Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Balaji M, Rao"'
Autor:
Ananya Mukherjee, Randhir Singh, Sreeram Udayan, Sayan Biswas, Pothula Purushotham Reddy, Saumya Manmadhan, Geen George, Shilpa Kumar, Ranabir Das, Balaji M Rao, Akash Gulyani
Publikováno v:
eLife, Vol 9 (2020)
Cell behavior is controlled through spatio-temporally localized protein activity. Despite unique and often contradictory roles played by Src-family-kinases (SFKs) in regulating cell physiology, activity patterns of individual SFKs have remained elusi
Externí odkaz:
https://doaj.org/article/82891c877b6a44bd978d8798b198d710
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1691 (2022)
Histone post-translational modifications are small chemical changes to the histone protein structure that have cascading effects on diverse cellular functions. Detecting histone modifications and characterizing their binding partners are critical ste
Externí odkaz:
https://doaj.org/article/b8553a527dda439b878359f82e65f0a1
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1634 (2021)
We present the construction and screening of yeast display libraries of post-translationally modified peptides wherein site-selective enzymatic treatment of linear peptides is achieved using bacterial transglutaminase. To this end, we developed two a
Externí odkaz:
https://doaj.org/article/1098d58f96d54d5fbfa814751bf06a6e
Autor:
Victoria Karakis, Mahe Jabeen, John W. Britt, Abigail Cordiner, Adam Mischler, Feng Li, Adriana San Miguel, Balaji M. Rao
Publikováno v:
Journal of Biological Chemistry. 299:104650
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2491
Cyclic peptides with engineered protein-binding activity have great potential as therapeutic and diagnostic reagents owing to their favorable properties, including high affinity and selectivity. Cyclic peptide binders have generally been isolated fro
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2491
pH-dependent antigen binding has proven useful in engineering next-generation therapeutics specifically via antibody recycling technology. This technology allows for half-life extension, thereby lowering the amount and frequency of dosing of therapeu
Publikováno v:
Acta Biomaterialia. 112:29-51
Progress in cell purification technology is critical to increase the availability of viable cells for therapeutic, diagnostic, and research applications. A variety of techniques are now available for cell separation, ranging from non-affinity methods
The use of immunodetection assays including the widely used enzyme-linked immunosorbent assay (ELISA) in applications such as point-of-care detection is often limited by the need for protein immobilization and multiple binding and washing steps. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebbea921e466154af58939241ce36436
https://doi.org/10.1101/2022.02.13.480265
https://doi.org/10.1101/2022.02.13.480265
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2446
The isolation of binding ligands from yeast-displayed combinatorial libraries has typically relied on the use of a soluble, recombinantly expressed form of the target protein when performing magnetic selections or fluorescence-activated cell sorting.