A Sputum 6 Gene Expression Signature Predicts Inflammatory Phenotypes and Future Exacerbations of COPD

Autor: Baines KJ, Negewo NA, Gibson PG, Fu JJ, Simpson JL, Wark PAB, Fricker M, McDonald VM

Publikováno v: International Journal of COPD, Vol Volume 15, Pp 1577-1590 (2020)

Katherine J Baines,1 Netsanet A Negewo,1 Peter G Gibson,1,2 Juan-Juan Fu,3 Jodie L Simpson,1 Peter AB Wark,1,2 Michael Fricker,1 Vanessa M McDonald1,2,4 1Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, The University of

Externí odkaz: https://doaj.org/article/47008296d16b4df18c292069e9a26f31

Airway gene expression of IL-1 pathway mediators predicts exacerbation risk in obstructive airway disease

Autor: Baines KJ, Fu JJ, McDonald VM, Gibson PG

Publikováno v: International Journal of COPD, Vol Volume 12, Pp 541-550 (2017)

Katherine J Baines,1,2 Juan-juan Fu,3 Vanessa M McDonald,1,2 Peter G Gibson1,2 1Faculty of Health and Medicine, Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, The University of Newcastle, 2Department of Respiratory and

Externí odkaz: https://doaj.org/article/8ef277a669424c2abd22b5f1f9b0761c

Saturated fatty acids, obesity, and the nucleotide oligomerization domain–like receptor protein 3 (NLRP3) inflammasome in asthmatic patients

Autor: Wood, LG, Li, Q, Scott, HA, Rutting, S, Berthon, BS, Gibson, PG, Hansbro, PM, Williams, E, Horvat, J, Simpson, JL, Young, P, Oliver, BG, Baines, KJ

© 2018 American Academy of Allergy, Asthma & Immunology Background: Both obesity and high dietary fat intake activate the nucleotide oligomerization domain–like receptor protein 3 (NLRP3) inflammasome. Objective: We aimed to examine NLRP3 inflamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::afb6602d51b4698366a3f383bc67523a
https://hdl.handle.net/10453/131675

MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD

Autor: Hsu, ACY, Dua, K, Starkey, MR, Haw, TJ, Nair, PM, Nichol, K, Zammit, N, Grey, ST, Baines, KJ, Foster, PS, Hansbro, PM, Wark, PA

Influenza A virus (IAV) infections lead to severe inflammation in the airways. Patients with chronic obstructive pulmonary disease (COPD) characteristically have exaggerated airway inflammation and are more susceptible to infections with severe sympt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::91de6c33cc1fe2a83045e9ba5cf0f479
https://hdl.handle.net/10453/126214

Autism likelihood in infants born to mothers with asthma is associated with blood inflammatory gene biomarkers in pregnancy.

Autor: Murphy VE; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW, 2308, Australia., Whalen OM; School of Psychological Sciences, College of Engineering, Science and Environment, The University of Newcastle, Callaghan, NSW, 2308, Australia., Williams EJ; School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW, 2308, Australia., Gibson PG; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW, 2308, Australia.; Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, NSW, 2305, Australia., Campbell LE; School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW, 2308, Australia., Karayanidis F; School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW, 2308, Australia., Mallise CA; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW, 2308, Australia.; Population Health, Hunter New England Local Health District, Wallsend, NSW, 2287, Australia., Woolard A; Telethon Kids Institute, Perth Children's Hospital, Perth, WA, 6009, Australia., Robijn AL; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW, 2308, Australia., Mattes J; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW, 2308, Australia.; Paediatric Respiratory and Sleep Medicine Department, John Hunter Children's Hospital, Newcastle, NSW, 2305, Australia., Collison AM; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW, 2308, Australia., Lane AE; Olga Tennison Autism Research Centre, La Trobe University, Melbourne, VIC, 3086, Australia., Baines KJ; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW, 2308, Australia.; School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW, 2308, Australia.

Publikováno v: Brain, behavior, & immunity - health [Brain Behav Immun Health] 2024 Aug 13; Vol. 40, pp. 100845. Date of Electronic Publication: 2024 Aug 13 (Print Publication: 2024).