Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bahar Demirdirek"'
Autor:
John M. Wasylyk, Gregory Barker, Ajit S. Narang, Monica L. Adams, Bahar Demirdirek, Sibylle Herzer, Rajesh B. Gandhi, Daniel Fichana, Matthew McGann, Wenkui Lan, Smeet Deshmukh, Limin Zhang, John D. Fiske, Mary Elizabeth Krause
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 131:60-69
High concentration protein solutions are generally produced by spin column concentration (SCC) during early development and by tangential flow filtration (TFF) during later stages, when greater quantities of protein become available. This is based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c478a696185792b09ad7b46fbcc3486
https://doi.org/10.1016/j.ejpb.2018.07.014
https://doi.org/10.1016/j.ejpb.2018.07.014
Autor:
Bahar Demirdirek, Kathryn E. Uhrich
Publikováno v:
Journal of Bioactive and Compatible Polymers. 33:224-236
Physically crosslinked hydrogels were developed via solvent casting methods using a temperature-sensitive polymer, poly( N-isopropylacrylamide- co-acrylic acid), and a therapeutic polymer, salicylate-based poly(anhydride-esters), to concurrently rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97209442b3a37bca961d2ea01e9bc143
https://doi.org/10.1177/0883911517721070
https://doi.org/10.1177/0883911517721070
Autor:
Joseph J. Valente, Wei Ding, Wenkui Lan, Bahar Demirdirek, Difei Qiu, Lavanya K. Iyer, Mark S. Bolgar
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1105
Intravenous (IV) infusion of therapeutic proteins typically involves dilution of the formulated product into infusion media such as normal saline or dextrose, 5% m/v in water. We report results from a rigorous evaluation of imaged capillary isoelectr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b028f356775e2e792a00b7e0934c58
https://pubmed.ncbi.nlm.nih.gov/30594826
https://pubmed.ncbi.nlm.nih.gov/30594826
Autor:
Kathryn E. Uhrich, Bahar Demirdirek
Publikováno v:
Journal of Drug Targeting. 23:716-724
Salicylic acid (SA)-based physically crosslinked pH-sensitive hydrogels were developed for oral insulin delivery using various ratios of salicylate-based poly(anhydride-ester) and poly(acrylic acid) (PAA). Pore size, swelling behavior, insulin loadin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87bcbba34c6566c68aae10dde952d8e
https://doi.org/10.3109/1061186x.2015.1073293
https://doi.org/10.3109/1061186x.2015.1073293
Publikováno v:
Polymers for Biomedicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f655f0eef02831142b26110a407a238b
https://doi.org/10.1002/9781118967904.ch12
https://doi.org/10.1002/9781118967904.ch12
Autor:
Bahar Demirdirek, Kathryn E. Uhrich
Publikováno v:
International journal of pharmaceutics. 528(1-2)
In this work, salicylic acid (SA), a non-steroidal anti-inflammatory, was chemically incorporated into hydrogel systems to achieve sustained SA release profiles. With its anti-inflammatory properties, sustained release of SA would be relevant for tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33caff115d7235c669e09101c28e0ee9
https://pubmed.ncbi.nlm.nih.gov/28559214
https://pubmed.ncbi.nlm.nih.gov/28559214
Autor:
David E. Orban, Bahar Demirdirek, Leilani S. del Rosario, Alexander M. Harmon, Kathryn E. Uhrich
Publikováno v:
Macromolecular Bioscience. 10:415-423
Amphiphilic macromolecules (AMs) have unique branched hydrophobic domains attached to linear PEG chains. AMs self-assemble in aqueous solution to form micelles that are hydrolytically stable in physiological conditions (37 degrees C, pH 7.4) over 4 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc6b9d377af503801b6fe6b07608639d
https://doi.org/10.1002/mabi.200900335
https://doi.org/10.1002/mabi.200900335
Publikováno v:
Acta Biomaterialia. 5:883-892
Two classes of amphiphilic macromolecules were evaluated for drug delivery applications: those that exist as unimolecular micelles and those that self-assemble in aqueous solution to form micelles. This study compares the poly(ethylene glycol) (PEG)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae315742404b0d83e686c7807cc3237
https://doi.org/10.1016/j.actbio.2008.10.019
https://doi.org/10.1016/j.actbio.2008.10.019
Autor:
Leilani S, del Rosario, Bahar, Demirdirek, Alexander, Harmon, David, Orban, Kathryn E, Uhrich
Publikováno v:
Macromolecular bioscience. 10(4)
Amphiphilic macromolecules (AMs) have unique branched hydrophobic domains attached to linear PEG chains. AMs self-assemble in aqueous solution to form micelles that are hydrolytically stable in physiological conditions (37 degrees C, pH 7.4) over 4 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59638f0c1ee24849b10519c4b763c84b
https://pubmed.ncbi.nlm.nih.gov/20127669
https://pubmed.ncbi.nlm.nih.gov/20127669
Publikováno v:
Acta biomaterialia. 6(8)
A family of anionic nanoscale polymers based on amphiphilic macromolecules (AMs) was developed for controlled inhibition of highly oxidized low-density lipoprotein (hoxLDL) uptake by inflammatory macrophage cells, a process that triggers the escalati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1494bb80f358e6b1a248c824113b97e6
https://pubmed.ncbi.nlm.nih.gov/20170758
https://pubmed.ncbi.nlm.nih.gov/20170758