Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

Autor: Sieberts, Solveig K., Zhu, Fan, García-García, Javier, Stahl, Eli, Pratap, Abhishek, Pandey, Gaurav, Pappas, Dimitrios, Aguilar, Daniel, Anton, Bernat, Bonet, Jaume, Eksi, Ridvan, Fornés, Oriol, Guney, Emre, Li, Hongdong, Marín, Manuel Alejandro, Panwar, Bharat, Planas-Iglesias, Joan, Poglayen, Daniel, Cui, Jing, Falcao, Andre O., Suver, Christine, Hoff, Bruce, Balagurusamy, Venkat S. K., Dillenberger, Donna, Neto, Elias Chaibub, Norman, Thea, Aittokallio, Tero, Ammad-ud-din, Muhammad, Azencott, Chloe-Agathe, Bellón, Víctor, Boeva, Valentina, Bunte, Kerstin, Chheda, Himanshu, Cheng, Lu, Corander, Jukka, Dumontier, Michel, Goldenberg, Anna, Gopalacharyulu, Peddinti, Hajiloo, Mohsen, Hidru, Daniel, Jaiswal, Alok, Kaski, Samuel, Khalfaoui, Beyrem, Khan, Suleiman Ali, Kramer, Eric R., Marttinen, Pekka, Mezlini, Aziz M., Molparia, Bhuvan, Pirinen, Matti, Saarela, Janna, Samwald, Matthias, Stoven, Véronique, Tang, Hao, Tang, Jing, Torkamani, Ali, Vert, Jean-Phillipe, Wang, Bo, Wang, Tao, Wennerberg, Krister, Wineinger, Nathan E., Xiao, Guanghua, Xie, Yang, Yeung, Rae, Zhan, Xiaowei, Zhao, Cheng, Calaza, Manuel, Elmarakeby, Haitham, Heath, Lenwood S., Long, Quan, Moore, Jonathan D., Opiyo, Stephen Obol, Savage, Richard S., Zhu, Jun, Greenberg, Jeff, Kremer, Joel, Michaud, Kaleb, Barton, Anne, Coenen, Marieke, Mariette, Xavier, Miceli, Corinne, Shadick, Nancy, Weinblatt, Michael, de Vries, Niek, Tak, Paul P., Gerlag, Danielle, Huizinga, Tom W. J., Kurreeman, Fina, Allaart, Cornelia F., Louis Bridges Jr., S., Criswell, Lindsey, Moreland, Larry, Klareskog, Lars, Saevarsdottir, Saedis, Padyukov, Leonid, Gregersen, Peter K., Friend, Stephen, Plenge, Robert, Stolovitzky, Gustavo, Oliva, Baldo, Guan, Yuanfang, Mangravite, Lara M., Bridges, S. Louis

Publikováno v: Nature Communications, 7:12460 (2016). Nature Publishing Group
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature communications, 7. Nature Publishing Group
Nature Communications
Nature Communications, 2016, 7, pp.12460. ⟨10.1038/ncomms12460⟩
Nature Communications, 7:12460. Nature Publishing Group
Nature Communications, Nature Publishing Group, 2016, 7, pp.12460. ⟨10.1038/ncomms12460⟩
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications, 7
Sieberts, S K, Zhu, F, García-García, J, Stahl, E, Pratap, A, Pandey, G, Pappas, D, Aguilar, D, Anton, B, Bonet, J, Eksi, R, Fornés, O, Guney, E, Li, H, Marín, M A, Panwar, B, Planas-Iglesias, J, Poglayen, D, Cui, J, Falcao, A O, Suver, C, Hoff, B, Balagurusamy, V S K, Dillenberger, D, Neto, E C, Norman, T, Aittokallio, T, Ammad-Ud-Din, M, Azencott, C A, Bellón, V, Boeva, V, Bunte, K, Chheda, H, Cheng, L, Corander, J, Dumontier, M, Goldenberg, A, Gopalacharyulu, P, Hajiloo, M, Hidru, D, Jaiswal, A, Kaski, S, Khalfaoui, B, Khan, S A, Kramer, E R, Marttinen, P, Mezlini, A M, Molparia, B, Pirinen, M, Saarela, J, Samwald, M, Stoven, V, Tang, H, Tang, J, Torkamani, A, Vert, J P, Wang, B, Wang, T, Wennerberg, K, Wineinger, N E, Xiao, G, Xie, Y, Yeung, R, Zhan, X, Zhao, C, Greenberg, J, Kremer, J, Michaud, K, Barton, A, Coenen, M, Mariette, X, Miceli, C, Shadick, N, Weinblatt, M, De Vries, N, Tak, P P, Gerlag, D, Huizinga, T W J, Kurreeman, F, Allaart, C F, Louis Bridges, S, Criswell, L, Moreland, L, Klareskog, L, Saevarsdottir, S, Padyukov, L, Gregersen, P K, Friend, S, Plenge, R, Stolovitzky, G, Oliva, B, Guan, Y & Mangravite, L M 2016, ' Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis ', Nature Communications, vol. 7, 12460 . https://doi.org/10.1038/ncomms12460

Rheumatoid arthritis (RA) affects millions world-wide. While anti-TNF treatment is widely used to reduce disease progression, treatment fails in ∼one-third of patients. No biomarker currently exists that identifies non-responders before treatment.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe800839878ab5e485119caf3f56464
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