Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Balamurugan Packialakshmi"'
Autor:
Balamurugan Packialakshmi, Emily Limerick, Hans C. Ackerman, Xionghao Lin, Sergei Nekhai, James D. Oliver, Ian J. Stewart, Mark A. Knepper, Courtney Fitzhugh, Xiaoming Zhou
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Sickle cell nephropathy (SCN) is a leading cause of morbidity and mortality in sickle cell disease (SCD). Early intervention is crucial for mitigating its effects. However, current diagnostic methods rely on generic tests and may not detect SCN until
Externí odkaz:
https://doaj.org/article/7a05457372a249c682dc078f533230cd
Autor:
Balamurugan Packialakshmi, David M. Burmeister, Joseph A. Anderson, Judah Morgan, Georgetta Cannon, Juliann G. Kiang, Yuanyi Feng, Sang Lee, Ian J. Stewart, Xiaoming Zhou
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Hemorrhage is a leading cause of death in trauma. Tourniquets are effective at controlling extremity hemorrhage and have saved lives. However, tourniquets can cause ischemia reperfusion injury of limbs, leading to systemic inflammation and other adve
Externí odkaz:
https://doaj.org/article/e9e0b7b7723046dbbaebba84baa2068f
Autor:
Balamurugan Packialakshmi, Ian J. Stewart, David M. Burmeister, Kevin K. Chung, Xiaoming Zhou
Publikováno v:
Renal Failure, Vol 42, Iss 1, Pp 1042-1058 (2020)
While extensive research using animal models has improved the understanding of acute kidney injury (AKI), this knowledge has not been translated into effective treatments. Many promising interventions for AKI identified in mice and rats have not been
Externí odkaz:
https://doaj.org/article/3b2d8d79b33141c98bd5049a2d1dd589
Autor:
Balamurugan Packialakshmi, Ian J. Stewart, David M. Burmeister, Yuanyi Feng, Dennis P. McDaniel, Kevin K. Chung, Xiaoming Zhou
Publikováno v:
Physiological Reports, Vol 10, Iss 3, Pp n/a-n/a (2022)
Abstract The mechanisms by which lower limb ischemia/reperfusion induces acute kidney injury (AKI) remain largely uncharacterized. We hypothesized that tourniquet‐induced lower limb ischemia/reperfusion (TILLIR) would inhibit mitochondrial function
Externí odkaz:
https://doaj.org/article/192a49429952491da00fb1c138f3c772
Autor:
Balamurugan Packialakshmi, Rohana Liyanage, Jackson O. Lay, Jr., Ronald Okimoto, Narayan C. Rath
Publikováno v:
Biomarker Insights, Vol 2016, Iss 11, Pp 55-62 (2016)
Externí odkaz:
https://doaj.org/article/f21be3ee38e74930897bb9a37e20747d
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196277 (2018)
Increases of the activity of mitochondrial electron transport chain generally lead to increases of production of ATP and reactive oxygen species (ROS) as by-products. MnSOD is the first line of defense against the stress induced by mitochondrial ROS.
Externí odkaz:
https://doaj.org/article/5e920ab011f441a7968e3fbbd15feb6d
Autor:
Balamurugan, Packialakshmi, Sharanpreet, Hira, Yuanyi, Feng, David W, Scott, Jason R, Lees, Xiaoming, Zhou
Publikováno v:
Cellular immunology. 382
Multiple sclerosis is believed to be triggered by the interplay between the environmental and genetic factors. In contrast to the Paleolithic diet, the modern Western diet is high in Na
Autor:
Balamurugan Packialakshmi, Ian J. Stewart, David M. Burmeister, Xiaoming Zhou, Kevin K. Chung, Xiao C. Li, Manoocher Soleimani, Jia L. Zhuo, Lee Ann MacMillan‐Crow
Publikováno v:
The FASEB Journal. 36
Publikováno v:
Journal of Physiology and Biochemistry. 77:1-11
Dexamethasone augments mitochondrial protein abundance. The translocase of the outer membrane (Tom) of mitochondria plays a major role in importing largely cytosolically synthesized proteins into mitochondria. We hypothesize that dexamethasone upregu
Autor:
Ian J. Stewart, Balamurugan Packialakshmi, Xiaoming Zhou, David M. Burmeister, Kevin K. Chung
Publikováno v:
Renal Failure
article-version (VoR) Version of Record
Renal Failure, Vol 42, Iss 1, Pp 1042-1058 (2020)
article-version (VoR) Version of Record
Renal Failure, Vol 42, Iss 1, Pp 1042-1058 (2020)
While extensive research using animal models has improved the understanding of acute kidney injury (AKI), this knowledge has not been translated into effective treatments. Many promising interventions for AKI identified in mice and rats have not been