Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bahram Arezi"'
Autor:
Saharnaz Bigdeli, Bahram Arezi, Jan Godoski, Denise Rhodes, Ryan Aguilar, Karen William, Bernd Buehler, Ji Zhu, Ronda Allen
Publikováno v:
Cancer Research. 83:764-764
RNA-Seq is a revolutionary technology for transcriptome analysis, which has been used to quantify transcript levels, confirm gene annotation, identify novel transcripts, splice variants, and fusion detection. Traditionally, the usefulness of RNA-Seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3002136aa17847ff41c05d3213adc5df
https://doi.org/10.1158/1538-7445.am2023-764
https://doi.org/10.1158/1538-7445.am2023-764
Autor:
Tracy Liu, Carlos Pabon, Bahram Arezi, Ashutosh Ashutosh, Jimmy Jin, Heather Tao, Gilbert Amparo, Jayati Ghosh, Arjun Vadapalli, Akansha Khare, Linus Forsmark, Christian A. Le Cocq, Michael Ruvolo, Douglas N. Roberts
Publikováno v:
Cancer Research. 79:5119-5119
Background: The current standard of genomic profiling of cancer tissues relies upon multiple separate technologies to aid in tumor characterization. Here we describe a customizable NGS design and analysis workflow for cancer samples that can detect s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5fedcd07b1520d44680073415531faf
https://doi.org/10.1158/1538-7445.am2019-5119
https://doi.org/10.1158/1538-7445.am2019-5119
Autor:
Bahram Arezi, Holly H. Hogrefe
Publikováno v:
Nucleic Acids Research
In an effort to increase the thermostability of Moloney Murine Leukemia Virus reverse transcriptase (MMLV RT), we screened random and site-saturation libraries for variants that show increased resistance to thermal inactivation. We discovered five mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f78ed0d3988c1b7600be655afb35ae18
https://doi.org/10.1093/nar/gkn952
https://doi.org/10.1093/nar/gkn952
Publikováno v:
Journal of Molecular Biology. 322:719-729
We examined the molecular basis of ddNTP selectivity in archaeal family B DNA polymerases by randomly mutagenizing the gene encoding Thermococcus sp. JDF-3 DNA polymerase and screening mutant libraries for improved ddNTP incorporation. We identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68dbbe7ae20b75ff2fc6dac32106c76
https://doi.org/10.1016/s0022-2836(02)00843-4
https://doi.org/10.1016/s0022-2836(02)00843-4
Autor:
Gilbert Amparo, Keith Chen, Christian LeCocq, Brenda Rogers, Jayati Ghosh, Ashutosh Ashutosh, Carlos Pabon, Bilan Hsue, Bahram Arezi, Madhuvanthi Ramaiah, Holly H. Hogrefe
Publikováno v:
Cancer Research. 77:5347-5347
FFPE tissue archiving is the most widely used method for clinical sample preservation, and provides a valuable source of diverse genetic information for cancer biomarker discovery. NGS library preparation is often challenging, however, as FFPE-derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0b10318f7c0388d88e4db00ee1513f2
https://doi.org/10.1158/1538-7445.am2017-5347
https://doi.org/10.1158/1538-7445.am2017-5347
Autor:
Connie J. Hansen, Nancy McKinney, Keith Chen, Holly H. Hogrefe, Jennifer Lapira, Sarah Hamilton, Bahram Arezi, Jeffrey D. Fox, Michelle Cayouette
Publikováno v:
Frontiers in Microbiology, Vol 5 (2014)
Frontiers in Microbiology
Frontiers in Microbiology
Faster-cycling PCR formulations, protocols, and instruments have been developed to address the need for increased throughput and shorter turn-around times for PCR-based assays. Although run times can be cut by up to 50%, shorter cycle times have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302bf70bf77eec066d91581477b062d3
https://doi.org/10.3389/fmicb.2014.00408
https://doi.org/10.3389/fmicb.2014.00408
Publikováno v:
Analytical Biochemistry. 400:301-303
Inhibitor resistance of several commercial Moloney murine leukemia virus reverse transcriptase (MMLV RT) enzymes was investigated. IC(50) values were determined for potential RNA contaminants, including guanidine thiocyanate, ethanol, formamide, ethy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d08a220f61b0ecf80582a8e5a5b6a1b9
https://doi.org/10.1016/j.ab.2010.01.024
https://doi.org/10.1016/j.ab.2010.01.024
Autor:
Bahram Arezi, Robert D. Kuchta
Publikováno v:
Trends in Biochemical Sciences. 25:572-576
Eukaryotic DNA primase initiates the synthesis of all new DNA strands by synthesizing short RNA oligomers on single-stranded DNA. Additionally, primase helps couple replication and repair and is critical for telomere maintenance and, therefore, chrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff99045d7b8f0f9c9a9f6ec940ba444
https://doi.org/10.1016/s0968-0004(00)01680-7
https://doi.org/10.1016/s0968-0004(00)01680-7
Publikováno v:
Biochemistry. 38:12899-12907
Regulation of the p49-p58 primase complex during primer synthesis and the interaction of the primase subunits with DNA were examined. After primase synthesizes a primer that DNA polymerase alpha (pol alpha) can readily elongate, further primase activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4eb0f91a5b81b84c9e51449cce93deb
https://doi.org/10.1021/bi9908991
https://doi.org/10.1021/bi9908991
Autor:
Katie Leigh Zobeck, Christian LeCocq, Linus Forsmark, Bahram Arezi, Heather Tao, Henrik Johansson
Publikováno v:
Cancer Genetics. 209:296
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67f4eec9bbb32dd9908d1600b22d4946
https://doi.org/10.1016/j.cancergen.2016.04.041
https://doi.org/10.1016/j.cancergen.2016.04.041