Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Baihui Cao"'
Autor:
Baihui Cao, Xiaotong Chen, Yubin Li, Tian Zhou, Nuo Chen, Yaxin Guo, Ming Zhao, Chun Guo, Yongyu Shi, Qun Wang, Xuexiang Du, Lining Zhang, Yan Li
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract TFE3 and TFEB, as the master regulators of lysosome biogenesis and autophagy, are well characterized to enhance the synaptic protein α-synuclein degradation in protecting against Parkinson’s disease (PD) and their levels are significantly
Externí odkaz:
https://doaj.org/article/d34e10598fa84854b4b290b010860c15
Autor:
Nuo Chen, Xiaoyu Wang, Yaxin Guo, Ming Zhao, Baihui Cao, Bing Zhan, Yubin Li, Tian Zhou, Faliang Zhu, Chun Guo, Yongyu Shi, Qun Wang, Lining Zhang, Yan Li
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Tuberous sclerosis complex 2 (TSC2) crucially suppresses Rheb activity to prevent mTORC1 activation. However, mutations in TSC genes lead to mTORC1 overactivation, thereby causing various developmental disorders and cancer. Therefore, the di
Externí odkaz:
https://doaj.org/article/642c79be80334573bdcf7898b8170d4e
Autor:
Nuo Chen, Ming Zhao, Yaxin Guo, Nan Wu, Baihui Cao, Bing Zhan, Tian Zhou, Yubin Li, Faliang Zhu, WanJun Chen, Yan Li, Lining Zhang
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The potentiation of synaptic plasticity and serotonin generation by brain-derived neurotrophic factor (BDNF) and tryptophan hydroxylase 2 (TPH2) is well characterized to facilitate rapid and long-lasting antidepressant actions. Therefore, th
Externí odkaz:
https://doaj.org/article/c2a2f8e282624ca98581fb66783e7f9c
Autor:
Yaxin Guo, Nuo Chen, Ming Zhao, Baihui Cao, Faliang Zhu, Chun Guo, Yongyu Shi, Qun Wang, Yan Li, Lining Zhang
Publikováno v:
Pharmacological Research, Vol 202, Iss , Pp 107136- (2024)
CREB-regulated transcription coactivator 1 (CRTC1), a pivotal synaptonuclear messenger, regulates synaptic plasticity and transmission to prevent depression. Despite exhaustive investigations into CRTC1 mRNA reductions in the depressed mice, the regu
Externí odkaz:
https://doaj.org/article/9683cdaf52804edab520d7e8c21e83d2
Autor:
Chaoze Li, Mingsheng Zhao, Ming Zhao, Nuo Chen, Yaxin Guo, Yingxin Du, Yi Zhang, Baihui Cao, Bing Zhan, Chun Guo, Yuan Li, Yan Li, Yongyu Shi, Faliang Zhu, Lining Zhang, Qun Wang
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract White adipose tissue (WAT) homeostasis substantiated by type 2 immunity is indispensable to counteract obesity and metabolic disorders. IL-33/suppression of tumorigenicity (ST) 2 signaling promotes type 2 response in WAT, while potential reg
Externí odkaz:
https://doaj.org/article/4e3172de711a40158464c1d8cb580c85
Autor:
Xiao Zhuang, Bing Zhan, Yufeng Jia, Chaoze Li, Nan Wu, Ming Zhao, Nuo Chen, Yaxin Guo, Yingxin Du, Yi Zhang, Baihui Cao, Yan Li, Faliang Zhu, Chun Guo, Qun Wang, Yuan Li, Lining Zhang
Publikováno v:
Brain, behavior, and immunity. 102
Hyper-inflammatory reaction plays a crucial role in the pathophysiology of depression and anxiety disorders. However, the mechanisms underlying inflammation-induced anxiety changes remain poorly understood. Here, we showed that in the lipopolysacchar