Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Baktiar Karim"'
Autor:
Riley M. Larkin, Diana C. Lopez, Yvette L. Robbins, Wiem Lassoued, Kenneth Canubas, Andrew Warner, Baktiar Karim, Ksenia Vulikh, James W. Hodge, Charalampos S. Floudas, James L. Gulley, Gary L. Gallia, Clint T. Allen, Nyall R. London
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Olfactory neuroblastoma is a rare malignancy of the anterior skull base typically treated with surgery and adjuvant radiation. Although outcomes are fair for low-grade disease, patients with high-grade, recurrent, or metastatic di
Externí odkaz:
https://doaj.org/article/9c3008c5e18e402ebfcaa48b6b269fbc
Autor:
Sanghee Lim, Minhye Kwak, Jeonghan Kang, Melissa Cesaire, Kayen Tang, Robert W. Robey, William J. E. Frye, Baktiar Karim, Donna Butcher, Martin J. Lizak, Mahalia Dalmage, Brandon Foster, Nicholas Nuechterlein, Charles Eberhart, Patrick J. Cimino, Michael M. Gottesman, Sadhana Jackson
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-20 (2024)
Abstract In malignant glioma, cytotoxic drugs are often inhibited from accessing the tumor site due to the blood-tumor barrier (BTB). Ibrutinib, FDA-approved lymphoma agent, inhibits Bruton tyrosine kinase (BTK) and has previously been shown to indep
Externí odkaz:
https://doaj.org/article/e10420c2c7f8462fb3381665c144761c
Autor:
John A. Quinlan, Collin T. Inglut, Payal Srivastava, Idrisa Rahman, Jillian Stabile, Brandon Gaitan, Carla Arnau Del Valle, Kaylin Baumiller, Anandita Gaur, Wen‐An Chiou, Baktiar Karim, Nina Connolly, Robert W. Robey, Graeme F. Woodworth, Michael M. Gottesman, Huang‐Chiao Huang
Publikováno v:
Advanced Science, Vol 11, Iss 17, Pp n/a-n/a (2024)
Abstract Glioblastoma (GBM) is hard to treat due to cellular invasion into functioning brain tissues, limited drug delivery, and evolved treatment resistance. Recurrence is nearly universal even after surgery, chemotherapy, and radiation. Photodynami
Externí odkaz:
https://doaj.org/article/d233ac9e427242cd93a9e8dabf035622
Autor:
Arun Prakash Mishra, Suzanne Hartford, Rajani Kant Chittela, Sounak Sahu, Suhas S. Kharat, Lucia Alvaro-Aranda, Aida Contreras-Perez, Teresa Sullivan, Betty K. Martin, Mary Albaugh, Eileen Southon, Sandra Burkett, Baktiar Karim, Aura Carreira, Lino Tessarollo, Shyam K. Sharan
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-10 (2023)
Abstract Pathogenic variants in BRCA2 are known to significantly increase the lifetime risk of developing breast and ovarian cancers. Sequencing-based genetic testing has resulted in the identification of thousands of BRCA2 variants that are consider
Externí odkaz:
https://doaj.org/article/4d910d29476842d0a246d375382720ea
Autor:
Riley M. Larkin, Diana C. Lopez, Yvette L. Robbins, Wiem Lassoued, Kenneth Canubas, Andrew Warner, Baktiar Karim, Ksenia Vulikh, James W. Hodge, Charalampos S. Floudas, James L. Gulley, Gary L. Gallia, Clint T. Allen, Nyall R. London
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/7d7eee268c504f4a856af0a3556c3ff0
Autor:
Chiara Di Malta, Angela Zampelli, Letizia Granieri, Claudia Vilardo, Rossella De Cegli, Laura Cinque, Edoardo Nusco, Salvatore Pece, Daniela Tosoni, Francesca Sanguedolce, Nicolina Cristina Sorrentino, Maria J Merino, Deborah Nielsen, Ramaprasad Srinivasan, Mark W Ball, Christopher J Ricketts, Cathy D Vocke, Martin Lang, Baktiar Karim, Luisa Lanfrancone, Laura S Schmidt, W Marston Linehan, Andrea Ballabio
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 5, Pp 1-12 (2023)
Abstract Birt‐Hogg‐Dubé (BHD) syndrome is an inherited familial cancer syndrome characterized by the development of cutaneous lesions, pulmonary cysts, renal tumors and cysts and caused by loss‐of‐function pathogenic variants in the gene enc
Externí odkaz:
https://doaj.org/article/fc7292bb504a4e85bf4c9b3aa30dc3e3
Autor:
Ludmila Szabova, Melanie B. Gordon, Lucy Lu, Nathan Pate, Laura Bassel, Anthony J. Iacovelli, Baktiar Karim, Philip J. Homan, Deborah B. Householder, Theresa M. Guerin, Sandra Burkett, Amanda M. Day, Wendi Custer, Zoe Weaver Ohler
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-22 (2022)
Abstract Background Breast cancer is a heterogenous disease with several histological and molecular subtypes. Models that represent these subtypes are essential for translational research aimed at improving clinical strategy for targeted therapeutics
Externí odkaz:
https://doaj.org/article/249a300a5b844c129386a0e0e076f000
Autor:
Michal Mauda-Havakuk, Natalie M. Hawken, Joshua W. Owen, Andrew S. Mikhail, Ankit Saxena, Baktiar Karim, Paul G. Wakim, William F. Pritchard, John W. Karanian, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The immune response to radiofrequency ablation (RFA) and cryoablation (CRA) was characterized and compared in a colon cancer mouse model. All studies were conducted under a research protocol approved by the National Institutes of Health, Cli
Externí odkaz:
https://doaj.org/article/1b3f5f53145044b186cc82ab49b63fa9
Autor:
Yurong Song, Travis D. Kerr, Chelsea Sanders, Lisheng Dai, Shaneen S. Baxter, Brandon Somerville, Ryan N. Baugher, Stephanie D. Mellott, Todd B. Young, Heidi E. Lawhorn, Teri M. Plona, Bingfang Xu, Lei Wei, Qiang Hu, Song Liu, Alan Hutson, Baktiar Karim, Sandra Burkett, Simone Difilippantonio, Ligia Pinto, Johannes Gebert, Matthias Kloor, Steven M. Lipkin, Shizuko Sei, Robert H. Shoemaker
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundGenome integrity is essential for the survival of an organism. DNA mismatch repair (MMR) genes (e.g., MLH1, MSH2, MSH6, and PMS2) play a critical role in the DNA damage response pathway for genome integrity maintenance. Germline mutations o
Externí odkaz:
https://doaj.org/article/0d2e5d6b71eb4b909e5643961c4ff61e
Autor:
David Peeney, Yu Fan, Sadeechya Gurung, Carolyn Lazaroff, Shashikala Ratnayake, Andrew Warner, Baktiar Karim, Daoud Meerzaman, William G. Stetler-Stevenson
Publikováno v:
Matrix Biology Plus, Vol 18, Iss , Pp 100132- (2023)
Tissue inhibitor of metalloproteinases (TIMPs/Timps) are an endogenous family of widely expressed matrisome-associated proteins that were initially identified as inhibitors of matrix metalloproteinase activity (Metzincin family proteases). Consequent
Externí odkaz:
https://doaj.org/article/84c4f8d1102544889d01281b0de9087b