Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Bakhtiyor Yakubov"'
Autor:
Jiyoon Lee, Bakhtiyor Yakubov, Cristina Ivan, David R. Jones, Andrea Caperell-Grant, Melissa Fishel, Horacio Cardenas, Daniela Matei
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 11, Pp 689-698 (2016)
Resistance to chemotherapy is a hallmark of pancreatic ductal adenocarcinoma (PDA) and has been partly attributed to the dense desmoplastic stroma, which forms a protective niche for cancer cells. Tissue transglutaminase (TG2), a Ca2+-dependent enzym
Externí odkaz:
https://doaj.org/article/ddfa8102ae784a41b77ad599e164f02b
Autor:
Bakhtiyor Yakubov, Bhadrani Chelladurai, Jordan Schmitt, Robert Emerson, John J. Turchi, Daniela Matei
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 6, Pp 609-619 (2013)
Tissue transglutaminase (TG2) is a multifunctional protein that binds to fibronectin and exerts protein transamidating activity in the presence of Ca2+. We previously reported that TG2 is upregulated in ovarian tumors and enhances intraperitoneal (i.
Externí odkaz:
https://doaj.org/article/8064ecb2fcce4ceb85f7b147298cd55e
Autor:
Andrea Lee Frump, Margie Albrecht, Sandra Breuils-Bonnet, Bakhtiyor Yakubov, Mary Beth Brown, Steeve Provencher, Sebastien Bonnet, Tim Lahm
Publikováno v:
Journal of Clinical and Translational Science, Vol 1, Pp 60-60 (2017)
OBJECTIVES/SPECIFIC AIMS: Women with pulmonary arterial hypertension (PAH) exhibit superior right ventricular (RV) function and survival compared with men, a phenomenon attributed to poorly understood cardioprotective effects of 17β-estradiol (E2).
Externí odkaz:
https://doaj.org/article/599e97b9991f4b25bf6570a9055edbeb
Autor:
Bakhtiyor Yakubov, Lan Chen, Alexey M Belkin, Sheng Zhang, Bhadrani Chelladurai, Zhong-Yin Zhang, Daniela Matei
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89285 (2014)
Tissue transglutaminase (TG2) mediates protein crosslinking through generation of ε-(γ-glutamyl) lysine isopeptide bonds and promotes cell adhesion through interaction with fibronectin (FN) and integrins. Cell adhesion to the peritoneal matrix regu
Externí odkaz:
https://doaj.org/article/0b0089e8a4af41a6a297290fe1fc4e5e
Autor:
Andrea L. Frump, Bakhtiyor Yakubov, Avram Walts, Amanda Fisher, Todd Cook, Naomi C. Chesler, Tim Lahm
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 68:341-344
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::577e8f3f2ce3c0f9acdacad79500437c
https://doi.org/10.1165/rcmb.2022-0224le
https://doi.org/10.1165/rcmb.2022-0224le
Autor:
Daniela Matei, Zhong-Yin Zhang, Constandina Arvanitis, Gary E. Schiltz, Lan Chen, Nkechiyere G. Nwani, Arabela A. Grigorescu, Salvatore Condello, Sheng Zhang, Bakhtiyor Yakubov, Livia Elena Sima
Materials, methods; Figure S1. 1H NMR spectrum of MT-1; Figure S2. 1H NMR spectrum of MT-2; Figure S3. 1H NMR spectrum of MT-3; Figure S4. 1H NMR spectrum of MT-4; Figure S5. 1H NMR spectrum of MT-5; Figure S6. 1H NMR spectrum of MT-6; Figure S7. Ent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e12d28746f00e635fcc5260dbb111a4
https://doi.org/10.1158/1535-7163.22505841
https://doi.org/10.1158/1535-7163.22505841
Autor:
Daniela Matei, Zhong-Yin Zhang, Constandina Arvanitis, Gary E. Schiltz, Lan Chen, Nkechiyere G. Nwani, Arabela A. Grigorescu, Salvatore Condello, Sheng Zhang, Bakhtiyor Yakubov, Livia Elena Sima
Tissue transglutaminase (TG2) is a multifunctional protein with enzymatic, GTP-ase, and scaffold properties. TG2 interacts with fibronectin (FN) through its N-terminus domain, stabilizing integrin complexes, which regulate cell adhesion to the matrix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56053471ec81d270f699ecb855dec8b2
https://doi.org/10.1158/1535-7163.c.6538218.v1
https://doi.org/10.1158/1535-7163.c.6538218.v1
Autor:
Daniela Matei, Jingwu Xie, Kiyotaka Hitomi, Andrea Caperell-Grant, Robert Emerson, Bakhtiyor Yakubov, Salvatore Condello, Jiyoon Lee
Supplementary Figure 3. Effect of TG2 knockdown on PDA cell proliferation and colony formation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd1f326b8e959bbc169b906670fb450
https://doi.org/10.1158/1078-0432.22458710
https://doi.org/10.1158/1078-0432.22458710
Autor:
Daniela Matei, Jingwu Xie, Kiyotaka Hitomi, Andrea Caperell-Grant, Robert Emerson, Bakhtiyor Yakubov, Salvatore Condello, Jiyoon Lee
Supplementary Table 1. Clinical Characteristics of PDA specimens.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519a4b3b91856f64afd8317f29af5b43
https://doi.org/10.1158/1078-0432.22458698
https://doi.org/10.1158/1078-0432.22458698
Autor:
Daniela Matei, Jingwu Xie, Kiyotaka Hitomi, Andrea Caperell-Grant, Robert Emerson, Bakhtiyor Yakubov, Salvatore Condello, Jiyoon Lee
Supplementary Figure 1. Enzymatic activity of TG2 in PDA cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b92096c4d6333d391032fdbf55debcc
https://doi.org/10.1158/1078-0432.22458716
https://doi.org/10.1158/1078-0432.22458716