Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Bakhyt T. Matkarimov"'
Publikováno v:
PeerJ, Vol 11, p e16671 (2023)
Background Francis Crick’s central dogma provides a residue-by-residue mechanistic explanation of the flow of genetic information in living systems. However, this principle may not be sufficient for explaining how random mutations cause continuous
Externí odkaz:
https://doaj.org/article/ebd6f588827144bd958b31e8bffa5f1b
Autor:
Mikhail Yu. Lobanov, Leonid B. Pereyaslavets, Ilya V. Likhachev, Bakhyt T. Matkarimov, Oxana V. Galzitskaya
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 5960-5968 (2021)
The aim of this study was to evaluate the favorability of different conformations of aromatic residues in proteins by analysing the occurrence of particular conformations. The clustering of protein structures from the Protein Data Bank (PDB) was perf
Externí odkaz:
https://doaj.org/article/446e6f61aad0401e93e34ed10df033fd
Autor:
Andrey A. Yurchenko, Ismael Padioleau, Bakhyt T. Matkarimov, Jean Soulier, Alain Sarasin, Sergey Nikolaev
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Xeroderma Pigmentosum group C (XP-C) is a rare genetic disorder characterised by deficient DNA repair leading to skin and internal cancer, but the latter is not well understood molecularly. Here the authors sequence genomes of non-skin cancers from X
Externí odkaz:
https://doaj.org/article/486d5c1a2f994c9e87d502eb64b048d7
Autor:
Manideep C. Pachva, Alexei F. Kisselev, Bakhyt T. Matkarimov, Murat Saparbaev, Regina Groisman
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The nucleosome is a stretch of DNA wrapped around a histone octamer. Electrostatic interactions and hydrogen bonds between histones and DNA are vital for the stable organization of nucleosome core particles, and for the folding of chromatin into more
Externí odkaz:
https://doaj.org/article/2abc33f9fb3b446bb88aee0b291611af
Autor:
Paulina Prorok, Inga R. Grin, Bakhyt T. Matkarimov, Alexander A. Ishchenko, Jacques Laval, Dmitry O. Zharkov, Murat Saparbaev
Publikováno v:
Cells, Vol 10, Iss 7, p 1591 (2021)
It was proposed that the last universal common ancestor (LUCA) evolved under high temperatures in an oxygen-free environment, similar to those found in deep-sea vents and on volcanic slopes. Therefore, spontaneous DNA decay, such as base loss and cyt
Externí odkaz:
https://doaj.org/article/43bea6ab572d47bdbdabbccb8ba0d5c6
Autor:
Caroline Zutterling, Aibek Mursalimov, Ibtissam Talhaoui, Zhanat Koshenov, Zhiger Akishev, Amangeldy K. Bissenbaev, Gerard Mazon, Nicolas E. Geacintov, Didier Gasparutto, Regina Groisman, Dmitry O. Zharkov, Bakhyt T. Matkarimov, Murat Saparbaev
Publikováno v:
PeerJ, Vol 6, p e6029 (2018)
Background DNA repair is essential to counteract damage to DNA induced by endo- and exogenous factors, to maintain genome stability. However, challenges to the faithful discrimination between damaged and non-damaged DNA strands do exist, such as mism
Externí odkaz:
https://doaj.org/article/1b7cbd52f22e4528b2fe6b110d3bd63d
Autor:
Jean Soulier, Alain Sarasin, Ismael Padioleau, Andrey A. Yurchenko, Bakhyt T. Matkarimov, Sergey Nikolaev
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Recent studies demonstrated a dramatically increased risk of leukemia in patients with a rare genetic disorder, Xeroderma Pigmentosum group C (XP-C), characterized by constitutive deficiency of global genome nucleotide excision repair (GG-NER). The g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffce1ef6d3ff6a9db79ece7ca4e4a8d9
http://link.springer.com/article/10.1038/s41467-020-19633-9
http://link.springer.com/article/10.1038/s41467-020-19633-9
Autor:
Murat Saparbaev, Bakhyt T. Matkarimov, Regina Groisman, Inga R. Grin, Antonina P. Dvornikova, Dmitry O. Zharkov, Alexander V. Popov
Publikováno v:
Journal of Molecular Biology. 432:1747-1768
Base excision DNA repair (BER) is an important process used by all living organisms to remove nonbulky lesions from DNA. BER is usually initiated by DNA glycosylases that excise a damaged base leaving an apurinic/apyrimidinic (AP) site, and an AP end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711e94422d6f15ac55bacc71e5051604
https://doi.org/10.1016/j.jmb.2019.12.020
https://doi.org/10.1016/j.jmb.2019.12.020
Autor:
Alexander A. Ishchenko, Bakhyt T. Matkarimov, Assel Kiribayeva, Bekbolat Khassenov, Elie Matta
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-60631-0⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-60631-0⟩
DNA-dependent poly(ADP-ribose) polymerases (PARPs) PARP1, PARP2 and PARP3 act as DNA break sensors signalling DNA damage. Upon detecting DNA damage, these PARPs use nicotine adenine dinucleotide as a substrate to synthesise a monomer or polymer of AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee9c9bb1a6b1d20e79e8ab4af91bb54
http://link.springer.com/article/10.1038/s41598-020-60631-0
http://link.springer.com/article/10.1038/s41598-020-60631-0