Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bailee Kain"'
Autor:
Duy T. Le, Marcus A. Florez, Pawel Kus, Brandon T. Tran, Bailee Kain, Yingmin Zhu, Kurt Christensen, Antrix Jain, Anna Malovannaya, Katherine Y. King
Publikováno v:
iScience, Vol 26, Iss 2, Pp 106059- (2023)
Summary: Basic leucine zipper ATF-like transcription factor 2 (BATF2), an interferon-activated immune response regulator, is a key factor responsible for myeloid differentiation and depletion of HSC during chronic infection. To delineate the mechanis
Externí odkaz:
https://doaj.org/article/e0f2acdc911f4e5bae8d8d550d626801
Autor:
Daniel E Morales-Mantilla, Bailee Kain, Duy Le, Anthony R Flores, Silke Paust, Katherine Y King
Publikováno v:
eLife, Vol 11 (2022)
New therapeutic strategies to reduce sepsis-related mortality are urgently needed, as sepsis accounts for one in five deaths worldwide. Since hematopoietic stem and progenitor cells (HSPCs) are responsible for producing blood and immune cells, includ
Externí odkaz:
https://doaj.org/article/1ecc94ceb31643ec856806ce8828d58f
Autor:
Bailee Kain, Pamela N. Luna, Daniel E. Morales-Mantilla, Duy T. Le, Brandon Tran, Marcus Florez, Laure Maneix, Jack Toups, Hyojeong Han, Roman Jaksik, Yun Huang, Andre Catic, Chad A. Shaw, Katherine Y. King
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8669cd71bbc7862d23843dc1081d659e
https://doi.org/10.2139/ssrn.4048388
https://doi.org/10.2139/ssrn.4048388
Autor:
Duy T. Le, Daniel E. Morales-Mantilla, Bailee Kain, Katherine Y. King, Anthony R Flores, Silke Paust
Publikováno v:
eLife, Vol 11 (2022)
Sepsis is a dysregulated inflammatory syndrome that accounts for as many as 20% of deaths worldwide. Elevated production of pro-inflammatory cytokines during sepsis, such as IL-1, IL-6, interferons (IFNs), and tumor necrosis factor contribute to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24534375a905ccdf8b904de443cba2e7
https://pubmed.ncbi.nlm.nih.gov/35166205
https://pubmed.ncbi.nlm.nih.gov/35166205
Autor:
Pawel Kus, Bailee Kain, Roman Jaksik, Xiaochen Long, Daniel Hormaechea-Agulla, Katherine Y. King, Duy T. Le, Katie A. Matatall, Marek Kimmel, Grant A. Challen
Publikováno v:
Cell stem cell. 28(8)
Age-related clonal hematopoiesis (CH) is a risk factor for malignancy, cardiovascular disease, and all-cause mortality. Somatic mutations in DNMT3A are drivers of CH, but decades may elapse between the acquisition of a mutation and CH, suggesting tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d74a9ac9ec06335c187ae944f3273d
https://pubmed.ncbi.nlm.nih.gov/34358435
https://pubmed.ncbi.nlm.nih.gov/34358435
Autor:
Roman Jaksik, Bailee Kain, Duy T. Le, Katie A. Matatall, Daniel Hormaechea Agulla, Xiaochen Long, Pawel Kus, Katherine Y. King, Marek Kimmel, Grant A. Challen
Publikováno v:
SSRN Electronic Journal.
Age-related clonal hematopoiesis (CH) is a risk factor for malignancy, cardiovascular disease and all-cause mortality. Somatic mutations in DNMT3A are drivers of CH, but decades may elapse between acquisition of a mutation and CH, suggesting that env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::778baff8bd963e82d7a79fbdcd9b9c7d
https://doi.org/10.2139/ssrn.3564993
https://doi.org/10.2139/ssrn.3564993
Autor:
Bailee Kain, Katherine Y. King, Laure Maneix, Duy T. Le, Pam Luna, Marcus A Florez, Hyojeong Han, Jack Toups, Roman Jaksik, Daniel Hormaechea Agulla, Andre Catic, Brandon Tran, Daniel E. Morales-Mantilla, Chad A. Shaw
Publikováno v:
Blood. 138:2149-2149
When innate immune cells and hematopoietic stem and progenitor cells (HSPCs) are exposed to pathogenic agents, they develop heightened responses to subsequent infection through a process called trained immunity. After exposure to a pathogen, bone mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e60041854c03ac00c819c4a6167829b9
https://doi.org/10.1182/blood-2021-151189
https://doi.org/10.1182/blood-2021-151189
Autor:
Javier Cabrea-Perez, Youngjae Jeong, Katherine Y. King, Dongsu Park, Bailee Kain, Marcus A Florez, Duy T. Le
Publikováno v:
Blood. 138:1098-1098
Chronic infections are prevalent worldwide and contribute to bone marrow failure syndromes. Long-term homeostatic production of all blood cells is dependent on the ability of hematopoietic stem cells (HSCs) to remain mostly quiescent and, upon activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bee5a216238346cf048a21d587a05f6
https://doi.org/10.1182/blood-2021-151567
https://doi.org/10.1182/blood-2021-151567
Autor:
Katherine Y. King, Bailee Kain, Matthew T Burchill, Taylor S. Mills, Beth A. Jirón Tamburini, Erin D. Lucas, Eric M. Pietras
Publikováno v:
Blood. 138:2165-2165
Auto-immune diseases (AD) are characterized by repeated flares of disease activity separated by periods of remission. Cycles of AD remission and relapse can occur even with therapeutic intervention and contribute to AD morbidity. Paradoxically, durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e09500c4260c9a8975d7024d1851eb8
https://doi.org/10.1182/blood-2021-151637
https://doi.org/10.1182/blood-2021-151637