Pirfenidone release from ophthalmic implants – perspectives for a drug-eluting microstent for glaucoma therapy

Autor: Reske Thomas, Stahnke Thomas, Bajer Dalibor, Grabow Niels, Khaimov Valeria, Guthoff Rudolf F., Schmitz Klaus-Peter, Siewert Stefan

Publikováno v: Current Directions in Biomedical Engineering, Vol 9, Iss 1, Pp 399-402 (2023)

Elevated intraocular pressure is the main risk factor for glaucoma and its adjustment to physiological levels can prevent progression of the disease. If conventional drop-based glaucoma therapy fails, surgical interventions such as trabeculectomy or

Externí odkaz: https://doaj.org/article/2e3d3ed7922d4f3785d0659da7ec8790

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Influence of Drug Incorporation on the Physico-Chemical Properties of Poly(l-Lactide) Implant Coating Matrices—A Systematic Study

Autor: Arbeiter, Daniela, Reske, Thomas, Teske, Michael, Bajer, Dalibor, Senz, Volkmar, Schmitz, Klaus-Peter, Grabow, Niels, Oschatz, Stefan

Publikováno v: Polymers
Volume 13
Issue 2
Polymers, Vol 13, Iss 292, p 292 (2021)

Local drug delivery has become indispensable in biomedical engineering with stents being ideal carrier platforms. While local drug release is superior to systemic administration in many fields, the incorporation of drugs into polymers may influence t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::270414bf6aa5db81392ea34472cefaf0

In Vitro Corrosion of Polyester-Coated Magnesium Alloy under pH-Static Conditions.

Autor: Fiedler N; Institute for Biomedical Engineering, Rostock University Medical Center, Friedrich-Barnewitz-Straße 4, 18119 Rostock, Germany., Teske M; Institute for Biomedical Engineering, Rostock University Medical Center, Friedrich-Barnewitz-Straße 4, 18119 Rostock, Germany., Nelz SC; Institute for Biomedical Engineering, Rostock University Medical Center, Friedrich-Barnewitz-Straße 4, 18119 Rostock, Germany., Flügge JW; Institute for Biomedical Engineering, Rostock University Medical Center, Friedrich-Barnewitz-Straße 4, 18119 Rostock, Germany., Senz V; Institute for Biomedical Engineering, Rostock University Medical Center, Friedrich-Barnewitz-Straße 4, 18119 Rostock, Germany., Bajer D; Institute for Biomedical Engineering, Rostock University Medical Center, Friedrich-Barnewitz-Straße 4, 18119 Rostock, Germany., Grabow N; Institute for Biomedical Engineering, Rostock University Medical Center, Friedrich-Barnewitz-Straße 4, 18119 Rostock, Germany.; Department Life, Light & Matter (LLM), University of Rostock, Albert-Einstein Str. 25, 18059 Rostock, Germany., Oschatz S; Institute for Biomedical Engineering, Rostock University Medical Center, Friedrich-Barnewitz-Straße 4, 18119 Rostock, Germany.

Publikováno v: ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2024 Sep 09; Vol. 10 (9), pp. 5844-5855. Date of Electronic Publication: 2024 Aug 23.