Charge-Reversed Exosomes for Targeted Gene Delivery to Cartilage for Osteoarthritis Treatment.

Autor: Zhang C; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA., Pathrikar TV; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA., Baby HM; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA., Li J; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, IL, 60612, USA., Zhang H; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA., Selvadoss A; Department of Chemical Engineering, Northeastern University, Boston, MA, 02115, USA., Ovchinnikova A; Department of Biology, Northeastern University, Boston, MA, 02115, USA., Ionescu A; Department of Biology, Northeastern University, Boston, MA, 02115, USA., Chubinskaya S; Department of Pediatrics, Rush University Medical College, Chicago, IL, 60612, USA., Miller RE; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, IL, 60612, USA., Bajpayee AG; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA.; Department of Chemical Engineering, Northeastern University, Boston, MA, 02115, USA.

Publikováno v: Small methods [Small Methods] 2024 Sep; Vol. 8 (9), pp. e2301443. Date of Electronic Publication: 2024 Apr 12.

Cationic-motif-modified exosomes for mRNA delivery to retinal photoreceptors.

Autor: Millán Cotto HA; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu., Pathrikar TV; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu., Hakim B; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu., Baby HM; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu., Zhang H; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu., Zhao P; Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA. pe.zhao@northeastern.edu., Ansaripour R; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu., Amini R; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu.; Department of Mechanical and Industrial Engineering, Northeastern University, Boston, MA 02115, USA., Carrier RL; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu.; Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA. pe.zhao@northeastern.edu., Bajpayee AG; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu.; Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA. pe.zhao@northeastern.edu.; Department of Mechanical and Industrial Engineering, Northeastern University, Boston, MA 02115, USA.

Publikováno v: Journal of materials chemistry. B [J Mater Chem B] 2024 Jul 31; Vol. 12 (30), pp. 7384-7400. Date of Electronic Publication: 2024 Jul 31.

Sustained intra-cartilage delivery of interleukin-1 receptor antagonist using cationic peptide and protein-based carriers.

Autor: Mehta S; Department of Bioengineering, Northeastern University, Boston, MA, USA. Electronic address: mehta.shi@northeastern.edu., Boyer TL; Department of Bioengineering, Northeastern University, Boston, MA, USA. Electronic address: boyer.t@northeastern.edu., Akhtar S; Department of Biochemistry, Northeastern University, Boston, MA, USA. Electronic address: akhtar.su@northeastern.edu., He T; Department of Bioengineering, Northeastern University, Boston, MA, USA. Electronic address: he.te@northeastern.edu., Zhang C; Department of Bioengineering, Northeastern University, Boston, MA, USA. Electronic address: zhang.chenz@northeastern.edu., Vedadghavami A; Department of Bioengineering, Northeastern University, Boston, MA, USA. Electronic address: vedadghavami.a@northeastern.edu., Bajpayee AG; Department of Bioengineering, Northeastern University, Boston, MA, USA; Department of Mechanical Engineering, Northeastern University, Boston, MA, USA. Electronic address: a.bajpayee@neu.edu.

Publikováno v: Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2023 Jun; Vol. 31 (6), pp. 780-792. Date of Electronic Publication: 2023 Feb 03.

Intra-articular kinetics of a cartilage targeting cationic PEGylated protein for applications in drug delivery.

Autor: He T; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA. Electronic address: he.te@northeastern.edu., Zhang C; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA. Electronic address: zhang.chenz@northeastern.edu., Colombani T; Department of Chemical Engineering, Northeastern University, Boston, MA, 02115, USA. Electronic address: t.colombani@northeastern.edu., Bencherif SA; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA; Department of Chemical Engineering, Northeastern University, Boston, MA, 02115, USA. Electronic address: s.bencherif@northeastern.edu., Porter RM; Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA; Department of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA. Electronic address: rmporter@uams.edu., Bajpayee AG; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA; Department of Mechanical Engineering, Northeastern University, Boston, MA, 02115, USA. Electronic address: a.bajpayee@northeastern.edu.

Publikováno v: Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2023 Feb; Vol. 31 (2), pp. 187-198. Date of Electronic Publication: 2022 Oct 12.

Modeling Electrostatic Charge Shielding Induced by Cationic Drug Carriers in Articular Cartilage Using Donnan Osmotic Theory.

Autor: Warren MR; Department of Bioengineering and Northeastern University, Boston, Massachusetts, USA., Bajpayee AG; Department of Bioengineering and Northeastern University, Boston, Massachusetts, USA.; Department of Mechanical Engineering, Northeastern University, Boston, Massachusetts, USA.

Publikováno v: Bioelectricity [Bioelectricity] 2022 Dec 01; Vol. 4 (4), pp. 248-258. Date of Electronic Publication: 2022 Dec 15.