TaqI and ApaI Variants of Vitamin D Receptor Gene Increase the Risk of Colorectal Cancer in a Saudi Population.

Autor: Al-Ghafari AB; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.; Cancer and Mutagenesis Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia., Balamash KS; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Al Doghaither HA; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.

Publikováno v: Saudi journal of medicine & medical sciences [Saudi J Med Med Sci] 2020 Sep-Dec; Vol. 8 (3), pp. 188-195. Date of Electronic Publication: 2020 Aug 20.

Serum vitamin D receptor (VDR) levels as a potential diagnostic marker for colorectal cancer.

Autor: Al-Ghafari AB; Department of Biochemistry, Faculty of Science, King Abdulaziz University, P.O.Box 80200, Jeddah 21589, Saudi Arabia.; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, P.O. Box 3270, Jeddah, 22252 Saudi Arabia.; Cancer and Mutagenesis Unit, King Fahd Medical Research Center, King Abdulaziz University, P.O. Box 3270, Jeddah, 22252 Saudi Arabia., Balamash KS; Department of Biochemistry, Faculty of Science, King Abdulaziz University, P.O.Box 80200, Jeddah 21589, Saudi Arabia., Al Doghaither HA; Department of Biochemistry, Faculty of Science, King Abdulaziz University, P.O.Box 80200, Jeddah 21589, Saudi Arabia.

Publikováno v: Saudi journal of biological sciences [Saudi J Biol Sci] 2020 Mar; Vol. 27 (3), pp. 827-832. Date of Electronic Publication: 2020 Jan 21.

Synthesis and in vitro antitumor activity of novel acylspermidine derivative N-(4-aminobutyl)-N-(3-aminopropyl)-8-hydroxy-dodecanamide (AAHD) against HepG2 cells.

Autor: Al-Malki AL; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia; Bioactive Natural Products Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Razvi SS; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Mohammed FA; Department of Biology, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Zamzami MA; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; Cancer Metabolism and Epigenetic Unit, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; Cancer and Mutagenesis Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia., Choudhry H; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia; Cancer Metabolism and Epigenetic Unit, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; Cancer and Mutagenesis Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia., Kumosani TA; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia; Production of Bioproducts for Industrial Applications Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Balamash KS; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Alshubaily FA; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., ALGhamdi SA; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Abualnaja KO; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia; Bioactive Natural Products Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Abdulaal WH; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia; Cancer Metabolism and Epigenetic Unit, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; Cancer and Mutagenesis Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia., Zeyadi MA; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Al-Zahrani MH; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Alhosin M; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; Cancer Metabolism and Epigenetic Unit, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; Cancer and Mutagenesis Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia., Asami T; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia; Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo, Tokyo 113-8657, Japan. Electronic address: asami@mail.ecc.u-tokyo.ac.jp., Moselhy SS; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia; Bioactive Natural Products Research Group, King Abdulaziz University, Jeddah, Saudi Arabia; Biochemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt. Electronic address: moselhy6@hotmail.com.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2019 Jul; Vol. 88, pp. 102937. Date of Electronic Publication: 2019 Apr 16.

Strigolactones-a novel class of phytohormones as anti-cancer agents.

Autor: Hasan MN; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Razvi SSI; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Kuerban A; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Balamash KS; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Al-Bishri WM; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Abulnaja KO; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Experimental Biochemistry Unit, King Fahd Medical Research Center, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Bioactive Natural Products Research Group, Jeddah, Saudi Arabia., Choudhry H; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Cancer Metabolism and Epigenetic Unit, Faculty of Science, Cancer and Mutagenesis Unit, King Fahd Medical Research Center, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Bioactive Natural Products Research Group, Jeddah, Saudi Arabia., Khan JA; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Biological Sciences Department (Genomic division), Faculty of Science, Jeddah, Saudi Arabia., Moselhy SS; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Experimental Biochemistry Unit, King Fahd Medical Research Center, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Bioactive Natural Products Research Group, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, Ain Shams University, Cairo, Egypt., M Z; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Cancer Metabolism and Epigenetic Unit, Faculty of Science, Cancer and Mutagenesis Unit, King Fahd Medical Research Center, Jeddah, Saudi Arabia., Kumosani TA; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Experimental Biochemistry Unit, King Fahd Medical Research Center, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Production of Bioproducts for Industrial Applications Research Group, Jeddah, Saudi Arabia., Al-Malki AL; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Experimental Biochemistry Unit, King Fahd Medical Research Center, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Bioactive Natural Products Research Group, Jeddah, Saudi Arabia., Alhosin M; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Cancer Metabolism and Epigenetic Unit, Faculty of Science, Cancer and Mutagenesis Unit, King Fahd Medical Research Center, Jeddah, Saudi Arabia., Asami T; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Cancer Metabolism and Epigenetic Unit, Faculty of Science, Cancer and Mutagenesis Unit, King Fahd Medical Research Center, Jeddah, Saudi Arabia.; Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan.

Publikováno v: Journal of pesticide science [J Pestic Sci] 2018 Aug 20; Vol. 43 (3), pp. 168-172.

Arginase overexpression and NADPH oxidase stimulation underlie impaired vasodilation induced by advanced glycation end products.

Autor: El-Bassossy HM; Department of Pharmacology & Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Pharmacology, Faculty of Pharmacy, Zagazig University, Egypt. Electronic address: helbassossy@kau.edu.sa., Neamatallah T; Department of Pharmacology & Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia., Balamash KS; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Saudi Arabia., Abushareb AT; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Saudi Arabia., Watson ML; Department of Pharmacy and Pharmacology, University of Bath, UK.

Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2018 May 23; Vol. 499 (4), pp. 992-997. Date of Electronic Publication: 2018 Apr 10.