Development of novel HER2 inhibitors against gastric cancer derived from flavonoid source of Syzygium alternifolium through molecular dynamics and pharmacophore-based screening

Autor: Babu TMC, Rammohan A, Baki VB, Devi S, Gunasekar D, Rajendra W

Publikováno v: Drug Design, Development and Therapy, Vol Volume 10, Pp 3611-3632 (2016)

Tirumalasetty Muni Chandra Babu,1 Aluru Rammohan,2 Vijaya Bhaskar Baki,1 Savita Devi,3 Duvvuru Gunasekar,2 Wudayagiri Rajendra1 1Bioinformatics Center, Division of Molecular Biology, Department of Zoology, 2Natural Products Division, Department of Ch

Externí odkaz: https://doaj.org/article/05fc923150dc4b3c80c9f34b736e16d6

Liver matrin-3 protects mice against hepatic steatosis and stress response via constitutive androstane receptor.

Autor: Cheng X; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE 68588, USA., Baki VB; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE 68588, USA., Moran M; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE 68588, USA., Liu B; Department of Nutrition and Health Sciences, University of Nebraska - Lincoln, 230 Filley Hall, Lincoln, NE 68583-0922, USA., Yu J; Department of Nutrition and Health Sciences, University of Nebraska - Lincoln, 230 Filley Hall, Lincoln, NE 68583-0922, USA., Zhao M; Nebraska Center for Virology, School of Biological Sciences, University of Nebraska - Lincoln, Lincoln, NE, USA., Li Q; Nebraska Center for Virology, School of Biological Sciences, University of Nebraska - Lincoln, Lincoln, NE, USA., Riethoven JJ; Nebraska Center for Biotechnology, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE 68588, USA; Nebraska Center for Integrated Biomolecular Communication (NCIBC), University of Nebraska - Lincoln, Lincoln, NE 68588, USA., Gurumurth CB; Mouse Genome Engineering Core Facility, University of Nebraska Medical Center, Omaha, USA., Harris EN; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE 68588, USA; Nebraska Center for Integrated Biomolecular Communication (NCIBC), University of Nebraska - Lincoln, Lincoln, NE 68588, USA; Nebraska Center for the Prevention of Obesity Diseases through Dietary Molecules, University of Nebraska - Lincoln, USA., Sun X; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE 68588, USA; Nebraska Center for Integrated Biomolecular Communication (NCIBC), University of Nebraska - Lincoln, Lincoln, NE 68588, USA; Nebraska Center for the Prevention of Obesity Diseases through Dietary Molecules, University of Nebraska - Lincoln, USA. Electronic address: xsun17@unl.edu.

Publikováno v: Molecular metabolism [Mol Metab] 2024 Aug; Vol. 86, pp. 101977. Date of Electronic Publication: 2024 Jun 25.

Multifaceted roles of Meg3 in cellular senescence and atherosclerosis.

Autor: Cheng X; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE, 68588, USA., Shihabudeen Haider Ali MS; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE, 68588, USA., Baki VB; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE, 68588, USA., Moran M; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE, 68588, USA., Su H; Vascular Biology Center, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA; Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA., Sun X; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE, 68588, USA; Nebraska Center for the Prevention of Obesity Diseases Through Dietary Molecules, University of Nebraska - Lincoln, USA. Electronic address: xsun17@unl.edu.

Publikováno v: Atherosclerosis [Atherosclerosis] 2024 May; Vol. 392, pp. 117506. Date of Electronic Publication: 2024 Mar 08.

Synthesis and Anti-Pancreatic Cancer Activity Studies of Novel 3-Amino-2-hydroxybenzofused 2-Phospha-γ-lactones.

Autor: Balam SK; Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, India., Soora Harinath J; Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, India., Krishnammagari SK; Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, India., Gajjala RR; Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, India., Polireddy K; Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, Texas 77030, United States., Baki VB; Department of Pathophysiology, The Key Immunopathology Laboratory of Guangdong Province, Shantou University Medical College, Shantou 515031, Guangdong Province, China., Gu W; Department of Pathophysiology, The Key Immunopathology Laboratory of Guangdong Province, Shantou University Medical College, Shantou 515031, Guangdong Province, China., Valasani KR; Department of Pharmacology & Toxicology and Higuchi Bioscience Center, School of Pharmacy, University of Kansas, Lawrence, Kansas 66047, United States., Avula VKR; Chemical Engineering Institute, Ural Federal University, Yekaterinburg 620002, Russian Federation., Vallela S; Chemical Engineering Institute, Ural Federal University, Yekaterinburg 620002, Russian Federation., Zyryanov GV; Chemical Engineering Institute, Ural Federal University, Yekaterinburg 620002, Russian Federation.; Ural Division of the Russian Academy of Sciences, I. Ya. Postovskiy Institute of Organic Synthesis, 22 S. Kovalevskoy Street, Yekaterinburg 620219, Russian Federation., Pasupuleti VR; Department of Biomedical Sciences and Therapeutics, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu 88400, Sabah, Malaysia.; Department of Biochemistry, Faculty of Medicine and Health Sciences, Abdurrab University, Jl Riau Ujung No. 73, Pekanbaru 28292, Riau, Indonesia., Cirandur SR; Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, India.

Publikováno v: ACS omega [ACS Omega] 2021 Apr 23; Vol. 6 (17), pp. 11375-11388. Date of Electronic Publication: 2021 Apr 23 (Print Publication: 2021).