Výsledky vyhledávání - "Baker, Kenneth M."

Dissertation/ Thesis

Gastrin-Mediated Activation of Cyclin D1 Transcription Involves β-Catenin and Creb Pathways in Gastric Cancer Cells

Autor: Pradeep, Anamika, Sharma, Chandan, Sathyanarayana, Pradeep, Albanese, Chris, Fleming, John V., Wang, Timothy C., Wolfe, M. Michael, Baker, Kenneth M., Pestell, Richard, Rana, Basabi

Publikováno v: ETSU Faculty Works.

Gastrin and its precursors promote proliferation in different gastrointestinal cells. Since mature, amidated gastrin (G-17) can induce cyclin D1, we determined whether G-17-mediated induction of cyclin D1 transcription involved Wnt signaling and CRE-

Externí odkaz: https://dc.etsu.edu/etsu-works/18696

Zobrazit plný text záznamu

Dissertation/ Thesis

High-Glucose-Induced Regulation of Intracellular ANG II Synthesis and Nuclear Redistribution in Cardiac Myocytes

Autor: Singh, Vivek P., Le, Bao, Bhat, Vadiraja B., Baker, Kenneth M., Kumar, Rajesh

Publikováno v: ETSU Faculty Works.

The prevailing paradigm is that cardiac ANG II is synthesized in the extracellular space from components of the circulating and/or local renin-angiotensin system. The recent discovery of intracrine effects of ANG II led us to determine whether ANG II

Externí odkaz: https://dc.etsu.edu/etsu-works/17788

Zobrazit plný text záznamu

Dissertation/ Thesis

Activation of the Intracellular Renin-Angiotensin System in Cardiac Fibroblasts by High Glucose: Role in Extracellular Matrix Production

Autor: Singh, Vivek, Baker, Kenneth M., Kumar, Rajesh

Publikováno v: ETSU Faculty Works.

The occurrence of a functional intracellular renin-angiotensin system (RAS) has emerged as a new paradigm. Recently, we and others demonstrated intracellular synthesis of ANG II in cardiac myocytes and vascular smooth muscle cells that was dramatical

Externí odkaz: https://dc.etsu.edu/etsu-works/17547

Zobrazit plný text záznamu