Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Baixing, Wu"'
Autor:
Wenting Guo, Xiaojia Li, Jingyu Fan, Hongwei Li, Yan Wen, Chunyan Meng, Haitao Chen, Zhipeng Zhao, Yuling Zhang, Yushen Du, Baixing Wu
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107672- (2023)
Summary: Non-natural nucleobase isocytosine (IC) is the isomer of cytosine; its chemical derivate 5-fluoroisocytosine (5-FIC) together with the isocytosine-specific deaminase (ICD) VCZ was suggested to be potential practical enzyme/prodrug pair for c
Externí odkaz:
https://doaj.org/article/84c16e68fb0147219d671ae3b36e2cbe
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Pseudouridine (Ψ) is one of the most abundant RNA modifications in cellular RNAs that post-transcriptionally impact many aspects of RNA. However, the metabolic fate of modified RNA nucleotides has long been a question. A pseudouridine kinase (PsuK)
Externí odkaz:
https://doaj.org/article/4fb3a89509d343c6b03b19031b94f756
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundPrevious study implicated that genes of matrix metalloproteinase (MMP) family play an important role in tumor invasion, neoangiogenesis, and metastasis. However, the diverse expression patterns and prognostic values of 24 MMPs in colorectal
Externí odkaz:
https://doaj.org/article/3c9ee136d163405588785399b68cbec5
Autor:
Qi Qiu, Hailiang Mei, Xian Deng, Kaixuan He, Baixing Wu, Qingqing Yao, Jixiang Zhang, Falong Lu, Jinbiao Ma, Xiaofeng Cao
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
REF6 is a H3K27me3 histone demethylase that targets regions of active chromatin in the Arabidopsis genome. Here Qiu et al. show that REF6 preferentially binds unmethylated DNA via its zinc-finger domains suggesting that DNA methylation might deter RE
Externí odkaz:
https://doaj.org/article/c9fddf88484c4306b766b9bf3ea12f9a
Autor:
Baixing Wu, Shichen Su, Deepak P. Patil, Hehua Liu, Jianhua Gan, Samie R. Jaffrey, Jinbiao Ma
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
RNA-binding protein hnRNP A2/B1 is suggested to promote miRNA processing as a m6A 'reader'. Here, the authors determine crystal structures of RRM domains of hnRNP A2/B1 in complex with various RNA substrates and determine that hnRNP A2/B1 may functio
Externí odkaz:
https://doaj.org/article/4a42d300b72c449a91ee0c967c3ae42c
Autor:
Hehua Liu, Xiang Yu, Yiqing Chen, Jing Zhang, Baixing Wu, Lina Zheng, Phensinee Haruehanroengra, Rui Wang, Suhua Li, Jinzhong Lin, Jixi Li, Jia Sheng, Zhen Huang, Jinbiao Ma, Jianhua Gan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
RNA-cleaving DNA enzymes are catalytic DNA that can cleave RNA in a sequence-specific manner. Here, the authors report three crystal structures of the 8–17 DNAzyme that include the pre-catalytic state of the RNA cleavage reaction, providing insight
Externí odkaz:
https://doaj.org/article/569952859de44152927b432d9f1d3c01
Autor:
Shichen Su, Shanshan Li, Ting Deng, Minsong Gao, Yue Yin, Baixing Wu, Chao Peng, Jianzhao Liu, Jinbiao Ma, Kaiming Zhang
Publikováno v:
Cell Research. 32:982-994
N6-methyladenosine (m6A) is the most abundant ribonucleotide modification among eukaryotic messenger RNAs. The m6A “writer” consists of the catalytic subunit m6A-METTL complex (MAC) and the regulatory subunit m6A-METTL-associated complex (MACOM),
Publikováno v:
Journal of Integrative Plant Biology. 64:2309-2313
The structural basis for histone recognition by the histone chaperone nuclear autoantigenic sperm protein (NASP) remains largely unclear. Here, we showed that Arabidopsis thaliana AtNASP is a monomer and displays robust nucleosome assembly activity i
Autor:
Yifeng Hou, Zhentian Nie, Xiaofeng Cao, Wang Yong, Baixing Wu, Sisi Li, Hongbo Nie, Gao Yangyang, Shuxuan Quan, Jing Sun
Publikováno v:
Molecular Plant. 14:688-699
N6-methyladenosine (m6A), a ubiquitous internal modification of eukaryotic mRNAs, plays a vital role in almost every aspect of mRNA metabolism. However, there is little evidence documenting the role of m6A in regulating alternative polyadenylation (A
Publikováno v:
Frontiers in microbiology. 13
Pseudouridine (Ψ) is one of the most abundant RNA modifications in cellular RNAs that post-transcriptionally impact many aspects of RNA. However, the metabolic fate of modified RNA nucleotides has long been a question. A pseudouridine kinase (PsuK)