Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bakhtiyor F, Rasulev"'
Publikováno v:
Molecules, Vol 9, Iss 12, Pp 1194-1207 (2004)
A QSAR toxicity analysis has been performed for a series of 19 alkaloids with the lycoctonine skeleton. GA-MLRA (Genetic Algorithm combined with Multiple Linear Regression Analysis) technique was applied for the generation of two types of QSARs: firs
Externí odkaz:
https://doaj.org/article/41401a95c02545709774724ca5258031
Publikováno v:
Chemical Physics Letters. 457:332-336
Autor:
Malakhat A, Turabekova, Valentina I, Vinogradova, Karl A, Werbovetz, Jeffrey, Capers, Bakhtiyor F, Rasulev, Mikhail G, Levkovich, Shukhrat B, Rakhimov, Nasrulla D, Abdullaev
Publikováno v:
Chemical biologydrug design. 78(1)
In vitro leishmanicidal activity of 16 N-benzylcytisine derivatives has been evaluated using Leishmania donovani axenic amastigotes. In general, halogen (bromo-, chloro-) derivatives appeared to be more toxic against parasites than their parent compo
Publikováno v:
Environmental toxicology and pharmacology. 25(3)
Large series of Aconitum and Delphinium alkaloids have been investigated by means of QSAR analysis. Descriptors related to "drug-likeness" of molecules were selected to discriminate between "drugs" and "non-drugs" amongst diterpenoid alkaloids of int