Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Balamurugan N. Appakalai"'
Autor:
Kyu Shik Mun, Kavisha Arora, Yunjie Huang, Fanmuyi Yang, Sunitha Yarlagadda, Yashaswini Ramananda, Maisam Abu-El-Haija, Joseph J. Palermo, Balamurugan N. Appakalai, Jaimie D. Nathan, Anjaparavanda P. Naren
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Defective CFTR protein, responsible for Cystic Fibrosis (CF), is highly expressed in pancreatic ductal epithelial cells (PDECs) but their impact on insulin secreting pancreatic islets is not fully understood. Here the authors develop a non-CF and CF
Externí odkaz:
https://doaj.org/article/fc92be52f03349bab8a0daee67da4a27
Autor:
Tijana Martinov, Kevin C. Osum, Adam L. Burrack, Balamurugan N. Appakalai, Nathanael L. Sahli, Jason S. Mitchell, Justin A. Spanier, Brian T. Fife, Christopher G. Tucker, Kristen E. Pauken, Klearchos K. Papas
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Type 1 diabetes is caused by autoreactive T cell-mediated β cell destruction. Even though co-inhibitory receptor programmed death-1 (PD-1) restrains autoimmunity, the expression and regulation of its cognate ligands on β cell remains unknown. Here,