Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Bahija, Jallal"'
Autor:
David A. Tice, Robert E. Hollingsworth, Ronald Herbst, Bahija Jallal, Philipp Steiner, Ping Tsui, Partha Chowdhury, Chunning Yang, Leslie Wetzel, Ray Rothstein, Hong Chen, Ravinder Tammali, Krista Kinneer, Kevin Schifferli, Rosa A. Carrasco, Zhan Xiao
HER3/ERBB3 is a kinase-deficient member of the EGFR family receptor tyrosine kinases (RTK) that is broadly expressed and activated in human cancers. HER3 is a compelling cancer target due to its important role in activation of the oncogenic PI3K/AKT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcc96583b01d461e7fb0468a7a88fa35
https://doi.org/10.1158/1535-7163.c.6538702.v1
https://doi.org/10.1158/1535-7163.c.6538702.v1
Autor:
David A. Tice, Robert E. Hollingsworth, Ronald Herbst, Bahija Jallal, Philipp Steiner, Ping Tsui, Partha Chowdhury, Chunning Yang, Leslie Wetzel, Ray Rothstein, Hong Chen, Ravinder Tammali, Krista Kinneer, Kevin Schifferli, Rosa A. Carrasco, Zhan Xiao
Figure 1: KTN3379 specifically binds to HER3; Figure 2: KTN3379 suppresses cell-growth in HRG-HER3 autocrine cells and HRGinduced VEGF secretion; Figure 3: KTN3379 arrests HER2+ breast cancer cells in G0/G1-phase; Figure 4: KTN3379 is inactive in HER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39380c21c500de7b31d46a26363070fb
https://doi.org/10.1158/1535-7163.22507480.v1
https://doi.org/10.1158/1535-7163.22507480.v1
Autor:
David A. Tice, Robert E. Hollingsworth, Ronald Herbst, Bahija Jallal, Philipp Steiner, Ping Tsui, Partha Chowdhury, Chunning Yang, Leslie Wetzel, Ray Rothstein, Hong Chen, Ravinder Tammali, Krista Kinneer, Kevin Schifferli, Rosa A. Carrasco, Zhan Xiao
Methods and figure legends for supplemental data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e19fb28b03753808f69ff05b3db5351
https://doi.org/10.1158/1535-7163.22507483
https://doi.org/10.1158/1535-7163.22507483
Autor:
Yong S. Chang, Klaus Bosslet, Steven Coats, Pamela A. Trail, Bahija Jallal, Mohammad Tabrizi, David C. Blakey, Margaret Veldman-Jones, Leonard Incognito, Sally-Ann Ricketts, Susan A. Cartlidge, Jon W. Chesebrough, Jin Gao
Insulin-like growth factors (IGF), IGF-I and IGF-II, are small polypeptides involved in regulating cell proliferation, survival, differentiation, and transformation. IGF activities are mediated through binding and activation of IGF-1R or insulin rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb8345c8c32b7a5ff614750b0575537f
https://doi.org/10.1158/0008-5472.c.6503096.v1
https://doi.org/10.1158/0008-5472.c.6503096.v1
Autor:
Yong S. Chang, Klaus Bosslet, Steven Coats, Pamela A. Trail, Bahija Jallal, Mohammad Tabrizi, David C. Blakey, Margaret Veldman-Jones, Leonard Incognito, Sally-Ann Ricketts, Susan A. Cartlidge, Jon W. Chesebrough, Jin Gao
Supplementary Figures 1-4, Tables 1-2 from Dual IGF-I/II–Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34542cf678ac0fd713a6e8f8c3d43ac8
https://doi.org/10.1158/0008-5472.22390904.v1
https://doi.org/10.1158/0008-5472.22390904.v1
Autor:
Liyan Jiang, Jiaqi Huang, Brandon W Higgs, Zhibin Hu, Zhan Xiao, Xin Yao, Sarah Conley, Haihong Zhong, Zheng Liu, Philip Brohawn, Dong Shen, Song Wu, Xiaoxiao Ge, Yue Jiang, Yizhuo Zhao, Yuqing Lou, Chris Morehouse, Wei Zhu, Yinong Sebastian, Meggan Czapiga, Vaheh Oganesyan, Haihua Fu, Yanjie Niu, Wei Zhang, Katie Streicher, David Tice, Heng Zhao, Meng Zhu, Lin Xu, Ronald Herbst, Xinying Su, Yi Gu, Shyoung Li, Lihua Huang, Jianren Gu, Baohui Han, Bahija Jallal, Hongbing Shen, Yihong Yao
Publikováno v:
PLoS Genetics, Vol 12, Iss 4, p e1005895 (2016)
Small cell lung cancer (SCLC) is an aggressive disease with poor survival. A few sequencing studies performed on limited number of samples have revealed potential disease-driving genes in SCLC, however, much still remains unknown, particularly in the
Externí odkaz:
https://doaj.org/article/5a94d0c0e61d478c84e2d5a2d8db5b34
Autor:
Jiaqi Huang, Chris Morehouse, Katie Streicher, Brandon W Higgs, Jin Gao, Meggan Czapiga, Anmarie Boutrin, Wei Zhu, Philip Brohawn, Yong Chang, Jaye Viner, Theresa LaVallee, Laura Richman, Bahija Jallal, Yihong Yao
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26177 (2011)
PURPOSE: Insulin-like growth factor (IGF) signaling through human insulin receptor isoform A (IR-A) contributes to tumorigenesis and intrinsic resistance to anti-IGF1R therapy. In the present study, we (a) developed quantitative TaqMan real time-PCR-
Externí odkaz:
https://doaj.org/article/bbcf5b03c12049078f8d5f6ebd89e2ef
Autor:
Yihong Yao, Laura Richman, Chris Morehouse, Melissa de los Reyes, Brandon W. Higgs, Anmarie Boutrin, Barbara White, Anthony Coyle, James Krueger, Peter A. Kiener, Bahija Jallal
Publikováno v:
PLoS ONE, Vol 4, Iss 3 (2009)
Externí odkaz:
https://doaj.org/article/4a4d1a9b85d548c28cbfcd4104728447
Autor:
Yihong Yao, Laura Richman, Chris Morehouse, Melissa de los Reyes, Brandon W Higgs, Anmarie Boutrin, Barbara White, Anthony Coyle, James Krueger, Peter A Kiener, Bahija Jallal
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2737 (2008)
BACKGROUND: Psoriasis is an immune-mediated disease characterized by aberrant epidermal differentiation, surface scale formation, and marked cutaneous inflammation. To better understand the pathogenesis of this disease and identify potential mediator
Externí odkaz:
https://doaj.org/article/6656647cca6841ab9c2874f8e6592ec6
Autor:
Carlos Bais, Katie Streicher, Bahija Jallal, James Conway, Hao Liu, Rajiv Raja, Philip Brohawn, Mike Kuziora, Song Wu, Young S. Lee, Brandon W. Higgs, Koustubh Ranade, Sriram Sridhar
Publikováno v:
Pharmaceutical Medicine. 31:217-233
Molecular biomarkers are increasingly being used to identify subgroups of patients that have a higher chance of benefiting from targeted therapies. Identification of predictive biomarkers and development of companion diagnostics to accompany targeted