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Akademický článek

Perioperative considerations in nonagenarians

Autor: Maria E. Tecos, MD, Brittany S. Kern, MD, Nathan A. Foje, MD, Marilyn L. Leif, Mitchell Schmidt, MD, Allie Steinberger, MD, Adam Bajinting, Keely L. Buesing, MD, FACS

Publikováno v: Surgery Open Science, Vol 2, Iss 4, Pp 45-49 (2020)

Objective: The nation's aging population presents novel perioperative challenges. Potential benefits of operative interventions must be scrutinized in relation to recoverable quality of life. The purpose of this study is to evaluate common risk calcu

Externí odkaz: https://doaj.org/article/c00a6dcfdcff4a6d9213ce9dff83f8c7

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Akademický článek

Single-Cell Analysis Reveals Regional Reprogramming During Adaptation to Massive Small Bowel Resection in Mice

Autor: Seiler, Kristen M., Waye, Sarah E., Kong, Wenjun, Kamimoto, Kenji, Bajinting, Adam, Goo, William H., Onufer, Emily J., Courtney, Cathleen, Guo, Jun, Warner, Brad W., Morris, Samantha A.

Publikováno v: In Cellular and Molecular Gastroenterology and Hepatology 2019 8(3):407-426

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Akademický článek

Single-Cell Analysis Reveals Regional Reprogramming During Adaptation to Massive Small Bowel Resection in MiceSummary

Autor: Kristen M. Seiler, Sarah E. Waye, Wenjun Kong, Kenji Kamimoto, Adam Bajinting, William H. Goo, Emily J. Onufer, Cathleen Courtney, Jun Guo, Brad W. Warner, Samantha A. Morris

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 3, Pp 407-426 (2019)

Background & Aims: The small intestine (SI) displays regionality in nutrient and immunological function. Following SI tissue loss (as occurs in short gut syndrome, or SGS), remaining SI must compensate, or “adapt”; the capacity of SI epithelium t

Externí odkaz: https://doaj.org/article/f1b4e01318da43e0baba97df780a42b8

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Akademický článek

Antibiotic-driven intestinal dysbiosis in pediatric short bowel syndrome is associated with persistently altered microbiome functions and gut-derived bloodstream infections

Autor: Robert Thänert, Anna Thänert, Jocelyn Ou, Adam Bajinting, Carey-Ann D. Burnham, Holly J. Engelstad, Maria E. Tecos, I. Malick Ndao, Carla Hall-Moore, Colleen Rouggly-Nickless, Mike A. Carl, Deborah C. Rubin, Nicholas O. Davidson, Phillip I. Tarr, Barbara B. Warner, Gautam Dantas, Brad W. Warner

Publikováno v: Gut Microbes, Vol 13, Iss 1 (2021)

Surgical removal of the intestine, lifesaving in catastrophic gastrointestinal disorders of infancy, can result in a form of intestinal failure known as short bowel syndrome (SBS). Bloodstream infections (BSIs) are a major challenge in pediatric SBS

Externí odkaz: https://doaj.org/article/34e2a30a876a42fbb17b0150d61db8e2

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Akademický článek

EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis.

Autor: Emily J Onufer, Bola Aladegbami, Toru Imai, Kristen Seiler, Adam Bajinting, Cathleen Courtney, Stephanie Sutton, Aiza Bustos, Junjie Yao, Cheng-Hung Yeh, Anne Sescleifer, Lihong V Wang, Jun Guo, Brad W Warner

Publikováno v: PLoS ONE, Vol 15, Iss 9, p e0236964 (2020)

BackgroundShort bowel syndrome (SBS) results from significant loss of small intestinal length. In response to this loss, adaptation occurs, with Epidermal Growth Factor Receptor (EGFR) being a key driver. Besides enhanced enterocyte proliferation, we

Externí odkaz: https://doaj.org/article/f0c162da93094ad695360c0e8b470eea

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Akademický článek

A Detailed Protocol for Large-scale Recombinant Expression and Validation of Human FGFR2 with Its Transmembrane and Extracellular Domains in Escherichia coli

Autor: Adam Bajinting, Ho Ng

Publikováno v: Bio-Protocol, Vol 9, Iss 11 (2019)

Receptor tyrosine kinases (RTKs) are an important class of transmembrane receptors that mediate some of the most crucial biochemical pathways essential to the growth, differentiation, and survival of a cell and thus, are highly involved in cancers. D

Externí odkaz: https://doaj.org/article/e080f743a2bb4a88bc52e0f87259cae0

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