Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bahareh Badrian"'
Autor:
Cecilia M. Prêle, Thomas Iosifidis, Robin J. McAnulty, David R. Pearce, Bahareh Badrian, Tylah Miles, Sarra E. Jamieson, Matthias Ernst, Philip J. Thompson, Geoffrey J. Laurent, Darryl A. Knight, Steven E. Mutsaers
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 498 (2021)
The interleukin (IL)-6 family of cytokines and exaggerated signal transducer and activator of transcription (STAT)3 signaling is implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis, but the mechanisms regulating STAT3 expression and functi
Externí odkaz:
https://doaj.org/article/f48fa198e8004c7484e59b7e0c37a1fd
Autor:
Geoffrey J. Laurent, Philip J. Thompson, David R. Pearce, Sarra E. Jamieson, Matthias Ernst, Tylah Miles, Cecilia M Prêle, Robin J. McAnulty, Darryl A. Knight, Bahareh Badrian, Steven E. Mutsaers, Thomas Iosifidis
Publikováno v:
Biomedicines, Vol 9, Iss 498, p 498 (2021)
Biomedicines
Volume 9
Issue 5
Biomedicines
Volume 9
Issue 5
The interleukin (IL)-6 family of cytokines and exaggerated signal transducer and activator of transcription (STAT)3 signaling is implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis, but the mechanisms regulating STAT3 expression and functi
Publikováno v:
Oncotarget
Malignant mesothelioma is an aggressive and often fatal cancer associated with asbestos exposure. The disease originates in the mesothelial lining of the serosal cavities, most commonly affecting the pleura. Survival rates are low as diagnosis often
Autor:
Bahareh Badrian, Y. C. Gary Lee, Steven E. Mutsaers, Kimberly A Birnie, Cecilia M. Prêle, Deirdre B. Fitzgerald, Philip J. Thompson, Arthur W. Musk, Nicholas de Klerk, Jenette Creaney, Richard J.N. Allcock
Publikováno v:
Disease Markers
Disease Markers, Vol 2019 (2019)
Disease Markers, Vol 2019 (2019)
Malignant pleural mesothelioma (MPM) is an incurable cancer of the pleura that can be difficult to diagnose. Biomarkers for an easier and/or earlier diagnosis are needed. Approximately 90% of MPM patients develop a pleural effusion (PE). PEs are idea
Autor:
Yan Y. Yip, Kimberly A Birnie, Dominic C.H. Ng, Michaela B. Kirschner, Cecilia M. Prêle, Bahareh Badrian, Philip J. Thompson, Steven E. Mutsaers, Y. C. Gary Lee, Glen Reid, Arthur W. Musk
Publikováno v:
Molecular Cancer Research. 13:1106-1118
Malignant pleural mesothelioma (MPM) is often fatal, and studies have revealed that aberrant miRNAs contribute to MPM development and aggressiveness. Here, a screen of miRNAs identified reduced levels of miR-223 in MPM patient specimens. Interestingl
Autor:
Cecilia M. Prêle, GJ Laurent, Philip J. Thompson, Bahareh Badrian, Thomas Iosifidis, Steven E. Mutsaers, Darryl A. Knight, Sarra E. Jamieson, Matthias Ernst, Robin J. McAnulty, David Pearce
Publikováno v:
QJM: An International Journal of Medicine.
Autor:
Sarra E. Jamieson, Matthias Ernst, Geoffrey J. Laurent, Bahareh Badrian, Philip J. Thompson, Robin J. McAnulty, Cecilia M. Prêle, David Pearce, Thomas Iosifidis, Steven E. Mutsaers, Darryl A. Knight
Publikováno v:
ERS Lung Science Conference 2016.
The STAT inhibitor, SOCS1 is reduced in IPF lung fibroblasts, and has been linked to higher levels of type I collagen. Using IPF (n=6) and control (n=9) lung fibroblast cultures and control (n=4) and IPF (n=8) lung tissue, we investigated the mechani
Autor:
Bruce W. S. Robinson, Nicola J. Armstrong, J. James B. Edelman, Brian C. McCaughan, Michael P. Vallely, Arthur W. Musk, Steven E. Mutsaers, Bahareh Badrian, Steven Kao, Sonja Klebe, Nico van Zandwijk, Michaela B. Kirschner, Yuen Yee Cheng, Glen Reid, Jenette Creaney
Publikováno v:
Journal of Thoracic Oncology. 7:1184-1191
Introduction: We investigated the ability of cell-free microRNAs (miRNAs) in plasma and serum to serve as a biomarker for malignant mesothelioma (MM). Methods: Using miRNA microarrays, we profiled plasma samples from MM patients and healthy controls.
Autor:
Ivan Hong Wee Ng, Dominic C.H. Ng, Christopher Semsarian, Yvonne Y C Yeap, Tatiana Tsoutsman, Julie R. McMullen, Bahareh Badrian, Marie A. Bogoyevitch
Publikováno v:
Journal of Biological Chemistry. 286:1576-1587
Excessive proliferation and stabilization of the microtubule (MT) array in cardiac myocytes can accompany pathological cardiac hypertrophy, but the molecular control of these changes remains poorly characterized. In this study, we examined MT stabili
Autor:
Marie A. Bogoyevitch, Amardeep S. Dhillon, Bahareh Badrian, Dominic C.H. Ng, Steven E. Mutsaers, Ivan Hong Wee Ng, Yan Y. Yip, Yvonne Y C Yeap, John Silke, Tuong-Vi Nguyen
Publikováno v:
Biochemical Journal. 430:345-354
The JNKs (c-Jun N-terminal kinases) are stress-activated serine/threonine kinases that can regulate both cell death and cell proliferation. We have developed a cell system to control JNK re-expression at physiological levels in JNK1/2-null MEFs (muri