Zobrazeno 1 - 10
of 5 866
pro vyhledávání: '"Baker, Michael A."'
While the classical function of human mineralocorticoid receptor (MR) is to regulate sodium and potassium homeostasis through aldosterone activation of the kidney MR, the MR also is highly expressed in the brain, where the MR is activated by cortisol
Externí odkaz:
http://arxiv.org/abs/2412.04674
In this paper we generalize the technique of deflation to define two new methods to systematically find many local minima of a nonlinear least squares problem. The methods are based on the Gauss-Newton algorithm, and as such do not require the calcul
Externí odkaz:
http://arxiv.org/abs/2409.14438
We investigate a class of leptogenesis scenarios in which the sector containing the lightest right-handed neutrino establishes kinetic equilibrium at a temperature $T_{N_1} > T_\text{SM}$, where $T_\text{SM}$ is the temperature of the Standard Model
Externí odkaz:
http://arxiv.org/abs/2409.09113
An explicit quantization of Chern-Simons theory leads to an identity between sums of the Kac-Weyl characters. One can use this identity to prove inequalities that constrain the fusion coefficients $N_{\mu\nu}^l$ in the case of RCFTs that descend from
Externí odkaz:
http://arxiv.org/abs/2408.09257
We study a simplified model of two colourless heavy vector resonances in the singlet representation of $SU(2)_{L}$, with zero and unit hypercharge. We discuss mixing with the Standard Model gauge bosons due to electroweak symmetry breaking, semi-anal
Externí odkaz:
http://arxiv.org/abs/2407.11117
Due to alternative splicing in an ancestral DNA-binding domain (DBD) of the mineralocorticoid receptor (MR), humans contain two almost identical MR transcripts with either 984 amino acids (MR-984) or 988 amino acids (MR-988), in which their DBDs diff
Externí odkaz:
http://arxiv.org/abs/2405.10432
Five distinct full-length mineralocorticoid receptor (MR) genes have been identified in humans. These human MRs can be distinguished by the presence or absence of an in-frame insertion of 12 base pairs coding for Lys, Cys, Ser, Trp (KCSW) in their DN
Externí odkaz:
http://arxiv.org/abs/2312.05396
Autor:
Sevior, Martin, Baker, Michael, Bignell, Lindsey, Curceanu, Catalina, Dowie, Jackson T. H., Kibedi, Tibor, Jamieson, David, Stuchbery, Andrew, Thamm, Andrea, White, Martin
We propose a new Time Projection Chamber particle detector (TPC) to search for the existence of feebly-interacting bosons and to investigate the existence of the X17 boson, proposed by the ATOMKI group to explain anomalous results in the angular dist
Externí odkaz:
http://arxiv.org/abs/2302.13281
Atlantic sea lamprey contains two corticoid receptors (CRs), CR1 and CR2, that are identical except for a four amino acid insert (Thr-Arg-Gln-Gly) in the CR1 DNA-binding domain (DBD). Steroids are stronger transcriptional activators of CR2 than of CR
Externí odkaz:
http://arxiv.org/abs/2302.13162
Autor:
Katsu, Yoshinao, Lin, Xiaozhi, Ji, Ruigeng, Chen, Ze, Kamisaka, Yui, Bamba, Koto, Baker, Michael E.
Lampreys are jawless fish that evolved about 550 million years ago at the base of the vertebrate line. Modern lampreys contain a corticoid receptor (CR), the common ancestor of the glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), whi
Externí odkaz:
http://arxiv.org/abs/2210.04111