The Regulation of Metabolic Homeostasis by Incretins and the Metabolic Hormones Produced by Pancreatic Islets

Autor: Reed J, Bain SC, Kanamarlapudi V

Publikováno v: Diabetes, Metabolic Syndrome and Obesity, Vol Volume 17, Pp 2419-2456 (2024)

Joshua Reed, Stephen C Bain, Venkateswarlu Kanamarlapudi Institute of Life Science, Medical School, Swansea University, Swansea, SA2 8PP, UKCorrespondence: Venkateswarlu Kanamarlapudi, Institute of Life Science, Medical School, Swansea University, Sw

Externí odkaz: https://doaj.org/article/46b961f9e98b4bb0ab5a50e1c0e4136f

A review of sitagliptin with special emphasis on its use in moderate to severe renal impairment

Autor: Eligar VS, Bain SC

Publikováno v: Drug Design, Development and Therapy, Vol 2013, Iss default, Pp 893-903 (2013)

Vinay S Eligar,1 Stephen C Bain2 1University Hospital of Wales, Cardiff, UK; 2Singleton Hospital, Swansea University, Swansea, UK Abstract: Sitagliptin is the first dipeptidylpeptidase-4 inhibitor to be used in the management of type 2 diabetes. It i

Externí odkaz: https://doaj.org/article/400d307716b74effb7a036daec65aae4

Effects of liraglutide on cardiovascular outcomes in patients with type 2 diabetes mellitus with or without history of myocardial infarction or stroke

Autor: Verma, S, Poulter, NR, Bhatt, DL, Bain, SC, Buse, JB, Leiter, LA, Nauck, MA, Pratley, RE, Zinman, B, Ørsted, DD, Monk Fries, T, Rasmussen, S, Marso, SP

BACKGROUND: The glucagon-like peptide-1 analog liraglutide reduced cardiovascular events and mortality in patients with type 2 diabetes mellitus in the LEADER trial (Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes). In a post hoc analysis,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::764ce016788f74baa45c3769fb06c58f
http://hdl.handle.net/10044/1/90481

COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study

Autor: Hall, Victoria Jane, Foulkes, Sarah, Saei, Ayoub, Andrews, Nick, Oguti, Blanche, Charlett, Andre, Wellington, Edgar, Stowe, Julia, Gillson, Natalie, Atti, Ana, Islam, Jasmin, Karagiannis, Ioannis, Munro, Katie, Khawam, Jameel, Chand, Meera A, Brown, Colin S, Ramsay, Mary, Lopez-Bernal, Jamie, Hopkins, Susan, Andrews, N, Atti, A, Aziz, H, Brooks, T, Brown, CS, Camero, D, Carr, C, Chand, MA, Charlett, A, Crawford, H, Cole, M, Conneely, J, D'Arcangelo, S, Ellis, J, Evans, S, Foulkes, S, Gillson, N, Gopal, R, Hall, L, Hall, VJ, Harrington, P, Hopkins, S, Hewson, J, Hoschler, K, Ironmonger, D, Islam, J, Kall, M, Karagiannis, I, Kay, O, Khawam, J, King, E, Kirwan, P, Kyffin, R, Lackenby, A, Lattimore, M, Linley, E, Lopez-Bernal, J, Mabey, L, McGregor, R, Miah, S, Monk, EJM, Munro, K, Naheed, Z, Nissr, A, O'Connell, AM, Oguti, B, Okafor, H, Organ, S, Osbourne, J, Otter, A, Patel, M, Platt, S, Pople, D, Potts, K, Ramsay, M, Robotham, J, Rokadiya, S, Rowe, C, Saei, A, Sebbage, G, Semper, A, Shrotri, M, Simmons, R, Soriano, A, Staves, P, Taylor, S, Taylor, A, Tengbe, A, Tonge, S, Vusirikala, A, Wallace, S, Wellington, E, Zambon, M, Corrigan, D, Sartaj, M, Cromey, L, Campbell, S, Braithwaite, K, Price, L, Haahr, L, Stewart, S, Lacey, ED, Partridge, L, Stevens, G, Ellis, Y, Hodgson, H, Norman, C, Lacey, ED, Larru, B, Mcwilliam, S, Roynon, A, Northfield, J, Winchester, S, Cieciwa, P, Pai, A, Bakker, P, Loughrey, C, Watt, A, Adair, F, Hawkins, A, Grant, A, Temple-Purcell, R, Howard, J, Slawson, N, Subudhi, C, Davies, S, Bexley, A, Penn, R, Wong, N, Boyd, G, Rajgopal, A, Arenas-Pinto, A, Matthews, R, Whileman, A, Laugharne, R, Ledger, J, Barnes, T, Jones, C, Osuji, N, Chitalia, N, Bailey, T, Akhtar, S, Harrison, G, Horne, S, Walker, N, Agwuh, K, Maxwell, V, Graves, J, Williams, S, O'Kelly, A, Ridley, P, Cowley, A, Johnstone, H, Swift, P, Democratis, J, Meda, M, Brake, S, Gunn, J, Selassi, A, Hams, S, Irvine, V, Chandrasekaran, B, Forsyth, C, Radmore, J, Thomas, C, Brown, K, Roberts, S, Burns, P, Gajee, K, Lewis, T, Byrne, TM, Sanderson, F, Knight, S, Macnaughton, E, Burton, BJL, Smith, H, Chaudhuri, R, Aeron-Thomas, J, Hollinshead, K, Shorten, RJ, Swan, A, Shorten, RJ, Favager, C, Murira, J, Baillon, S, Hamer, S, Shah, A, Russell, J, Brennan, D, Dave, A, Chawla, A, Westwell, F, Adeboyeku, D, Papineni, P, Pegg, C, Williams, M, Ahmad, S, Horsley, A, Gabriel, C, Pagget, K, Cieciwa, P, Maloney, G, Ashcroft, J, Del Rosario, I, Crosby-Nwaobi, R, Flanagan, D, Dhasmana, D, Fowler, S, Cameron, E, Prentice, L, Sinclair, C, Irvine, V, Bateman, V, McLelland-Brooks, K, Ho, A, Murphy, M, Cochrane, A, Gibson, A, Patel, M, Black, K, Tempeton, K, Donaldson, S, Coke, L, Elumogo, N, Elliott, J, Padgett, D, Cross, A, Mirfenderesky, M, Joyce, S, Sinanovic, I, Howard, M, Lewis, T, Cowling, P, Brazil, M, Hanna, E, Abdelrazik, A, Brand, S, Sheridan, EA, Wadams, B, Lloyd, A, Mouland, J, Giles, J, Pottinger, G, Coles, H, Joseph, M, Lee, M, Orr, S, Chenoweth, H, Browne, D, Auckland, C, Lear, R, Mahungu, T, Rodger, A, Warren, S, Brooking, D, Pai, S, Druyeh, R, Smith, E, Stone, S, Meisner, S, Delgado, D, Underhill, E, Keen, L, Aga, M, Domingos, P, Gormley, S, Kerrison, C, Birch, S, DeSilva, T, Allsop, L, Ambalkar, S, Beekes, M, Jose, S, Tomlinson, J, Painter, Sharen, Price, C, Pepperell, J, James, K, Trinick, T, Moore, L, Day, J, Boulos, A, Knox, I, Defever, E, McCracken, D, Brown, K, Gray, K, Houston, A, Planche, T, Pritchard Jones, R, Wycherley, Diane, Bennett, S, Marrs, J, Nimako, K, Stewart, B, Bain, SC, Kalakonda, N, Khanduri, S, Ashby, A, Holden, M, Mahabir, N, Harwood, J, Payne, B, Court, K, White, N, Longfellow, R, Hughes, LE, Green, ME, Halkes, M, Mercer, P, Roebuck, A, Wilson-Davies, E, Gallego, L, Lazarus, R, Aldridge, N, Berry, L, Game, F, Reynolds, T, Holmes, C, Wiselka, M, Higham, A, Booth, M, Duff, C, Alderton, J, Hilton, D, Powell, J, Jackson, A, Plant, AJ, Ahmed, N, Chin, T, Qazzafi, MZ, Moody, AM, Tilley, RE, Donaghy, T, O'Kane, M, Shipman, K, Sierra, R, Parmar, C, Mills, G, Harvey, D, Huang, YWJ, Birch, J, Robinson, L, Board, S, Broadley, A, Laven, C, Todd, N, Eyre, DW, Jeffery, K, Dunachie, S, Duncan, C, Klenerman, P, Turtle, L, Baxendale, H, Heeney, JL

Publikováno v: The Lancet; May 2021, Vol. 397 Issue: 10286 p1725-1735, 11p

LEADER-4: blood pressure control in patients with type 2 diabetes and high cardiovascular risk: baseline data from the LEADER randomized trial

Autor: Petrie, JR, Marso, SP, Bain, SC, Franek, E, Jacob, S, Masmiquel, L, Leiter, LA, Haluzik, M, Satman, I, Omar, M, Shestakova, M, Van Gaal, L, Mann, JF, Baeres, FM, Zinman, B, Poulter, NR, LEADER investigators

Publikováno v: Journal of hypertension
Journal of Hypertension

Objective: As glucagon-like peptide-1 receptor agonists lower blood pressure (BP) in type 2 diabetes mellitus (T2DM), we examined BP control in relation to targets set by international bodies prior to randomization in the Liraglutide Effect and Actio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bde80e35bc7f47df055c0d2b64ac39
https://eprints.gla.ac.uk/116246/1/116246.pdf