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Akademický článek

Vorinostat Improves Myotonic Dystrophy Type 1 Splicing Abnormalities in DM1 Muscle Cell Lines and Skeletal Muscle from a DM1 Mouse Model.

Autor: Neault N; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 5B2, Canada.; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Eric Poulin Center for Neuromuscular Disease, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Ravel-Chapuis A; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Eric Poulin Center for Neuromuscular Disease, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; School of Pharmaceutical Sciences, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Baird SD; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 5B2, Canada., Lunde JA; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Eric Poulin Center for Neuromuscular Disease, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Poirier M; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 5B2, Canada., Staykov E; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 5B2, Canada., Plaza-Diaz J; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 5B2, Canada.; Department of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, 18071 Granada, Spain.; Instituto de Investigación Biosanitaria IBS.GRANADA, Complejo Hospitalario Universitario de Granada, 18014 Granada, Spain., Medina G; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 5B2, Canada., Abadía-Molina F; Institute of Nutrition and Food Technology 'José Mataix', Biomedical Research Center, University of Granada, Armilla, 18016 Granada, Spain.; Department of Cell Biology, School of Sciences, University of Granada, 18071 Granada, Spain., Jasmin BJ; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Eric Poulin Center for Neuromuscular Disease, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada., MacKenzie AE; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 5B2, Canada.; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Eric Poulin Center for Neuromuscular Disease, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 14; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 14.

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Akademický článek

Outcome with surgical treatment of canine soft tissue sarcoma in the region of the ischiatic tuberosity: A veterinary society of surgical oncology retrospective study.

Autor: Paulos PE; VCA Canada, Mississauga-Oakville Veterinary Emergency Hospital, Oakville, Ontario, Canada., Boston S; VCA Canada, Mississauga-Oakville Veterinary Emergency Hospital, Oakville, Ontario, Canada., Skinner OT; Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, Missouri, USA., Liptak JM; VCA Canada, Alta Vista Animal Hospital, Ottawa, Ontario, Canada., Amsellem PM; Department of Veterinary Clinical Sciences, University of Minnesota, Minneapolis, Minnesota, USA., Fournier Q; Fitzpatrick Referrals Oncology and Soft Tissue, Surrey, UK., Wood CJ; Clinical Sciences Department, Colorado State University, Fort Collins, Colorado, USA., Annoni M; AniCura Clinica Veterinaria, Milan, Italy., Murgia D; Dick White Referrals, Cambridgeshire, UK., Oblak ML; Department of Clinical Studies, Ontario Veterinary College, Guelph, Ontario, Canada., Dean BL; Southern Counties Veterinary Specialists, Hampshire, UK., Baird SD; Earlswood Veterinary Referrals, Belfast, UK., Kulendra NJ; North Downs Specialist Referrals, Surrey, UK.

Publikováno v: Veterinary and comparative oncology [Vet Comp Oncol] 2022 Sep; Vol. 20 (3), pp. 669-678. Date of Electronic Publication: 2022 Apr 25.

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Akademický článek

High-throughput kinome-RNAi screen identifies protein kinase R activator (PACT) as a novel genetic modifier of CUG foci integrity in myotonic dystrophy type 1 (DM1).

Autor: Neault N; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada., O'Reilly S; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada., Baig AT; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada., Plaza-Diaz J; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada., Azimi M; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada., Farooq F; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada., Baird SD; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada., MacKenzie A; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.

Publikováno v: PloS one [PLoS One] 2021 Sep 14; Vol. 16 (9), pp. e0256276. Date of Electronic Publication: 2021 Sep 14 (Print Publication: 2021).

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Akademický článek

Identification of pannexin 1-regulated genes, interactome, and pathways in rhabdomyosarcoma and its tumor inhibitory interaction with AHNAK.

Autor: Xiang X; Molecular Biomedicine Program, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada., Langlois S; Molecular Biomedicine Program, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.; Department of Surgery, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada., St-Pierre ME; Molecular Biomedicine Program, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada., Blinder A; Molecular Biomedicine Program, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada., Charron P; Molecular Biomedicine Program, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada., Graber TE; Molecular Biomedicine Program, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada., Fowler SL; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada.; Neural Regeneration Laboratory and Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada.; UK Dementia Research Institute, University College London, London, UK., Baird SD; Molecular Biomedicine Program, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada., Bennett SAL; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada.; Neural Regeneration Laboratory and Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada., Alain T; Molecular Biomedicine Program, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada., Cowan KN; Molecular Biomedicine Program, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada. kcowan@cheo.on.ca.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada. kcowan@cheo.on.ca.; Department of Surgery, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada. kcowan@cheo.on.ca.

Publikováno v: Oncogene [Oncogene] 2021 Mar; Vol. 40 (10), pp. 1868-1883. Date of Electronic Publication: 2021 Feb 09.

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