Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Bala K. Prabhala"'
Autor:
Hani Gharabli, Maria Rafiq, Anna Iqbal, Ruyu Yan, Nanda G. Aduri, Neha Sharma, Bala K. Prabhala, Osman Mirza
Publikováno v:
Biology, Vol 12, Iss 5, p 651 (2023)
Proton-coupled oligopeptide transporters (POTs) are a fundamental part of the cellular transport machinery that provides plants, bacteria, and mammals with nutrition in the form of short peptides. However, POTs are not restricted to peptide transport
Externí odkaz:
https://doaj.org/article/5a55a27543af4116b6bd3f7f16ba4799
Autor:
Moazur Rahman, Osman Mirza, Bala K. Prabhala, Magnus Borup Bloch, Thomas Boesen, Heidi A. Ernst, Maria Rafiq, Nadia Mirza, Michael Gajhede, Nanda G. Aduri, Soban Tufail, Nicholas M.I. Taylor
Publikováno v:
Rafiq, M, Ernst, H A, Aduri, N G, Prabhala, B K, Tufail, S, Rahman, M, Bloch, M B, Mirza, N, Taylor, N M I, Boesen, T, Gajhede, M & Mirza, O 2022, ' Expression, purification and characterization of human proton-coupled oligopeptide transporter 1 hPEPT1 ', Protein Expression and Purification, vol. 190, 105990 . https://doi.org/10.1016/j.pep.2021.105990
Rafiq, M, Ernst, H A, Aduri, N G, Prabhala, B K, Tufail, S, Rahman, M, Bloch, M B, Mirza, N, Taylor, N M, Boesen, T, Gajhede, M & Mirza, O 2022, ' Expression, purification and characterization of human proton-coupled oligopeptide transporter 1 hPEPT1 ', Protein Expression and Purification, vol. 190, 105990 . https://doi.org/10.1016/j.pep.2021.105990
Rafiq, M, Ernst, H A, Aduri, N G, Prabhala, B K, Tufail, S, Rahman, M, Bloch, M B, Mirza, N, Taylor, N M, Boesen, T, Gajhede, M & Mirza, O 2022, ' Expression, purification and characterization of human proton-coupled oligopeptide transporter 1 hPEPT1 ', Protein Expression and Purification, vol. 190, 105990 . https://doi.org/10.1016/j.pep.2021.105990
The human peptide transporter hPEPT1 (SLC15A1) is responsible for uptake of dietary di- and tripeptides and a number of drugs from the small intestine by utilizing the proton electrochemical gradient, and hence an important target for peptide-like dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769cbac63b46511a7065e6627c197f41
https://pubmed.ncbi.nlm.nih.gov/34637915
https://pubmed.ncbi.nlm.nih.gov/34637915
Autor:
Biljana Mojsoska, Håvard Jenssen, Eva Aryal, Marcus M K Hughes, Bala K. Prabhala, Elnaz Safari
Publikováno v:
Hughes, M M K, Aryal, E, Safari, E, Mojsoska, B, Jenssen, H & Prabhala, B K 2021, ' Current state of slc and abc transporters in the skin and their relation to sweat metabolites and skin diseases ', Proteomes, vol. 9, no. 2, 23 . https://doi.org/10.3390/proteomes9020023
Proteomes, Vol 9, Iss 23, p 23 (2021)
Proteomes
Proteomes, Vol 9, Iss 23, p 23 (2021)
Proteomes
With a relatively large surface area (2 m2) and 15% of total body mass, the skin forms the largest organ of the human body. The main functions of the skin include regulation of body temperature by insulation or sweating, regulation of the nervous sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d35a378211b95c551838820e05ce0a0
https://findresearcher.sdu.dk:8443/ws/files/183585307/proteomes_09_00023_v2.pdf
https://findresearcher.sdu.dk:8443/ws/files/183585307/proteomes_09_00023_v2.pdf
Autor:
Bala K, Prabhala, Moazur, Rahman, Hussam H, Nour-Eldin, Flemming Steen, Jørgensen, Osman, Mirza
Publikováno v:
Advances in protein chemistry and structural biology. 123
PTR2/POT/NPF are a family of primarily proton coupled transporters that belong to the major facilitator super family and are found across most kingdoms of life. They are involved in uptake of nutrients, hormones, ions and several orally administered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::529b2ddee2b983d18b8973c9ca439143
https://pubmed.ncbi.nlm.nih.gov/33485485
https://pubmed.ncbi.nlm.nih.gov/33485485
Publikováno v:
Advances in Protein Chemistry and Structural Biology ISBN: 9780128220870
Prabhala, B K, Rahman, M, Nour-eldin, H H, Jørgensen, F S & Mirza, O 2021, PTR2/POT/NPF transporters : what makes them tick? in R Donev (ed.), Advances in Protein Chemistry and Structural Biology : Transport Proteins . 1. edn, vol. 123, Academic Press, Advances in Protein Chemistry and Structural Biology, vol. 123, pp. 219-240 . https://doi.org/10.1016/bs.apcsb.2020.10.002
Prabhala, B K, Rahman, M, Nour-eldin, H H, Jørgensen, F S & Mirza, O 2021, PTR2/POT/NPF transporters : what makes them tick? in R Donev (ed.), Advances in Protein Chemistry and Structural Biology : Transport Proteins . 1. edn, vol. 123, Academic Press, Advances in Protein Chemistry and Structural Biology, vol. 123, pp. 219-240 . https://doi.org/10.1016/bs.apcsb.2020.10.002
PTR2/POT/NPF are a family of primarily proton coupled transporters that belong to the major facilitator super family and are found across most kingdoms of life. They are involved in uptake of nutrients, hormones, ions and several orally administered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2b89e861654bc4f8374bbe039fb81f
https://doi.org/10.1016/bs.apcsb.2020.10.002
https://doi.org/10.1016/bs.apcsb.2020.10.002
Autor:
Paul R. Hansen, Natalia Molchanova, Annelise E. Barron, Bala K. Prabhala, Håvard Jenssen, Reidar Lund, Kristian Birk Sørensen, Josefine Eilsø Nielsen
Publikováno v:
Scientific Reports
Molchanova, N, Nielsen, J E, Sørensen, K B, Prabhala, B K, Hansen, P R, Lund, R, Barron, A E & Jenssen, H 2020, ' Halogenation as a tool to tune antimicrobial activity of peptoids ', Scientific Reports, vol. 10, no. 1, 14805 . https://doi.org/10.1038/s41598-020-71771-8
Molchanova, N, Nielsen, J E, Sørensen, K B, Prabhala, B K, Hansen, P R, Lund, R, Barron, A E & Jenssen, H 2020, ' Halogenation as a tool to tune antimicrobial activity of peptoids ', Scientific Reports, vol. 10, 14805 . https://doi.org/10.1038/s41598-020-71771-8
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
'Scientific Reports ', vol: 10, pages: 14805-1-14805-10 (2020)
Molchanova, N, Nielsen, J E, Sørensen, K B, Prabhala, B K, Hansen, P R, Lund, R, Barron, A E & Jenssen, H 2020, ' Halogenation as a tool to tune antimicrobial activity of peptoids ', Scientific Reports, vol. 10, no. 1, 14805 . https://doi.org/10.1038/s41598-020-71771-8
Molchanova, N, Nielsen, J E, Sørensen, K B, Prabhala, B K, Hansen, P R, Lund, R, Barron, A E & Jenssen, H 2020, ' Halogenation as a tool to tune antimicrobial activity of peptoids ', Scientific Reports, vol. 10, 14805 . https://doi.org/10.1038/s41598-020-71771-8
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
'Scientific Reports ', vol: 10, pages: 14805-1-14805-10 (2020)
Antimicrobial peptides have attracted considerable interest as potential new class of antibiotics against multi-drug resistant bacteria. However, their therapeutic potential is limited, in part due to susceptibility towards enzymatic degradation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c85d7d68a4d5ba116ca095bc721607f
https://pubmed.ncbi.nlm.nih.gov/32908179
https://pubmed.ncbi.nlm.nih.gov/32908179
Autor:
Christoffer Brasen, Arpan Sharma, Moazur Rahman, Mazhar Iqbal, Aqsa Shaheen, Nanda G. Aduri, Osman Mirza, Paul R. Hansen, Bala K. Prabhala, Michael Gajhede, Neha Sharma
Publikováno v:
Journal of Biological Chemistry. 293:1007-1017
Chloramphenicol (Cam) is a broad-spectrum antibiotic used to combat bacterial infections in humans and animals. Cam export from bacterial cells is one of the mechanisms by which pathogens resist Cam's antibacterial effects, and several different prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b1b160119b00281329e2ce441a56b9
https://doi.org/10.1074/jbc.m117.805960
https://doi.org/10.1074/jbc.m117.805960
Publikováno v:
Brain Research. 1665:74-79
Previously, we presented electrophysiological evidence for presence in mice brain slices of functional cannabinoid type I receptors (CB1Rs) within the laterodorsal tegmentum (LDT), a brain stem nucleus critical in control of arousal and rapid eye mov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0206938e52ffe62cec6c44bf58c266ec
https://doi.org/10.1016/j.brainres.2017.04.003
https://doi.org/10.1016/j.brainres.2017.04.003
Autor:
Bala K. Prabhala, Douglas B. Kell, Behrooz Darbani, Steven Axel van der Hoek, Jacqueline B. Medina, Irina Borodina, Mathias Bernfried Biron, Karolina E. Zugaj, Milica Randelovic
Publikováno v:
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
van der Hoek, S A, Darbani, B, Zugaj, K E, Prabhala, B K, Biron, M B, Randelovic, M, Medina, J B, Kell, D B & Borodina, I 2019, ' Engineering the Yeast Saccharomyces cerevisiae for the Production of L-(+)-Ergothioneine ', Frontiers in Bioengineering and Biotechnology, vol. 7, 262 . https://doi.org/10.3389/fbioe.2019.00262
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
van der Hoek, S A, Darbani, B, Zugaj, K E, Prabhala, B K, Biron, M B, Randelovic, M, Medina, J B, Kell, D B & Borodina, I 2019, ' Engineering the Yeast Saccharomyces cerevisiae for the Production of L-(+)-Ergothioneine ', Frontiers in Bioengineering and Biotechnology, vol. 7, 262 . https://doi.org/10.3389/fbioe.2019.00262
L-(+)-Ergothioneine is an unusual, naturally occurring antioxidant nutraceutical that has been shown to help reduce cellular oxidative damage. Humans do not biosynthesise it, so can acquire it only from their diet; it exploits a specific transporter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323ceeb7f8d9222ca59bcc5883e53a0a
https://doi.org/10.3389/fbioe.2019.00262
https://doi.org/10.3389/fbioe.2019.00262
Autor:
Swati Irani, Shadrack M. Mutuku, Paul J. Trim, Margaret M. Centenera, Lisa M. Butler, Douglas A. Brooks, Bala K. Prabhala, Jurgen Stahl, Kayla L. Bremert, Marten F. Snel, Jessica M. Logan
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Mutuku, S M, Trim, P J, Prabhala, B K, Irani, S, Bremert, K L, Logan, J M, Brooks, D A, Stahl, J, Centenera, M M, Snel, M F & Butler, L M 2019, ' Evaluation of Small Molecule Drug Uptake in Patient-Derived Prostate Cancer Explants by Mass Spectrometry ', Scientific Reports, vol. 9, no. 1, 15008 . https://doi.org/10.1038/s41598-019-51549-3
Scientific Reports
Mutuku, S M, Trim, P J, Prabhala, B K, Irani, S, Bremert, K L, Logan, J M, Brooks, D A, Stahl, J, Centenera, M M, Snel, M F & Butler, L M 2019, ' Evaluation of Small Molecule Drug Uptake in Patient-Derived Prostate Cancer Explants by Mass Spectrometry ', Scientific Reports, vol. 9, no. 1, 15008 . https://doi.org/10.1038/s41598-019-51549-3
Scientific Reports
Patient-derived explant (PDE) culture of solid tumors is increasingly being applied to preclinical evaluation of novel therapeutics and for biomarker discovery. In this technique, treatments are added to culture medium and penetrate the tissue via a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5cc3e7aa307d58acdfb0941d30eae46
https://hdl.handle.net/11541.2/139813
https://hdl.handle.net/11541.2/139813