Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Bahareh Behrouz"'
Autor:
Ryan Traynor, Jennifer Moran, Michael Stevens, Axel Knebel, Bahareh Behrouz, Kalpana Merchant, C. James Hastie, Paul Davies, Miratul M. K. Muqit, Virginia De Cesare
Parkinson’s disease (PD) is a progressive neurological disorder that manifests clinically as alterations in movement (bradykinesia, postural instability, loss of balance, and resting tremors) as well as multiple non-motor symptoms including but not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860152ff160f8865fe516b08cc35f28b
https://doi.org/10.1101/2022.03.04.482851
https://doi.org/10.1101/2022.03.04.482851
Autor:
Seung-Hoon Baek, Bahareh Behrouz, Johan Sunryd, Marianne Huebner, Samuel S. Pappas, John L. Goudreau, Keith J. Lookingland, Matthew J. Benskey
Publikováno v:
NeuroToxicology. 33:321-331
Hypothalamic tuberoinfundibular dopamine (TIDA) neurons remain unaffected in Parkinson disease (PD) while there is significant degeneration of midbrain nigrostriatal dopamine (NSDA) neurons. A similar pattern of susceptibility is observed in acute an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788aed5d83011a9c067f0a90ed09991d
https://doi.org/10.1016/j.neuro.2012.02.001
https://doi.org/10.1016/j.neuro.2012.02.001
Autor:
Owen A. Ross, Alex Rajput, Bahareh Behrouz, Zbigniew K. Wszolek, Jennifer M. Kachergus, Elan D. Louis, Nancy N. Diehl, Carles Vilariño-Güell, Christian Wider, Barbara Jasinska-Myga, Claudia M. Testa, Matthew J. Farrer, Alexandra I. Soto-Ortolaza, Ryan J. Uitti, Lorraine N. Clark, Stephanie A. Cobb, Joseph Jankovic, Michael G. Heckman
Publikováno v:
Neurogenetics, vol. 11, no. 4, pp. 401-408
Genetic variation in the leucine-rich repeat and Ig domain containing 1 gene (LINGO1) was recently associated with an increased risk of developing essential tremor (ET) and Parkinson disease (PD). Herein, we performed a comprehensive study of LINGO1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8f4ee135098d58318d944249f11160
https://doi.org/10.1007/s10048-010-0241-x
https://doi.org/10.1007/s10048-010-0241-x
Autor:
Robert E. Drolet, Kelly L. Janis, Keith J. Lookingland, Sarah K. Kaufman, John L. Goudreau, Ryan T. Brennan, Bahareh Behrouz
Publikováno v:
Journal of Alzheimer's Disease. 15:97-107
The objective of this study was to determine if the phosphodiesterase 5 (PDE-5) inhibitor, sildenafil, could be used as a neuroprotective agent in a chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) murine model of Parkinson's disease. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587f6310fbd3ed939495f61ef2027a30
https://doi.org/10.3233/jad-2008-15108
https://doi.org/10.3233/jad-2008-15108
Publikováno v:
Neuroscience. 147:592-598
Tuberoinfundibular dopamine (TIDA) neurons are spared in Parkinson's disease (PD), a disorder that causes degeneration of midbrain nigrostriatal dopamine (NSDA) and mesolimbic dopamine (MLDA) neurons. This pattern of susceptibility has been demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd7091cebdfd175c83e42a9767076ff
https://doi.org/10.1016/j.neuroscience.2007.05.007
https://doi.org/10.1016/j.neuroscience.2007.05.007
Autor:
Paul Davies, Matthew J. Farrer, Eugenia Trushina, Liang Zhang, Bahareh Behrouz, Heather L. Melrose, Sarah Lincoln, Pamela J. McLean, T.A. Christenson, Andreas S. Schroeder, Mei Yue, John D. Fryer, Kelly M. Hinkle, Erin E. Bowles, Joel E. Beevers, Fabienne C. Fiesel, Aishe Kurti, Dennis W. Dickson, Austen J. Milnerwood, Wolfdieter Springer
Publikováno v:
Neurobiology of Disease, Vol 78, Iss, Pp 172-195 (2015)
Mutations in the LRRK2 gene represent the most common genetic cause of late onset Parkinson's disease. The physiological and pathological roles of LRRK2 are yet to be fully determined but evidence points towards LRRK2 mutations causing a gain in kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d73e694ee6a45a335775722f03599e
https://pubmed.ncbi.nlm.nih.gov/25836420
https://pubmed.ncbi.nlm.nih.gov/25836420
Publikováno v:
Journal of Neurochemistry. 96:950-959
Tyrosine hydroxylase (TH) protein, phosphorylated at serine-40, serine-31 and serine-19, and enzyme catalytic activity were compared under basal conditions and in activated nigrostriatal dopamine (NSDA) neurons of wild-type and homozygous alpha-synuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58538fc8bdbd9cbe0bffd88728bee233
https://doi.org/10.1111/j.1471-4159.2005.03606.x
https://doi.org/10.1111/j.1471-4159.2005.03606.x
Autor:
Keith J. Lookingland, John L. Goudreau, Andreas F. Lehner, Barbara L. F. Kaplan, Norbert E. Kaminski, Kelly L. Janis, Alison K. McClure, Bahareh Behrouz, Tyrell J. Simkins, Samuel S. Pappas
Publikováno v:
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 7(3)
Motor dysfunctions of Parkinson Disease (PD) are due to the progressive loss of midbrain nigrostriatal dopamine (NSDA) neurons. Evidence suggests a role for cannabinoid receptors in the neurodegeneration of these neurons following neurotoxicant-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b13e44716939d9070383343ed9b6394
https://pubmed.ncbi.nlm.nih.gov/22639229
https://pubmed.ncbi.nlm.nih.gov/22639229
Autor:
Justus C. Dachsel, Wen Lang Lin, Beate Winner, Matthew J. Farrer, Kenya Nishioka, Bahareh Behrouz, Sarah Lincoln, Joel E. Beevers, Brittany N. Dugger, Iryna Prots, Kelly M. Hinkle, Mei Yue, Erin E. Bowles, Dennis W. Dickson, Heather L. Melrose, Caroline Kent, Christopher Janus
Publikováno v:
Molecular Neurodegeneration
Hinkle, KM; Yue, M; Behrouz, B; Dächsel, JC; Lincoln, SJ; Bowles, EE; et al.(2012). LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors. Molecular Neurodegeneration, 7(1). doi: 10.1186/1750-1326-7-25. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/4974v1qs
Molecular neurodegeneration, vol 7, iss 1
Molecular Neurodegeneration, Vol 7, Iss 1, p 25 (2012)
Hinkle, KM; Yue, M; Behrouz, B; Dächsel, JC; Lincoln, SJ; Bowles, EE; et al.(2012). LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors. Molecular Neurodegeneration, 7(1). doi: 10.1186/1750-1326-7-25. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/4974v1qs
Molecular neurodegeneration, vol 7, iss 1
Molecular Neurodegeneration, Vol 7, Iss 1, p 25 (2012)
Mutations in the LRRK2 gene are the most common cause of genetic Parkinson’s disease. Although the mechanisms behind the pathogenic effects of LRRK2 mutations are still not clear, data emerging from in vitro and in vivo models suggests roles in reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db6212b8688d146842ba88c0c531313
Autor:
Sarah Lincoln, Elizabeth Conibear, Behrouz Bahareh Behrouz, Ali H. Rajput, Joseph Ghika, Stephanie A. Cobb, Carles Vilariño-Güell, Greggory J. Wilhoite, Wyeth W. Wasserman, Jan O. Aasly, François Vingerhoets, Zbigniew K. Wszolek, Christian Wider, Anna Krygowska-Wajs, Alexandra I. Soto-Ortolaza, Ruth Djaldetti, Justus C. Dachsel, Fayçal Hentati, Ruey-Meei Wu, Andreas Puschmann, Heather L. Melrose, Owen A. Ross, Pierre R. Burkhard, Justin A. Bacon, Emna Hentati, Matthew J. Farrer, Alessandra Solida, Timothy Lynch, Daniel M. Evans, Alex Rajput, Jennifer M. Kachergus, Ryan J. Uitti, Eldad Melamed
Publikováno v:
American Journal of Human Genetics, Vol. 89, No 1 (2011) pp. 162-7
The identification of genetic causes for Mendelian disorders has been based on the collection of multi-incident families, linkage analysis, and sequencing of genes in candidate intervals. This study describes the application of next-generation sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d3fb9a990dbbb06aa1241373a71347