Body weight is negatively associated with direct oral anticoagulant trough concentrations in dabigatran and apixaban users.

Autor: Borst JM; Department of Hospital Care, Lairesse Pharmacy, Amsterdam, the Netherlands.; Department of Hospital Pharmacy, Haga Teaching Hospital, The Hague, the Netherlands., van Rein N; Department of Hospital Pharmacy, Haga Teaching Hospital, The Hague, the Netherlands.; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Bakker ECMD; Department of Hospital Pharmacy, Haga Teaching Hospital, The Hague, the Netherlands., Vukadin N; Department of Hospital Pharmacy, Haga Teaching Hospital, The Hague, the Netherlands., Rier M; Department of Cardiology, Haga Teaching Hospital, The Hague, the Netherlands., Mairuhu ATA; Department of Internal Medicine, Haga Teaching Hospital, The Hague, the Netherlands., Hudig F; Department of Clinical Chemistry, Haga Teaching Hospital, The Hague, the Netherlands., Bosma LBE; Department of Hospital Pharmacy, Haga Teaching Hospital, The Hague, the Netherlands., Wilms EB; Department of Hospital Pharmacy, Haga Teaching Hospital, The Hague, the Netherlands.; Laboratory, Central Hospital Pharmacy, The Hague, the Netherlands., Visser LE; Department of Hospital Pharmacy, Haga Teaching Hospital, The Hague, the Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.

Publikováno v: British journal of haematology [Br J Haematol] 2020 Dec; Vol. 191 (5), pp. 941-944. Date of Electronic Publication: 2020 Aug 01.