Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Balachandar Venkatesan"'
Autor:
R M Anjana, Nagaraj Manickam, Viswanathan Mohan, Isaivani Jayachandran, Balachandar Venkatesan, Muthuswamy Balasubramanyam, Saravanakumar Sundararajan, S C Subramanian
Publikováno v:
Journal of Endocrinological Investigation. 44:1395-1405
We earlier reported that Sestrin2 regulates monocyte activation and atherogenic events through AMPK-mTOR nexus under high-glucose and dyslipidemic conditions. However, the statuses of Sestrins in diabetes and dyslipidemia are not known. We report her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df120c4e7ef24afc39d2049bf14ffb71
https://doi.org/10.1007/s40618-020-01429-9
https://doi.org/10.1007/s40618-020-01429-9
Autor:
Viswanathan Mohan, Balachandar Venkatesan, Saravanakumar Venkatesan, Isaivani Jayachandran, Saravanakumar Sundararajan, Muthuswamy Balasubramanyam, Nagaraj Manickam
Publikováno v:
Indian Journal of Inflammation Research. 4
Diabetes is a group of metabolic disorders characterized by hyperglycemia and associated chronic complications including cardiovascular diseases. Hyperglycemia induces various stress conditions including oxidative /endoplasmic reticulum (ER) stress,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28f52d48b63b522cdd22ad6df3ade5fb
https://doi.org/10.15305/ijir/v4i1/331
https://doi.org/10.15305/ijir/v4i1/331
Autor:
Nandini Ghosh-Choudhury, Falguni Das, Goutam Ghosh Choudhury, Balakuntalam S. Kasinath, Balachandar Venkatesan
Publikováno v:
American Journal of Physiology-Renal Physiology. 313:F291-F307
Increased expression of PDGF receptor-β (PDGFRβ) has been shown in renal proximal tubules in mice with diabetes. The core molecular network used by high glucose to induce proximal tubular epithelial cell collagen I (α2) expression is poorly unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ad6dd8d6613d13fc2e637383215c8b
https://doi.org/10.1152/ajprenal.00666.2016
https://doi.org/10.1152/ajprenal.00666.2016
Autor:
Saravanakumar Sundararajan, Isaivani Jayachandran, Balachandar Venkatesan, Viswanathan Mohan, Muthuswamy Balasubramanyam, Nagaraj Manickam
Publikováno v:
Journal of cellular biochemistry.
The vicious cycle between hyperinsulinemia and insulin resistance results in the progression of atherosclerosis in the vessel wall. The complex interaction between hyperglycemia and lipoprotein abnormalities promotes the development of atherogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19178a6918152c82c503317b8bf86a61
https://pubmed.ncbi.nlm.nih.gov/30450765
https://pubmed.ncbi.nlm.nih.gov/30450765
Autor:
Prabu Paramasivam, Saravanakumar Sundararajan, Nagaraj Manickam, Muthuswamy Balasubramanyam, Shanthirani C. Subramanian, Balachandar Venkatesan, Isaivani Jayachandran, Viswanathan Mohan
Publikováno v:
Clinical biochemistry. 50(15)
Aim Asymmetric dimethylarginine (ADMA) is involved in the regulation of nitric oxide synthesis and in the maintenance of vascular tone and structure. But the role and status of ADMA in diabetes induced kidney injury is not clear. Hence this study is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dccc180d24966dd2ccf51902b8ab571
https://pubmed.ncbi.nlm.nih.gov/28495185
https://pubmed.ncbi.nlm.nih.gov/28495185
Autor:
Nandini Ghosh-Choudhury, Nirmalya Dey, Falguni Das, Goutam Ghosh Choudhury, Balachandar Venkatesan, Balakuntalam S. Kasinath
Publikováno v:
Cellular Signalling. 23:1311-1319
The Akt kinase signaling pathway is frequently deregulated in many human diseases including cancer, autoimmune disease and diabetes. In nephropathy, associated with diabetes, increased Akt signal transduction results in glomerular especially mesangia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5e097cf3d8182a01fddcc9ffb41633
https://doi.org/10.1016/j.cellsig.2011.03.012
https://doi.org/10.1016/j.cellsig.2011.03.012
Autor:
Balachandar Venkatesan, Anthony J. Valente, Patrice Delafontaine, Prakash Srinivasan Timiri Shanmugam, Sumanth D. Prabhu, Bysani Chandrasekar
Publikováno v:
Journal of Molecular and Cellular Cardiology. 49:655-663
The transmembrane glycoprotein extracellular matrix metalloproteinase inducer (EMMPRIN), and the pleiotropic proinflammatory cytokine interleukin (IL)-18, play critical roles in myocardial remodeling, by inducing matrix degrading metalloproteinases (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6452fa0f24bf2a20567a6cc338e7d3a0
https://doi.org/10.1016/j.yjmcc.2010.05.007
https://doi.org/10.1016/j.yjmcc.2010.05.007
Autor:
Xiaonan Li, Goutam Ghosh Choudhury, Falguni Das, Balakuntalam S. Kasinath, Nandini Ghosh-Choudhury, Nirmalya Dey, Balachandar Venkatesan, Jeffrey L. Barnes
Publikováno v:
Journal of Cellular Physiology. 225:27-41
Diabetic nephropathy manifests aberrant activation of TORC1, which senses key signals to modulate protein synthesis and renal hypertrophy. PRAS40 has recently been identified as a raptor-interacting protein and is a component and a constitutive inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7f739ad7a8f1f42f494bf23db9e08b9
https://doi.org/10.1002/jcp.22186
https://doi.org/10.1002/jcp.22186
Autor:
Bysani Chandrasekar, Anthony J. Valente, Balachandar Venkatesan, Srinivas Mummidi, Patrice Delafontaine, Robert A. Clark, Kaliyamurthi Venkatachalam, Sumanth D. Prabhu
Publikováno v:
Cellular Signalling. 22:809-820
The anthracycline antibiotic doxorubicin (DOX) is a potent cancer chemotherapeutic agent that exerts both acute and chronic cardiotoxicity. Here we show that in adult mouse cardiomyocytes, DOX activates (i) the pro-apoptotic p53, (ii) p38MAPK and JNK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1e352eeb9cf292e6b4a9ae1ca1a7ee
https://doi.org/10.1016/j.cellsig.2010.01.005
https://doi.org/10.1016/j.cellsig.2010.01.005
Autor:
Anthony J. Valente, Bysani Chandrasekar, Balachandar Venkatesan, Sailesh Nandish, Jane E.B. Reusch, Robert A. Clark, Peter C. Melby, Kaliyamurthi Venkatachalam
Publikováno v:
Journal of Biological Chemistry. 284:14414-14427
WNT1-inducible signaling pathway protein-1 (WISP1), a member of the CYR61/CTGF/Nov family of growth factors, can mediate cell growth, transformation, and survival. Previously we demonstrated that WISP1 is up-regulated in post-infarct heart, stimulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20acc7fe6db26732cfa5ed9eafc401da
https://doi.org/10.1074/jbc.m809757200
https://doi.org/10.1074/jbc.m809757200