Efficacy of AAV8-h UGT1A1  with Rapamycin in neonatal, suckling, and juvenile rats to model treatment in pediatric CNs patients.

Autor: Shi X; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Meibergdreef 69-71, 1105 BK Amsterdam, the Netherlands., Aronson SJ; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Meibergdreef 69-71, 1105 BK Amsterdam, the Netherlands., Ten Bloemendaal L; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Meibergdreef 69-71, 1105 BK Amsterdam, the Netherlands., Duijst S; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Meibergdreef 69-71, 1105 BK Amsterdam, the Netherlands., Bakker RS; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Meibergdreef 69-71, 1105 BK Amsterdam, the Netherlands., de Waart DR; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Meibergdreef 69-71, 1105 BK Amsterdam, the Netherlands., Bortolussi G; International Centre for Genetic Engineering and Biotechnology, 34149 Trieste, Italy., Collaud F; Genethon, 91000 Evry, France.; Université Paris-Saclay, Université d'Evry, INSERM, Genethon, Integrare Research Unit UMR S951, 91000 Evry, France., Oude Elferink RP; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Meibergdreef 69-71, 1105 BK Amsterdam, the Netherlands., Muro AF; International Centre for Genetic Engineering and Biotechnology, 34149 Trieste, Italy., Mingozzi F; Genethon, 91000 Evry, France., Ronzitti G; Genethon, 91000 Evry, France.; Université Paris-Saclay, Université d'Evry, INSERM, Genethon, Integrare Research Unit UMR S951, 91000 Evry, France., Bosma PJ; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Meibergdreef 69-71, 1105 BK Amsterdam, the Netherlands.

Publikováno v: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2020 Dec 03; Vol. 20, pp. 287-297. Date of Electronic Publication: 2020 Dec 03 (Print Publication: 2021).

Liver-directed gene therapy results in long-term correction of progressive familial intrahepatic cholestasis type 3 in mice.

Autor: Aronson SJ; Amsterdam University Medical Centers, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Meibergdreef 9, Amsterdam, The Netherlands., Bakker RS; Amsterdam University Medical Centers, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Meibergdreef 9, Amsterdam, The Netherlands., Shi X; Amsterdam University Medical Centers, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Meibergdreef 9, Amsterdam, The Netherlands., Duijst S; Amsterdam University Medical Centers, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Meibergdreef 9, Amsterdam, The Netherlands., Ten Bloemendaal L; Amsterdam University Medical Centers, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Meibergdreef 9, Amsterdam, The Netherlands., de Waart DR; Amsterdam University Medical Centers, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Meibergdreef 9, Amsterdam, The Netherlands., Verheij J; Amsterdam University Medical Centers, University of Amsterdam, Department of Pathology, Meibergdreef 9, Amsterdam, The Netherlands., Ronzitti G; INTEGRARE, Genethon, INSERM, University of Evry, University Paris-Saclay, 91002 Evry, France., Oude Elferink RP; Amsterdam University Medical Centers, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Meibergdreef 9, Amsterdam, The Netherlands., Beuers U; Amsterdam University Medical Centers, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Meibergdreef 9, Amsterdam, The Netherlands., Paulusma CC; Amsterdam University Medical Centers, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Meibergdreef 9, Amsterdam, The Netherlands., Bosma PJ; Amsterdam University Medical Centers, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Meibergdreef 9, Amsterdam, The Netherlands. Electronic address: p.j.bosma@amc.uva.nl.

Publikováno v: Journal of hepatology [J Hepatol] 2019 Jul; Vol. 71 (1), pp. 153-162. Date of Electronic Publication: 2019 Mar 29.

Reference frames in the decisions of hand choice.

Autor: Bakker RS; Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen , Nijmegen , The Netherlands., Selen LPJ; Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen , Nijmegen , The Netherlands., Medendorp WP; Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen , Nijmegen , The Netherlands.

Publikováno v: Journal of neurophysiology [J Neurophysiol] 2018 May 01; Vol. 119 (5), pp. 1809-1817. Date of Electronic Publication: 2018 Feb 14.

Stability of Phase Relationships While Coordinating Arm Reaches with Whole Body Motion.

Autor: Bakker RS; Radboud University Nijmegen, Donders Centre for Cognition, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands., Selen LP; Radboud University Nijmegen, Donders Centre for Cognition, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands., Medendorp WP; Radboud University Nijmegen, Donders Centre for Cognition, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands.

Publikováno v: PloS one [PLoS One] 2015 Dec 31; Vol. 10 (12), pp. e0146231. Date of Electronic Publication: 2015 Dec 31 (Print Publication: 2015).