Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Bainian Feng"'
Publikováno v:
PeerJ, Vol 9, p e12209 (2021)
The snail Oncomelania hupensis is the only intermediate host of the highly invasive parasite Schistosoma japonicum. Molluscicide is often used to curb transmission of S. japonicum. Niclosamide, the only World Health Organization (WHO) recognized moll
Externí odkaz:
https://doaj.org/article/83216b4b13a54242b65437cd2457ca57
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2031 (2022)
Chicoric acid (CA), a polyphenolic acid compound extracted from chicory and echinacea, possesses antiviral, antioxidative and anti-inflammatory activities. Growing evidence supports the pivotal roles of brain–spleen and brain–gut axes in neurodeg
Externí odkaz:
https://doaj.org/article/429329eb4f4548058467baf0b4fc6367
Autor:
Wen-Long Wang, Dong-Lin Yang, Li-Xin Gao, Chun-Lan Tang, Wei-Ping Ma, Hui-Hua Ye, Si-Qi Zhang, Ya-Nan Zhao, Hao-Jie Xu, Zhao Hu, Xia Chen, Wen-Hua Fan, Hai-Jun Chen, Jing-Ya Li, Fa-Jun Nan, Jia Li, Bainian Feng
Publikováno v:
Molecules, Vol 19, Iss 1, Pp 102-121 (2013)
A series of 1H-2,3-dihydroperimidine derivatives was designed, synthesized, and evaluated as a new class of inhibitors of protein tyrosine phosphatase 1B (PTP1B) with IC50 values in the micromolar range. Compounds 46 and 49 showed submicromolar inhib
Externí odkaz:
https://doaj.org/article/618717cae9844bf79ad9a10f3f4822f4
Autor:
Chuan-Xin Yu, Bainian Feng, Wen-Hua Fan, Gu-Ping Wang, Xu-Ren Yin, Xia Chen, Li-Jun Song, Wen-Long Wang
Publikováno v:
Molecules, Vol 18, Iss 8, Pp 9163-9178 (2013)
The synthesis and structure-activity relationship (SAR) studies of praziquantel derivatives with activity against adult Schistosoma japonicum are described. Several of them showed better worm killing activity than praziquantel and could serve as lead
Externí odkaz:
https://doaj.org/article/d0b3efdc83254be7b21cf10a3dadfe84
Autor:
Wen-Long Wang, Hai-Jun Chen, Wei-Ping Ma, Min Gu, Min-Zhi Fan, Jing-Ya Li, Bainian Feng, Fa-Jun Nan
Publikováno v:
Molecules, Vol 17, Iss 12, Pp 14522-14530 (2012)
In order to study the effect of heterocyclic core conformational state of leucamide A on its anti-influenza virus A activity, five conformational analogues were prepared by replacing the Pro-Leu dipeptide in the molecule with various amino acids. The
Externí odkaz:
https://doaj.org/article/2abd9cbb86384fa78bec7322c8109fcb
Publikováno v:
Journal of Chemical & Engineering Data. 67:825-835
Publikováno v:
Pharmaceutical Chemistry Journal. 55:1028-1032
Publikováno v:
Letters in Drug Design & Discovery. 17:104-113
Background: This paper reviews the research progress of pyrazoloquinazolines which widely used in the field of medicine and pesticide in recent years. Five types of pyrazoloquinazolines are introduced: pyrazolo [4,3-h]quinazolines, pyrazolo[1,5-c]qui
Publikováno v:
Bioconjugate Chemistry. 31:174-181
γ-Glutamyltranspeptidase (GGT) is a cell -membrane-associated enzyme which has been recognized as a promising biomarker for the diagnosis of many malignant tumors. Herein, we rationally designed a fluorine-18 labeled small-molecule probe, [18F]γ-Gl
Publikováno v:
PeerJ
PeerJ, Vol 9, p e12209 (2021)
PeerJ, Vol 9, p e12209 (2021)
The snail Oncomelania hupensis is the only intermediate host of the highly invasive parasite Schistosoma japonicum. Molluscicide is often used to curb transmission of S. japonicum. Niclosamide, the only World Health Organization (WHO) recognized moll