Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bairon Hernandez"'
Autor:
Jesse D. Cushman, Gonzalo Riadi, Janine H. Santos, Sheryl S. Moy, Patricia Jensen, Oswaldo A. Lozoya, Tianyuan Wang, Fuhua Xu, Richard P. Woychik, Dagoberto Grenet, Artiom Gruzdev, Thomas B Hagler, Korey D. Stevanovic, Bairon Hernandez
Publikováno v:
Life Science Alliance
This study shows that loss of a brain-specific fusion isoform of PGC1a leads to up-regulation of genes and motor impairments in mice, suggesting functional differences between PGC1 isoforms in the brain.
PGC1α is a transcriptional coactivator i
PGC1α is a transcriptional coactivator i
Autor:
Sheryl S. Moy, Fuhua Xu, Oswaldo A. Lozoya, Gonzalo Riadi, Janine H. Santos, Dagoberto Grenet, Korey D. Stevanovic, Patricia Jensen, Richard P. Woychik, Tianyuan Wang, Jesse D. Cushman, Bairon Hernandez
The peroxisome proliferator-activated receptor gamma co-activator 1 alpha (PGC1α) is known as a transcriptional co-activator in peripheral tissues but its function in the brain remains poorly understood. Various brain-specific Pgc1α isoforms have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f30b903ec1767ede0cb5aea25c2d0cd2
https://doi.org/10.1101/2020.09.18.300418
https://doi.org/10.1101/2020.09.18.300418
Autor:
Sheryl S. Moy, Bairon Hernandez, Korey D. Stevanovic, Dagoberto Grenet, Oswaldo A. Lozoya, Jesse D. Cushman, Artiom Gruzdev, Thomas B Hagler, Fuhua Xu, Patricia Jensen, Richard P. Woychik, Gonzalo Riadi, Janine H. Santos, Tianyuan Wang
Publikováno v:
Life Science Alliance. 4:e202101122
PGC1α is a transcriptional coactivator in peripheral tissues, but its function in the brain remains poorly understood. Various brain-specific Pgc1α isoforms have been reported in mice and humans, including two fusion transcripts (FTs) with non-codi
Autor:
Gonzalo Riadi, Bairon Hernandez
Publikováno v:
Proceedings of MOL2NET 2018, International Conference on Multidisciplinary Sciences, 4th edition.
A Fusion Transcript (FT) is a RNA molecule product of cis/trans-splicing of two differently annotated elements, either genes or Transposable Elements (TE). It may be coding or non-coding. There are many examples of gene-gene FTs in cancer. Lately, FT