Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Epithelial calcineurin controls microbiota-dependent intestinal tumor development

Autor: John F. Baines, Sven Künzel, Triantafyllos Chavakis, Clemens Schafmayer, Esther Bosse, Giuseppina Luzzi, Jan Hendrik Egberts, Alexander Arlt, Andrea Ulbricht, Gijs R. van den Brink, Anne Strigli, Sebastian Zeissig, Jochen Hampe, Richard S. Blumberg, Thomas Becker, Kenneth Peuker, Arthur Kaser, Yvonne Zeissig, Stefan Schreiber, Marco Bianchi, Jun Wang, Stefanie Muff, Marijana Basic, André Bleich, Christoph Röcken

Publikováno v: Nature Medicine
Nature medicine, 22(5), 506-515. Nature Publishing Group

Inflammation-associated pathways are active in intestinal epithelial cells (IECs) and contribute to the pathogenesis of colorectal cancer (CRC). Calcineurin, a phosphatase required for the activation of the nuclear factor of activated T cells (NFAT)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73fa9b1a22fade65d6955e2a4333e3c9
https://doi.org/10.1038/nm.4072

Advancing evolutionary medicine in Northern Germany: Collaboration between Kiel University's Medical Faculty and the Max Planck Institute for Evolutionary Biology.

Autor: Baines JF; Section of Evolutionary Medicine, Institute of Experimental Medicine, Kiel University, Kiel, Germany.; Guest Group Evolutionary Medicine, Max Planck Institute for Evolutionary Biology, Plön, Germany., Baldus CD; Medical Department II, Hematology and Oncology, University Hospital Schleswig-Holstein, Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany., Bertels F; Department of Microbial Population Biology, Max Planck Institute for Evolutionary Biology, Plön, Germany., Brüggemann M; Medical Department II, Hematology and Oncology, University Hospital Schleswig-Holstein, Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany., Kaleta C; Research Group Medical Systems Biology, Institute of Experimental Medicine, Kiel University, Kiel, Germany., Laudes M; Institute of Diabetes and Clinical Metabolic Research, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany., Mueller FJ; Department of Psychiatry and Psychotherapy, Kiel University and University Hospital Schleswig-Holstein, Kiel, Germany.; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany., Odenthal-Hesse L; Research Group Meiotic Recombination and Genome Instability, Max Planck Institute for Evolutionary Biology, Plön, Germany., Poyet M; Section of Evolutionary Medicine, Institute of Experimental Medicine, Kiel University, Kiel, Germany., Rainey PB; Department of Microbial Population Biology, Max Planck Institute for Evolutionary Biology, Plön, Germany.; Laboratory of Biophysics and Evolution, ESPCI, Université Paris Sciences et Lettres, Paris, France., Rosenstiel P; Institute of Clinical Molecular Biology, Kiel University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany., Scheffold A; Institute of Immunology, Kiel University and University Medical Center Schleswig-Holstein, Kiel, Germany., Sebens S; Institute for Experimental Cancer Research, Kiel University, University Hospital Schleswig-Holstein (UKSH), Kiel, Germany., Thiery J; Faculty of Medicine, Kiel University and University Hospital Schleswig-Holstein (UKSH), Kiel, Germany., Traulsen A; Department of Theoretical Biology, Max Planck Institute for Evolutionary Biology, Plön, Germany.

Publikováno v: Evolution, medicine, and public health [Evol Med Public Health] 2024 Jul 24; Vol. 12 (1), pp. 117-121. Date of Electronic Publication: 2024 Jul 24 (Print Publication: 2024).

Cytokine and Microbiome Changes in Adolescents with Anorexia Nervosa at Admission, Discharge, and One-Year Follow-Up.

Autor: Käver L; Institute of Neuroanatomy, RWTH Aachen University, Wendlingweg 2, 52074 Aachen, Germany.; West German Center for Child and Adolescent Health (WZKJ), University Hospital Cologne, Kerpener Str. 62, 50931 Cologne, Germany., Voelz C; Institute of Neuroanatomy, RWTH Aachen University, Wendlingweg 2, 52074 Aachen, Germany.; West German Center for Child and Adolescent Health (WZKJ), University Hospital Cologne, Kerpener Str. 62, 50931 Cologne, Germany., Specht HE; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital RWTH Aachen, Neuenhofer Weg 21, 52074 Aachen, Germany., Thelen AC; Institute of Neuroanatomy, RWTH Aachen University, Wendlingweg 2, 52074 Aachen, Germany., Keller L; West German Center for Child and Adolescent Health (WZKJ), University Hospital Cologne, Kerpener Str. 62, 50931 Cologne, Germany.; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital RWTH Aachen, Neuenhofer Weg 21, 52074 Aachen, Germany.; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LVR University Hospital Essen, Virchowstrasse 174, 45147 Essen, Germany., Dahmen B; West German Center for Child and Adolescent Health (WZKJ), University Hospital Cologne, Kerpener Str. 62, 50931 Cologne, Germany.; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital RWTH Aachen, Neuenhofer Weg 21, 52074 Aachen, Germany., Andreani NA; Max Planck Institute for Evolutionary Biology, August-Thienemann-Str. 2, 24306 Plön, Germany.; Institute for Experimental Medicine, Kiel University, Christian-Albrechts-Platz 4, 24118 Kiel, Germany., Tenbrock K; West German Center for Child and Adolescent Health (WZKJ), University Hospital Cologne, Kerpener Str. 62, 50931 Cologne, Germany.; Department of Pediatrics, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany.; Department of Pediatrics, Pediatric Rheumatology, Inselspital University of Bern, Freiburgstrasse 15, 3010 Bern, Switzerland., Biemann R; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Paul-List-Straße 13/15, 04103 Leipzig, Germany., Borucki K; Institute for Clinical Chemistry and Pathobiochemistry, Otto-von-Guericke University Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany., Dempfle A; Institute of Medical Informatics and Statistics, Kiel University, Brunswicker Str. 10, 24105 Kiel, Germany., Baines JF; Max Planck Institute for Evolutionary Biology, August-Thienemann-Str. 2, 24306 Plön, Germany.; Institute for Experimental Medicine, Kiel University, Christian-Albrechts-Platz 4, 24118 Kiel, Germany., Beyer C; Institute of Neuroanatomy, RWTH Aachen University, Wendlingweg 2, 52074 Aachen, Germany., Herpertz-Dahlmann B; West German Center for Child and Adolescent Health (WZKJ), University Hospital Cologne, Kerpener Str. 62, 50931 Cologne, Germany.; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital RWTH Aachen, Neuenhofer Weg 21, 52074 Aachen, Germany., Trinh S; Institute of Neuroanatomy, RWTH Aachen University, Wendlingweg 2, 52074 Aachen, Germany.; West German Center for Child and Adolescent Health (WZKJ), University Hospital Cologne, Kerpener Str. 62, 50931 Cologne, Germany., Seitz J; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LVR University Hospital Essen, Virchowstrasse 174, 45147 Essen, Germany.; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital RWTH Aachen, Neuenhofer Weg 21, 52074 Aachen, Germany.; West German Center for Child and Adolescent Health (WZKJ), University Hospital Cologne, Kerpener Str. 62, 50931 Cologne, Germany.

Publikováno v: Nutrients [Nutrients] 2024 May 23; Vol. 16 (11). Date of Electronic Publication: 2024 May 23.