Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Baiba Jansone"'
Publikováno v:
Medicina, Vol 60, Iss 4, p 658 (2024)
Background and Objectives. Neurogenesis is an integral process in post-stroke recovery, involving the recruitment of proliferating neuroblasts from neurogenic niches of the mammal brain. However, the role of neurogenesis in the long-term restoration
Externí odkaz:
https://doaj.org/article/1d1afc7cefde4584a8b682c4b7fba236
Autor:
Ksenija Lūcija Bahire, Reinis Maļuhins, Fiona Bello, Jolanta Upīte, Aleksandrs Makarovs, Baiba Jansone
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 416 (2024)
Cerebral ischemia/reperfusion (I/R) refers to a secondary brain injury that results in mitochondrial dysfunction of variable extent, leading to neuronal cell damage. The impact of this process has mainly been studied in the short term, from the early
Externí odkaz:
https://doaj.org/article/14dcbb2f41f24e318114eb06321d078c
Autor:
Vladimirs Pilipenko, Zane Dzirkale, Rebeka Rozkalne, Jolanta Upite, Farida Hellal, Nikolaus Plesnila, Baiba Jansone
Publikováno v:
Medicina, Vol 59, Iss 12, p 2168 (2023)
Background and Objectives: Dissecting the complex pathological cascade of an ischemic stroke in preclinical models is highly warranted to understand the course of this disease in humans. Neurogenesis and angiogenesis are integral for post-stroke reco
Externí odkaz:
https://doaj.org/article/c07da837e2604d8d93a64f029008e344
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1782 (2023)
Callosotomy is an invasive method that is used to study the role of interhemispheric functional connectivity in the brain. This surgical approach is technically demanding to perform in small laboratory animals, such as rodents, due to several methodo
Externí odkaz:
https://doaj.org/article/ce3d695c857548af896bee7b70e6e6ef
Autor:
Pablo Bascuñana, Mirjam Brackhan, Luisa Möhle, Jingyun Wu, Thomas Brüning, Ivan Eiriz, Baiba Jansone, Jens Pahnke
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 331 (2023)
Alzheimer’s disease (AD) is the most common cause of dementia. Fingolimod has previously shown beneficial effects in different animal models of AD. However, it has shown contradictory effects when it has been applied at early disease stages. Our ob
Externí odkaz:
https://doaj.org/article/d1485acc75c0483889a52eb3e8b18b7b
Autor:
Johannes Steffen, Markus Krohn, Christina Schwitlick, Thomas Brüning, Kristin Paarmann, Claus U. Pietrzik, Henrik Biverstål, Baiba Jansone, Oliver Langer, Jens Pahnke
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-9 (2017)
Abstract Amyloid-β (Aβ) deposition is one of the hallmarks of the amyloid hypothesis in Alzheimer’s disease (AD). Mouse models using APP-transgene overexpression to generate amyloid plaques have shown to model only certain parts of the disease. T
Externí odkaz:
https://doaj.org/article/316f833d2d054e82828c91fe072bb6e9
Publikováno v:
Forests, Vol 11, Iss 12, p 1260 (2020)
The annual shoot elongation could be described by a non-linear growth model to characterize differences in its dynamics among spruce genotypes, the effect of each shoot elongation phase on the total shoot length, and the genetic differences for a par
Externí odkaz:
https://doaj.org/article/209a5ded33ae4352b614b8e76ee49782
Publikováno v:
Molecules, Vol 25, Iss 8, p 1801 (2020)
The needles of conifer trees are one of the richest sources of natural polyprenols. Polyprenol homologs from Abies sibirica L. lipophilic 80% purified extract were analyzed and quantified. In total, 10 peaks (Prenol-11 to Prenol-20) were observed in
Externí odkaz:
https://doaj.org/article/356a07d1725e4fe99275590bb6dc2556
Autor:
Harry V. Vinters, Ruta Muceniece, Ivars Kalvinsh, Zane Dzirkale, Baiba Jansone, Simons Svirskis, Juris Rumaks, Sergejs Isajevs, Ulrika Beitnere, Jolanta Pupure, Darja Svirina, Vija Z. Klusa
Publikováno v:
International Journal of Molecular Sciences, Vol 11, Iss 11, Pp 4465-4487 (2010)
Previously, we have found that mildronate [3-(2,2,2-trimethylhydrazinium) propionate dihydrate], a small molecule with charged nitrogen and oxygen atoms, protects mitochondrial metabolism that is altered by inhibitors of complex I and has neuroprotec
Externí odkaz:
https://doaj.org/article/0e05f9ffda784911b96b671bac6aa682
Autor:
Baiba Jansone, Inga Kadish, Thomas van Groen, Ulrika Beitnere, Doyle Ray Moore, Aiva Plotniece, Karlis Pajuste, Vija Klusa
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127686 (2015)
Ca2+ blockers, particularly those capable of crossing the blood-brain barrier (BBB), have been suggested as a possible treatment or disease modifying agents for neurodegenerative disorders, e.g., Alzheimer's disease. The present study investigated th
Externí odkaz:
https://doaj.org/article/47d93e6428bc4fb081ec3b3e1d5e76dd