Epstein-Barr virus down-regulates tumor suppressor DOK1 expression.

Autor: Maha Siouda, Cecilia Frecha, Rosita Accardi, Jiping Yue, Cyrille Cuenin, Henri Gruffat, Evelyne Manet, Zdenko Herceg, Bakary S Sylla, Massimo Tommasino

Publikováno v: PLoS Pathogens, Vol 10, Iss 5, p e1004125 (2014)

The DOK1 tumor suppressor gene encodes an adapter protein that acts as a negative regulator of several signaling pathways. We have previously reported that DOK1 expression is up-regulated upon cellular stress, via the transcription factor E2F1, and d

Externí odkaz: https://doaj.org/article/e6e18cb857244a5ea9da090b3c3287f5

Human Papillomavirus infection in senegalese female sex workers

Autor: Coumba Toure Kane, Cheikh Saad Bouh Boye, Halimatou Diop-Ndiaye, Sandrine McKay-Chopin, Tarik Gheit, Kaylin Beiter, Bakary S. Sylla, Aissatou Sow Ndoye, Aboubacry Dramé, Massimo Tommasino

Publikováno v: Papillomavirus Research
Papillomavirus Research, Vol 7, Iss, Pp 97-101 (2019)

Objectives: Several studies have documented the HPV genotypes in the Senegalese general population. The objective was to explore the HPV genotype distribution in Senegalese FSWs in order to assess the potential relevance of currently-available vaccin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522264a1ff09f88f8c2de982a039848c
https://pubmed.ncbi.nlm.nih.gov/30771492

In vitro transformation of primary human hepatocytes: Epigenetic changes and stemness properties

Autor: Philippe Merle, Davide Degli-Esposti, Claude Caron de Fromentel, Maud Michelet, Patricia Gifu, Bakary S. Sylla, Anaïs Lopez, Floriane Pez, Nadim Fares, Zdenko Herceg, Lydie Lefrançois, Brigitte Bancel, Michel Rivoire

Publikováno v: Experimental Cell Research
Experimental Cell Research, Elsevier, 2019, 384, pp.111643-. ⟨10.1016/j.yexcr.2019.111643⟩

Human hepatocarcinogenesis is a complex process with many unresolved issues, including the cell of origin (differentiated and/or progenitor/stem cells) and the initial steps leading to tumor development. With the aim of providing new tools for studyi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a94128130d290f5ec1e0296bb5df31
https://doi.org/10.1016/j.yexcr.2019.111643

Human papillomavirus infection in women in four regions of Senegal

Autor: Bakary S. Sylla, Massimo Tommasino, Ndeye Coumba Toure-Kane, Ahmadou Dem, Tarik Gheit, Souleymane Mboup, Sandrine McKay-Chopin, Cheikh Saad Bouh Boye, El Hadji Seydou Mbaye

Publikováno v: Journal of Medical Virology. 86:248-256

Cervical cancer is the most frequent cancer among women in Senegal. However, there are few data concerning the human papillomavirus (HPV) types inducing neoplasia and cervical cancers and their prevalence in the general population of Senegal. The aim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::810a433d00df62b08176a23726078fef
https://doi.org/10.1002/jmv.23719

The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter

Autor: Joyce Taylor-Papadimitriou, Uzma Hasan, Christine Carreira, Marine Malfroy, Nadège Goutagny, Peggy Parroche, Claudia Zannetti, Giorgio Trinchieri, Didier Picard, Martin Müller, Guillaume Roblot, Ishraq Hussain, Ruslan Medzhitov, Massimo Tommasino, Bakary S. Sylla

Publikováno v: The Journal of experimental medicine
The Journal of Experimental Medicine
Journal of Experimental Medicine, Vol. 210, No 7 (2013) pp. 1369-87

HPV16-positive cervical cancer lesions contain NFκB–ERα nuclear complexes to repress the TLR9 promoter.
Human papillomavirus type 16 (HPV16) and other oncogenic viruses have been reported to deregulate immunity by suppressing the function of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09bf0ccad010abafcdcee8ada63afb90