Mechanisms of traditional Chinese medicines in the treatment of allergic rhinitis using a network biology approach

Autor: Li Du, Xiaotong Ye, Manman Li, Huihui Wang, Baixia Zhang, Rao Zheng, Yun Wang

Publikováno v: Journal of Traditional Chinese Medical Sciences, Vol 8, Iss 1, Pp 82-89 (2021)

Objective: To systematically explore the effect and mechanism of traditional Chinese herbs in the treatment of allergic rhinitis. Methods: Magnolia flower, xanthium fruit, astragalus root, paniculate cynanchum, scutellaria root, cicada molting, steph

Externí odkaz: https://doaj.org/article/8875b0a0834642f89d619fbeb5e87357

Study on the Antibreast Cancer Mechanism and Bioactive Components of Si-Wu-Tang by Cell Type-Specific Molecular Network

Autor: Yun Wang, Rao Zheng, Baixia Zhang

Publikováno v: Evidence-Based Complementary and Alternative Medicine, Vol 2020 (2020)

Si-Wu-Tang (SWT), a traditional Chinese herbal formula, has shown an effect on antibreast cancer. However, the mechanisms and bioactive components of SWT are still unclear. Fortunately, cell type-specific molecular network has provided an effective m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16a7d9a7d3c7c6e6708a9ae538d8853
https://doi.org/10.1155/2020/2345970

Tanshinone prevents alveolar bone loss in ovariectomized osteoporosis rats by up-regulating phosphoglycerate dehydrogenase

Autor: Nan Wang, Luyao Wang, Liangxing Cheng, Baixia Zhang, Feng Wang

Publikováno v: Toxicology and applied pharmacology. 376

Osteoporosis is manifested by reduced bone mass. Tanshinone has been shown to affect osteoclast differentiation, but its role in osteoporosis remains less clear. This study aimed to investigate the effects and molecular mechanisms of tanshinone on os

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efb376cefc0b6a6e01c902372f2793a
https://pubmed.ncbi.nlm.nih.gov/31108107

Construction of Metabolism Prediction Models for CYP450 3A4, 2D6, and 2C9 Based on Microsomal Metabolic Reaction System

Autor: Man-man Li, Ran-Feng Du, Xiao-tong Ye, Yun Wang, Baixia Zhang, Yanjiang Qiao, Shuai-bing He

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 17; Issue 10; Pages: 1686
International Journal of Molecular Sciences, Vol 17, Iss 10, p 1686 (2016)

During the past decades, there have been continuous attempts in the prediction of metabolism mediated by cytochrome P450s (CYP450s) 3A4, 2D6, and 2C9. However, it has indeed remained a huge challenge to accurately predict the metabolism of xenobiotic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d548f1affa612a913d9cef29fd8d554d
http://europepmc.org/articles/PMC5085718

A Network Pharmacology Approach to Uncover the Pharmacological Mechanism of XuanHuSuo Powder on Osteoarthritis

Autor: Yikun Sun, Yun Wang, Baixia Zhang, Shilin Luo, Xinyue Zhang, Zhi-Qian Zhang, Xiaojie Duan, Wenqi Wang, Shuaibing He, Huaqi Tang

Publikováno v: Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2016 (2016)

As the most familiar type of arthritis and a chronic illness of the joints, Osteoarthritis (OA) affects a great number of people on the global scale. XuanHuSuo powder (XHSP), a conventional herbal formula from China, has been extensively applied in O

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe6c9545284a2be65eaec04bd90399c