Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Balachandar Selvakumar"'
Autor:
Learta Pervizaj-Oruqaj, Balachandar Selvakumar, Maximiliano Ruben Ferrero, Monika Heiner, Christina Malainou, Rolf David Glaser, Jochen Wilhelm, Marek Bartkuhn, Astrid Weiss, Ioannis Alexopoulos, Biruta Witte, Stefan Gattenlöhner, István Vadász, Rory Edward Morty, Werner Seeger, Ralph Theo Schermuly, Ana Ivonne Vazquez-Armendariz, Susanne Herold
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Influenza A virus (IAV) infection mobilizes bone marrow-derived macrophages (BMDM) that gradually undergo transition to tissue-resident alveolar macrophages (TR-AM) in the inflamed lung. Combining high-dimensional single-cell transcriptomics
Externí odkaz:
https://doaj.org/article/78b9668d870244cca6b2f62d7f2fe96b
Increased blood immune regulatory cells in severe COVID-19 with autoantibodies to type I interferons
Autor:
Fatemeh Saheb Sharif-Askari, Narjes Saheb Sharif-Askari, Shirin Hafezi, Hawra Ali Hussain Alsayed, Balachandar Selvakumar, Mariam Wed Abdelaziz Eladham, Bushra Mdkhana, Ola Salam Bayram, Mohamad-Hani Temsah, Rabih Halwani
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The hallmark of severe COVID-19 is an uncontrolled inflammatory response, resulting from poorly understood immunological dysfunction. While regulatory T (Treg) and B (Breg) cells, as the main elements of immune homeostasis, contribute to the
Externí odkaz:
https://doaj.org/article/85279681838e4adcb0032b232cf22eeb
Autor:
Mariam Wed Eladham, Balachandar Selvakumar, Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Saleh Mohamed Ibrahim, Rabih Halwani
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e24032- (2024)
The link between gut and lung starts as early as during organogenesis. Even though they are anatomically distinct, essential bidirectional crosstalk via complex mechanisms supports GLA. Emerging studies have demonstrated the association of gut and lu
Externí odkaz:
https://doaj.org/article/ac763e0834d9490da15ff32057c84d9c
Autor:
Djuro Kosanovic, Ujjwal Deo, Henning Gall, Balachandar Selvakumar, Susanne Herold, Astrid Weiss, Aleksandar Petrovic, Akylbek Sydykov, Hossein Ardeschir Ghofrani, Ralph Theo Schermuly
Publikováno v:
Pulmonary Circulation, Vol 9 (2019)
It has been shown previously that increased circulating endothelial cells-derived extracellular vesicles represent an important pathological attribute of pulmonary hypertension. Although it is a well-known fact that inflammatory cells may also releas
Externí odkaz:
https://doaj.org/article/877b02aebd514c459b58e6c8cbb0cbfc
Autor:
Henning Petersen, Ahmed Mostafa, Mohamed A. Tantawy, Azeem A. Iqbal, Donata Hoffmann, Aravind Tallam, Balachandar Selvakumar, Frank Pessler, Martin Beer, Silke Rautenschlein, Stephan Pleschka
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The 2009 pandemic influenza A virus (IAV) H1N1 strain (H1N1pdm09) has widely spread and is circulating in humans and swine together with other human and avian IAVs. This fact raises the concern that reassortment between H1N1pdm09 and co-circulating v
Externí odkaz:
https://doaj.org/article/557a20acc5db4afd9f84ed8e065eb8c4
Autor:
Fatemeh Saheb Sharif-Askari, Shirin Hafezi, Narjes Saheb Sharif-Askari, Hawra Ali Hussain Alsayed, Bushra Mdkhana, Balachandar Selvakumar, Mohamad-Hani Temsah, Basema Saddik, Fatme Al Anouti, Rabih Halwani
Publikováno v:
Life sciences. 307
The ability of vitamin D (VitD) to modulate immune responses in the clinical setting of COVID-19 infection is not well investigated. This study aimed to evaluate the ability of VitD to attenuate inflammatory responses in patients with severe COVID-19
Autor:
Elsa T. Roxlau, Oleg Pak, Stefan Hadzic, Claudia F. Garcia-Castro, Marija Gredic, Cheng-Yu Wu, Julia Schäffer, Balachandar Selvakumar, Alexandra Pichl, David Spiegelberg, Janik Deutscher, Mariola Bednorz, Katharina Schäfer, Simone Kraut, Djuro Kosanovic, Esraa M Zeidan, Baktybek Kojonazarov, Susanne Herold, Ievgen Strielkov, Andreas Guenther, Jochen Wilhelm, Mohamed M. A. Khalifa, Ashraf Taye, Ralf P. Brandes, Matthias Hecker, Friedrich Grimminger, Hossein A. Ghofrani, Ralph T. Schermuly, Werner Seeger, Natascha Sommer, Norbert Weissmann
Publikováno v:
European Respiratory Journal. :2200951
Electronic cigarette (e-cigarette) vapour is gaining popularity as an alternative to tobacco smoking and can induce acute lung injury. However, the specific role of nicotine in e-cigarette vapour and its long-term effects on the airways, lung parench
Autor:
Susanne Herold, Lucas Kimmig, Michael Wetstein, Martin Langelage, Christiane Herden, Balachandar Selvakumar, Julian Better, Kernt Köhler, Borros Arneth, Ulrich Matt, C. Malainou
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 64:641-643
Autor:
Sophia Kirschke, Ireti Ogunsulire, Balachandar Selvakumar, Neele Schumacher, Tanya Sezin, Stefan Rose-John, Alexander Scheffold, Christoph Garbers, Juliane Lokau
Publikováno v:
The Journal of biological chemistry. 298(6)
The cytokine interleukin-2 (IL-2) plays a critical role in controlling the immune homeostasis by regulating the proliferation and differentiation of immune cells, especially T cells. IL-2 signaling is mediated via the IL-2 receptor (IL-2R) complex, w
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1869:119192
A Disintegrin and Metalloproteinases (ADAM)-10 is a member of a family of membrane-anchored proteinases that regulate a broad range of cellular functions with central roles within the immune system. This has spurred the interest to modulate ADAM acti