Zobrazeno 1 - 10
of 284
pro vyhledávání: '"Balázs, Sarkadi"'
Autor:
Orsolya Mózner, Judit Moldvay, Kata Sára Szabó, Dorottya Vaskó, Júlia Domján, Dorottya Ács, Zoltán Ligeti, Csaba Fehér, Edit Hirsch, László Puskás, Cordula Stahl, Manfred Frey, Balázs Sarkadi
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3193 (2023)
We have developed a simple, rapid, high-throughput RBD-based ELISA to assess the humoral immunity against emerging SARS-CoV-2 virus variants. The cDNAs of the His-tagged RBD proteins of the virus variants were stably engineered into HEK cells secreti
Externí odkaz:
https://doaj.org/article/546b049f31c7434c94b9ec2bc1c8e371
Autor:
Orsolya Mózner, Boglárka Zámbó, Zsuzsa Bartos, Anna Gergely, Kata Sára Szabó, Bálint Jezsó, Ágnes Telbisz, György Várady, László Homolya, Tamás Hegedűs, Balázs Sarkadi
Publikováno v:
Membranes, Vol 13, Iss 10, p 822 (2023)
The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics, contributes to cancer drug resistance and the development of gout. In this work, we have analyzed the effects of selected variants, r
Externí odkaz:
https://doaj.org/article/d2e751a0cf98473c95d382c7980d6546
Autor:
Tamás Ferenci, Balázs Sarkadi
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Limited information is available on the effectiveness of the BBIBP-CorV (Sinopharm, Beijing CNBG) vaccine, especially in the elderly, despite the fact that it is approved in more than 50 countries. Methods RBD-specific antibody ti
Externí odkaz:
https://doaj.org/article/8d1b982bb0a04a3a99d510a1dc0d0553
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Transporters in the human liver play a major role in the clearance of endo- and xenobiotics. Apical (canalicular) transporters extrude compounds to the bile, while basolateral hepatocyte transporters promote the uptake of, or expel, various
Externí odkaz:
https://doaj.org/article/4ddf4cfaa6b9472a9a671a89aa7c8a37
Autor:
Edit Szabó, Anna Kulin, László Korányi, Botond Literáti-Nagy, Judit Cserepes, Anikó Somogyi, Balázs Sarkadi, György Várady
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Type 2 diabetes mellitus (T2DM) is one of the most common multifactorial diseases and several membrane transporters are involved in its development, complications and treatment. We have recently developed a flow-cytometry assay panel for the
Externí odkaz:
https://doaj.org/article/e5369ce45b044a7c819cf6b39c05aeb1
Autor:
Anna Kulin, Nóra Kucsma, Balázs Bohár, Botond Literáti-Nagy, László Korányi, Judit Cserepes, Anikó Somogyi, Balázs Sarkadi, Edit Szabó, György Várady
Publikováno v:
Biology, Vol 11, Iss 11, p 1669 (2022)
The human GLUT1 (SLC2A1) membrane protein is the key glucose transporter in numerous cell types, including red cells, kidney, and blood-brain barrier cells. The expression level of this protein has a role in several diseases, including cancer and Alz
Externí odkaz:
https://doaj.org/article/7b05fdae17d44e46b15a56baf3d63ca9
Autor:
Dóra Reé, Adrienn Borsy, Ábel Fóthi, Tamás I. Orbán, György Várady, Zsuzsa Erdei, Balázs Sarkadi, János Réthelyi, Nóra Varga, Ágota Apáti
Publikováno v:
Stem Cell Research, Vol 50, Iss , Pp 102134- (2021)
DiGeorge Syndrome (DGS) Critical Region 8 (DGCR8) is a primary candidate gene in they DGS. The DGCR8 microprocessor complex subunit is an essential cofactor in the canonical miRNA biogenesis which is involved in diverse cellular functions such as cel
Externí odkaz:
https://doaj.org/article/57acf6fad9ef48588c90213bab2b1f14
Autor:
Edit Szabó, Anna Kulin, Orsolya Mózner, László Korányi, Botond Literáti-Nagy, Márta Vitai, Judit Cserepes, Balázs Sarkadi, György Várady
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0260957 (2021)
Type 2 diabetes mellitus (T2DM) is a complex metabolic disease and variations in multispecific membrane transporter functions may affect T2DM development, complications or treatment. In this work we have analyzed the potential effects of a major poly
Externí odkaz:
https://doaj.org/article/d32775f11f4746248357adfa66a322ad
Autor:
Boglárka Zámbó, Zsuzsa Bartos, Orsolya Mózner, Edit Szabó, György Várady, Gyula Poór, Márton Pálinkás, Hajnalka Andrikovics, Tamás Hegedűs, László Homolya, Balázs Sarkadi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract The ABCG2 membrane protein is a key xeno- and endobiotic transporter, modulating the absorption and metabolism of pharmacological agents and causing multidrug resistance in cancer. ABCG2 is also involved in uric acid elimination and its impa
Externí odkaz:
https://doaj.org/article/985b89481f7e46d08466e8eaf2a472db
Autor:
Telbisz, Éva Bakos, Csilla Temesszentandrási-Ambrus, Csilla Özvegy-Laczka, Zsuzsanna Gáborik, Balázs Sarkadi, Ágnes
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 14; Pages: 11237
Orally administered small molecules may have important therapeutic potential in treating COVID-19 disease. The recently developed antiviral agents, Molnupiravir and Nirmatrelvir, have been reported to be efficient treatments, with only moderate side
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::1f0676f9dd77f7eda7d09ccbfb996925