Pharmacokinetic mechanisms underlying the detoxification effect of Glycyrrhizae Radix et Rhizoma (Gancao): drug metabolizing enzymes, transporters, and beyond

Autor: Ting Zhou, Ji-Quan Zhang, Fei Wu, Qing Zhao, Na Li, Bai-Can Yang, Rui Wang, Bing-Liang Ma

Publikováno v: Expert Opinion on Drug Metabolism & Toxicology. 15:167-177

Glycyrrhizae Radix et Rhizoma (Gancao in Chinese) is the most frequently used traditional Chinese medicine (TCM) owing to its various pharmacological effects and, more importantly, the synergistic effects that enhance the efficacy and reduce the toxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938e44d340c482bb8297ad01b4a66a54
https://doi.org/10.1080/17425255.2019.1563595

A Compositive Strategy to Study the Pharmacokinetics of TCMs: Taking Coptidis Rhizoma, and Coptidis Rhizoma-Glycyrrhizae Radix et Rhizoma as Examples

Autor: Min Zheng, Ji-Quan Zhang, Yueming Ma, Yan Yang, Rui Wang, Bai-Can Yang, Na Li, Yuan-Yuan Li, Ting Zhou, Qiao Li, Fei Wu, Bing-Liang Ma

Publikováno v: Molecules, Vol 23, Iss 8, p 2042 (2018)
Molecules
Volume 23
Issue 8
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

Pharmacokinetic studies are crucial for elucidating the effective constituents and formula compatibility of traditional Chinese medicines (TCMs). However, studies have usually been limited to single dosages and detection of systemic blood concentrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed3292c30d26fd79d03348002c2fca8
http://www.mdpi.com/1420-3049/23/8/2042

In vitro and in vivo effects of rat kidney vascular endothelial cells on osteogenesis of rat bone marrow mesenchymal stem cells growing on polylactide-glycoli acid (PLGA) scaffolds

Autor: Bai-Can Yang, Hongchen Sun, Ying-Ying Guo, Guangxiang Zang, Zhe Qu

Publikováno v: BioMedical Engineering OnLine, Vol 6, Iss 1, p 41 (2007)
BioMedical Engineering

It is well established that vascularization is critical for osteogenesis. However, adequate vascularization also remains one of the major challenges in tissue engineering of bone. This problem is further accentuated in regeneration of large volume of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d336684af37cf05ec0482aefdaf20b2c
http://www.biomedical-engineering-online.com/content/6/1/41

Preparation of liposomal brucine and its pharmaceutical/pharmacodynamic characterization.

Autor: Xiang-qi Qin, Yuan Yuan, Chang-sheng Liu, Qiu-yun Wang, Xi Shen, Bai-can Yang

Publikováno v: Acta Pharmacologica Sinica; Nov2007, Vol. 28 Issue 11, p1851-1858, 8p, 1 Diagram, 6 Charts, 5 Graphs

A Compositive Strategy to Study the Pharmacokinetics of TCMs: Taking Coptidis Rhizoma, and Coptidis Rhizoma-Glycyrrhizae Radix et Rhizoma as Examples.

Autor: Li, Qiao¹, Yang, Yan¹, Zhou, Ting¹, Zheng, Min¹, Li, Yuan-Yuan¹, Ma, Yue-Ming¹, Ma, Bing-Liang¹, Wang, Rui², Zhang, Ji-Quan², Wu, Fei², Li, Na³, Yang, Bai-Can³

Publikováno v: Molecules. Aug2018, Vol. 23 Issue 8, p2042. 1p. 1 Diagram, 3 Charts, 1 Graph.