Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Balázs Pósfai"'
Autor:
Péter Berki, Csaba Cserép, Zsuzsanna Környei, Balázs Pósfai, Eszter Szabadits, Andor Domonkos, Anna Kellermayer, Miklós Nyerges, Xiaofei Wei, Istvan Mody, Araki Kunihiko, Heinz Beck, He Kaikai, Wang Ya, Nikolett Lénárt, Zhaofa Wu, Miao Jing, Yulong Li, Attila I. Gulyás, Ádám Dénes
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Acute brain slices represent a workhorse model for studying the central nervous system (CNS) from nanoscale events to complex circuits. While slice preparation inherently involves tissue damage, it is unclear how microglia, the main immune c
Externí odkaz:
https://doaj.org/article/23b86858b05540109a8a453d5e619efd
Autor:
Krisztina Tóth, Nikolett Lénárt, Péter Berki, Rebeka Fekete, Eszter Szabadits, Balázs Pósfai, Csaba Cserép, Ahmad Alatshan, Szilvia Benkő, Dániel Kiss, Christian A Hübner, Attila Gulyás, Kai Kaila, Zsuzsanna Környei, Ádám Dénes
Publikováno v:
PLoS Biology, Vol 20, Iss 1, p e3001526 (2022)
The NKCC1 ion transporter contributes to the pathophysiology of common neurological disorders, but its function in microglia, the main inflammatory cells of the brain, has remained unclear to date. Therefore, we generated a novel transgenic mouse lin
Externí odkaz:
https://doaj.org/article/d912baf97e3f406590c12031ce06e71c
Autor:
Virág T. Takács, Csaba Cserép, Dániel Schlingloff, Balázs Pósfai, András Szőnyi, Katalin E. Sos, Zsuzsanna Környei, Ádám Dénes, Attila I. Gulyás, Tamás F. Freund, Gábor Nyiri
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Acetylcholine (ACh) release in the central nervous system is thought to be unitary and mediated non-synaptically in volume transmission. Here, Takács and colleagues show cholinergic terminals juxtapose GABAergic synapses anatomically and functionall
Externí odkaz:
https://doaj.org/article/9152c00a8484415dbce6f767cb36a338
Autor:
Péter Berki, Csaba Cserép, Balázs Pósfai, Eszter Szabadits, Zsuzsanna Környei, Anna Kellermayer, Miklós Nyerges, Attila I. Gulyás, Ádám Dénes
Microglia, the main immune cells of the central nervous system (CNS) have long been known for their remarkable sensitivity to tissue disturbance or injury, but its implications to the interpretation of results fromex vivomodels of the CNS have remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a329f077f84d49c2049aae6b60670151
https://doi.org/10.1101/2022.04.12.487998
https://doi.org/10.1101/2022.04.12.487998
Autor:
Eszter Császár, Nikolett Lénárt, Csaba Cserép, Zsuzsanna Környei, Rebeka Fekete, Balázs Pósfai, Diána Balázsfi, Balázs Hangya, Anett D. Schwarcz, Eszter Szabadits, Dávid Szöllősi, Krisztián Szigeti, Domokos Máthé, Brian L. West, Katalin Sviatkó, Ana Rita Brás, Jean-Charles Mariani, Andrea Kliewer, Zsolt Lenkei, László Hricisák, Zoltán Benyó, Mária Baranyi, Beáta Sperlágh, Ákos Menyhárt, Eszter Farkas, Ádám Dénes
Publikováno v:
Journal of experimental medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2022, 219 (3), pp.e20211071. ⟨10.1084/jem.20211071⟩
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2022, 219 (3), pp.e20211071. ⟨10.1084/jem.20211071⟩
International audience; Microglia, the main immunocompetent cells of the brain, regulate neuronal function, but their contribution to cerebral blood flow (CBF) regulation has remained elusive. Here, we identify microglia as important modulators of CB
Autor:
László Hricisák, Rebeka Fekete, Ákos Menyhárt, Balázs Pósfai, Diána Balázsfi, Domokos Máthé, A. R. Bras, Eszter Császár, Zsuzsanna Környei, D. Szollosi, Eszter Farkas, Katalin Sviatkó, Jean Mariani, Anett D. Schwarcz, Balázs Hangya, Zoltán Benyó, Krisztián Szigeti, Adam Denes, Brian L. West, Nikolett Lénárt, Zsolt Lenkei, C. Cserep, Beáta Sperlágh, A. Kliewer, Mária Baranyi
Publikováno v:
bioRxiv.org-the preprint server for Biology
bioRxiv
bioRxiv
Microglia, the main immunocompetent cells of the brain regulate neuronal function in health and disease, but their contribution to cerebral blood flow (CBF) remained elusive. Here we identify microglia as important modulators of CBF both under physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93dae79a8cf80ad6fadd2a1b783f9761
https://doi.org/10.1101/2021.02.04.429741
https://doi.org/10.1101/2021.02.04.429741
Autor:
Kai Kaila, Christian A. Hübner, Csaba Cserép, Zsuzsanna Környei, Ahmad Alatshan, Balázs Pósfai, Dániel Kiss, Szilvia Benkő, Rebeka Fekete, Krisztina Tóth, Péter Berki, Eszter Szabadits, Adam Denes, Nikolett Lénárt, Attila I. Gulyás
The NKCC1 ion transporter contributes to the pathophysiology of common neurological disorders, but its function in microglia, the main inflammatory cells of the brain, has remained unclear to date. Therefore, we generated a novel transgenic mouse lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bb9b2794b8eb074d24708aea4e8ad5a
https://doi.org/10.1101/2021.01.21.427597
https://doi.org/10.1101/2021.01.21.427597
Publikováno v:
Neuron
The functional contribution of microglia to normal brain development, healthy brain function, and neurological disorders is increasingly recognized. However, until recently, the nature of intercellular interactions mediating these effects remained la
Autor:
Gábor Tamás, István Katona, Katinka Ujvári, Gábor Molnár, Balázs Pósfai, Bernadett Martinecz, Tibor Hortobágyi, Zsuzsanna Környei, Róbert Szipőcs, Barbara Orsolits, Marco Duering, Mária Baranyi, Zsófia Maglóczky, Zsolt Lele, Anett D. Schwarcz, Nikolett Lénárt, Arthur Liesz, Rebeka Fekete, Ferenc Erdélyi, Krisztina Tóth, Adam Denes, Michael M. Tamkun, Eszter Szabadits, Steffanie Heindl, Csaba Cserép, Gábor Szabó, Zsófia I. László, Beáta Sperlágh, László Csiba, Benno Gesierich
Publikováno v:
Science
Microglia take control Changes in the activity of microglia, the primary immune cells of the central nervous system, are linked with major human diseases, including stroke, epilepsy, psychiatric disorders, and neurodegeneration. Cserép et al. identi
Autor:
Eszter Császár, Barbara Orsolits, Tamás Szlepák, Eszter Farkas, Csaba Cserép, Adam Denes, Balázs Pósfai, Nikolett Lénárt, Ákos Menyhárt, Ferenc Bari, Dániel Varga, Bernadett Martinecz
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism
J Cereb Blood Flow Metab
J Cereb Blood Flow Metab
Selective elimination of microglia from the brain was shown to dysregulate neuronal Ca2+ signaling and to reduce the incidence of spreading depolarization (SD) during cerebral ischemia. However, the mechanisms through which microglia interfere with S