologic Pathology. 49:977-989
The sexual maturity status of animals in nonclinical safety studies can have a significant impact on the microscopic assessment of the reproductive system, the interpretation of potential test article–related findings, and ultimately the assessment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b875dc51afa16eb8629752f0d10e9768
https://doi.org/10.1177/0192623321990631
https://doi.org/10.1177/0192623321990631
Autor:
Jean G. Sathish, Siddhartha Bhatt, Jamie K. DaSilva, Declan Flynn, Stephen Jenkinson, Amit S. Kalgutkar, Maggie Liu, Balasubramanian Manickam, Jason Pinkstaff, William J. Reagan, Norimitsu Shirai, Ahmed M. Shoieb, Madhu Sirivelu, Saurabh Vispute, Allison Vitsky, Karen Walters, Todd A. Wisialowski, Lawrence W. Updyke
Publikováno v:
International journal of toxicology. 41(4)
COVID-19 is a potentially fatal infection caused by the SARS-CoV-2 virus. The SARS-CoV-2 3CL protease (Mpro) is a viral enzyme essential for replication and is the target for nirmatrelvir. Paxlovid (nirmatrelvir co-administered with the pharmacokinet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea1a7a89320457f06d9cf5a899cc71f
https://pubmed.ncbi.nlm.nih.gov/35603517
https://pubmed.ncbi.nlm.nih.gov/35603517
Autor:
Justin D. Vidal, Manoj Bhaskaran, Mary Carsillo, Steve Denham, Olivia Dubay, Steven Laing, Balasubramanian Manickam, Stephanie Phillips, Jonathan Werner, Armando R. Irizarry Rovira
Publikováno v:
Toxicologic pathology. 50(5)
Sexually mature nonhuman primates are often used in nonclinical safety testing when evaluating biopharmaceuticals; however, there is limited information in historical control databases or in the published literature on the spontaneous findings in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9d50d34930dbf3e65a934b50c93c78
https://pubmed.ncbi.nlm.nih.gov/35285336
https://pubmed.ncbi.nlm.nih.gov/35285336
Autor:
Frank Bringezu, Phillip Bellion, Alexander Amberg, Jeffrey M. Birmingham, Alejandra Trejo-Martin, Glenn J. Myatt, Amy L. Mihalchik-Burhans, Amarjit Luniwal, Naomi L. Kruhlak, Rosalie K. Elespuru, Karen H. Watanabe-Sailor, Louise Neilson, Lidia Ceriani, Markus Frericks, Alessandro Brigo, John P. Rooney, Arun R. Pandiri, Helga Gerets, Alice Luu, Arianna Bassan, Angela White, Marc A. Beal, Federica Madia, Manuela Pavan, David Faulkner, Lennart T. Anger, Elena Lo Piparo, Marie C. Fortin, Jordi Mestres, Ian Crooks, David Woolley, Raymond R. Tice, Paul Fowler, Balasubramanian Manickam, David R. Jones, Cynthia V. Rider, Serena Manganelli, Juan Lopez-Belmonte, Gloria D. Jahnke, Kevin P. Cross, Romualdo Benigni
Publikováno v:
Comput Toxicol
Historically, identifying carcinogens has relied primarily on tumor studies in rodents, which require enormous resources in both money and time. In silico models have been developed for predicting rodent carcinogens but have not yet found general reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de085dd3094d276c69682e6dfe5bb402
https://europepmc.org/articles/PMC8967183/
https://europepmc.org/articles/PMC8967183/
