Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bahram Sharif-Askari"'
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 3, p 52 (2023)
Background: Poly(ADP-ribose) polymerases 1 and 2 (PARP1, 2), and 3 mediate protein modifications that facilitate the recruitment of DNA repair factors to single and double strand breaks. PARP3 is unique in that it is also required for efficient mitot
Externí odkaz:
https://doaj.org/article/cacb7b9c614d447fbe6f2e1f9cfabee1
Autor:
Maja Krajinovic, Caroline Laverdière, Daniel Sinnett, Jeffery L. Kutok, Donna Neuberg, Stephen E. Sallan, Lewis B. Silverman, Malgorzata Labuda, Julie Rousseau, Vincent Gagné, Haithem Laaribi, Francesco Ceppi, Bahram Sharif-Askari, Mohsen Ben Tanfous
Purpose: Asparaginase (ASNase) is a standard and critical component in the therapy of childhood acute lymphoblastic leukemia (ALL), but it is also associated with several toxicities.Experimental design: We recently reported the results of an associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f9db41efb3ad5d9dce9153cc10fcba
https://doi.org/10.1158/1078-0432.c.6524865
https://doi.org/10.1158/1078-0432.c.6524865
Autor:
Maja Krajinovic, Caroline Laverdière, Daniel Sinnett, Jeffery L. Kutok, Donna Neuberg, Stephen E. Sallan, Lewis B. Silverman, Malgorzata Labuda, Julie Rousseau, Vincent Gagné, Haithem Laaribi, Francesco Ceppi, Bahram Sharif-Askari, Mohsen Ben Tanfous
PDF file - 80K, Polymorphisms in ATF5, ASNS and ASS1 genes analyzed in the relation to ASNase related complications.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f14d3e1c1a7c86b248e1b652eb6ef73
https://doi.org/10.1158/1078-0432.22461699.v1
https://doi.org/10.1158/1078-0432.22461699.v1
Autor:
Maja Krajinovic, Daniel Sinnett, Jeffery L. Kutok, Donna Neuberg, Lewis B. Silverman, Stephen E. Sallan, Francesco Ceppi, Caroline Laverdière, Ivan Brukner, Bahram Sharif-Askari, Malgorzata Labuda, Julie Rousseau, Vincent Gagné
Purpose: Corticosteroids induce apoptosis in the malignant lymphoid cells and are critical component of combination therapy for acute lymphoblastic leukemia (ALL). Several genome-wide microarray studies showed major implication of proapoptotic Bim in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d6694f03819ba767345af220fbbb91
https://doi.org/10.1158/1078-0432.c.6522252
https://doi.org/10.1158/1078-0432.c.6522252
Publikováno v:
Frontiers in Bioscience-Landmark. 28:52
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a43a53f8abf14a8e6afb7edcbcf3953
https://doi.org/10.31083/j.fbl2803052
https://doi.org/10.31083/j.fbl2803052
Publikováno v:
Breast Cancer Research and Treatment. 172:23-32
PARP-3 is member of the PARP family of poly (ADP-ribose) polymerases involved in ADPribosylation. PARPs are involved in the basic mechanisms of DNA repair. PARP3, a critical player for efficient mitotic progression, is required for the stabilization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e022f8732bed3b75eba44379ac048e81
https://doi.org/10.1007/s10549-018-4888-6
https://doi.org/10.1007/s10549-018-4888-6
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
In this work we explored metabolic aspects of human primary leukemic lymphocytes that hold a potential impact on the treatment of Bruton tyrosine kinase (BTK)-driven diseases. Our results suggest that there is crosstalk between Bruton tyrosine kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4845951a2975548786e7aad0a987d3
https://pubmed.ncbi.nlm.nih.gov/31363127
https://pubmed.ncbi.nlm.nih.gov/31363127
Publikováno v:
Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28c5fb8e26780f1245604fee8259d8df
https://doi.org/10.4267/2042/66069
https://doi.org/10.4267/2042/66069
Autor:
Francesco Ceppi, Haithem Laaribi, Maja Krajinovic, Jeffery L. Kutok, Mohsen Ben Tanfous, Julie Rousseau, Lewis B. Silverman, Malgorzata Labuda, Bahram Sharif-Askari, Caroline Laverdière, Vincent Gagné, Donna Neuberg, Daniel Sinnett, Stephen E. Sallan
Publikováno v:
Clinical Cancer Research. 21:329-334
Purpose: Asparaginase (ASNase) is a standard and critical component in the therapy of childhood acute lymphoblastic leukemia (ALL), but it is also associated with several toxicities. Experimental design: We recently reported the results of an associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d028b3cecf58e11ed20904e66777712a
https://doi.org/10.1158/1078-0432.ccr-14-0508
https://doi.org/10.1158/1078-0432.ccr-14-0508
Publikováno v:
Cancer Research. 79:300-300
Poly (ADP-ribose) polymerase (PARP) resulting poly (ADP-ribosyl)ation is an early player in modification of proteins detected at single strand breaks and double strand breaks contributing to DNA repair. PARP1, 2 and 3 are involved in this process. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1f903a8e45487c46c1d73154b363f7b
https://doi.org/10.1158/1538-7445.am2019-300
https://doi.org/10.1158/1538-7445.am2019-300