Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Bahar Ahani"'
Autor:
Gustavo H. Kijak, Bahar Ahani, Douglas Arbetter, Fernando Chuecos, Vancheswaran Gopalakrishnan, Jagadish Beloor, Tyler Brady, Amy Nguyen, Tiffany L. Roe, Nicolette Schuko, Tianhui Zhang, F. D. Richard Hobbs, Francisco Padilla, Elizabeth J. Kelly, Hugh Montgomery, Katie Streicher
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 12, Pp 2691-2707 (2023)
Abstract Introduction AZD7442 (tixagevimab/cilgavimab) comprises neutralising monoclonal antibodies (mAbs) that bind to distinct non-overlapping epitopes on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein. Viral evoluti
Externí odkaz:
https://doaj.org/article/81d8ce3337a543ba897387fe3803d1b4
Autor:
Bahar Ahani, Kevin M. Tuffy, Anastasia A. Aksyuk, Deidre Wilkins, Michael E. Abram, Ron Dagan, Joseph B. Domachowske, Johnathan D. Guest, Hong Ji, Anna Kushnir, Amanda Leach, Shabir A. Madhi, Vaishali S. Mankad, Eric A. F. Simões, Benjamin Sparklin, Scott D. Speer, Ann Marie Stanley, David E. Tabor, Ulrika Wählby Hamrén, Elizabeth J. Kelly, Tonya Villafana
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/62972434e0cc4edfafbaf60c3024f8ec
Autor:
Bahar Ahani, Kevin M. Tuffy, Anastasia A. Aksyuk, Deidre Wilkins, Michael E. Abram, Ron Dagan, Joseph B. Domachowske, Johnathan D. Guest, Hong Ji, Anna Kushnir, Amanda Leach, Shabir A. Madhi, Vaishali S. Mankad, Eric A. F. Simões, Benjamin Sparklin, Scott D. Speer, Ann Marie Stanley, David E. Tabor, Ulrika Wählby Hamrén, Elizabeth J. Kelly, Tonya Villafana
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Nirsevimab is a monoclonal antibody that binds to the respiratory syncytial virus (RSV) fusion protein. During the Phase 2b (NCT02878330) and MELODY (NCT03979313) clinical trials, infants received one dose of nirsevimab or placebo before the
Externí odkaz:
https://doaj.org/article/fb9efa8bfa3c458ebbb25e11a772eeb6
Autor:
Jill Maaske, Stephanie Sproule, Ann R. Falsey, Magdalena E. Sobieszczyk, Anne F. Luetkemeyer, Grant C. Paulsen, Sharon A. Riddler, Merlin L. Robb, Charlotte-Paige Rolle, Beverly E. Sha, Tina Tong, Bahar Ahani, Anastasia A. Aksyuk, Himanshu Bansal, Timothy Egan, Brett Jepson, Marcelino Padilla, Nirmeshkumar Patel, Kathryn Shoemaker, Ann Marie Stanley, Phillip A. Swanson, Deidre Wilkins, Tonya Villafana, Justin A. Green, Elizabeth J. Kelly
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
BackgroundBreakthrough severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in coronavirus disease 2019 (COVID-19) vaccinees typically produces milder disease than infection in unvaccinated individuals.MethodsTo explore disease atte
Externí odkaz:
https://doaj.org/article/a7f99999dfa54de681877a3fca396db9
Autor:
Bethany Dearlove, Sodsai Tovanabutra, Christopher L Owen, Eric Lewitus, Yifan Li, Eric Sanders-Buell, Meera Bose, Anne-Marie O'Sullivan, Gustavo Kijak, Shana Miller, Kultida Poltavee, Jenica Lee, Lydia Bonar, Elizabeth Harbolick, Bahar Ahani, Phuc Pham, Hannah Kibuuka, Lucas Maganga, Sorachai Nitayaphan, Fred K Sawe, Jerome H Kim, Leigh Anne Eller, Sandhya Vasan, Robert Gramzinski, Nelson L Michael, Merlin L Robb, Morgane Rolland, RV217 Study Team
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008537 (2021)
While large datasets of HIV-1 sequences are increasingly being generated, many studies rely on a single gene or fragment of the genome and few comparative studies across genes have been done. We performed genome-based and gene-specific Bayesian phylo
Externí odkaz:
https://doaj.org/article/b0c174c950ec4182833e083b931ec6e3
Autor:
Morgane Rolland, Sodsai Tovanabutra, Bethany Dearlove, Yifan Li, Christopher L Owen, Eric Lewitus, Eric Sanders-Buell, Meera Bose, AnneMarie O'Sullivan, Raabya Rossenkhan, Jan Phillipus Lourens Labuschagne, Paul T Edlefsen, Daniel B Reeves, Gustavo Kijak, Shana Miller, Kultida Poltavee, Jenica Lee, Lydia Bonar, Elizabeth Harbolick, Bahar Ahani, Phuc Pham, Hannah Kibuuka, Lucas Maganga, Sorachai Nitayaphan, Fred K Sawe, Leigh Anne Eller, Robert Gramzinski, Jerome H Kim, Nelson L Michael, Merlin L Robb, RV217 Study Team
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008179 (2020)
Most HIV-1 infected individuals do not know their infection dates. Precise infection timing is crucial information for studies that document transmission networks or drug levels at infection. To improve infection timing, we used the prospective RV217
Externí odkaz:
https://doaj.org/article/4eba0f9f21794581ba1e24b1058d88ef
Autor:
Hongshuai Li, Arvydas Usas, Minakshi Poddar, Chien-Wen Chen, Seth Thompson, Bahar Ahani, James Cummins, Mitra Lavasani, Johnny Huard
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64923 (2013)
Human muscle-derived progenitor cells (hMDPCs) offer great promise for muscle cell-based regenerative medicine; however, prolonged ex-vivo expansion using animal sera is necessary to acquire sufficient cells for transplantation. Due to the risks asso
Externí odkaz:
https://doaj.org/article/53815707611840a5b5073b7eb406e213
Autor:
Deidre Wilkins, Annefleur C Langedijk, Robert Jan Lebbink, Christopher Morehouse, Michael E Abram, Bahar Ahani, Anastasia A Aksyuk, Eugenio Baraldi, Tyler Brady, Albert Tian Chen, Hsin Chi, Eun Hwa Choi, Robert Cohen, Daria M Danilenko, Vancheswaran Gopalakrishnan, Anne Greenough, Terho Heikkinen, Mitsuaki Hosoya, Christian Keller, Elizabeth J Kelly, Leyla Kragten-Tabatabaie, Federico Martinón-Torres, Abiel Homero Mascareñas de Los Santos, Marta C Nunes, María Angélica Palomino, Jesse Papenburg, Jeffrey M Pernica, Peter Richmond, Renato T Stein, Kevin M Tuffy, Charl Verwey, Mark T Esser, David E Tabor, Louis J Bont, Pascale Clement, Atul Gupta, Koichi Hashimoto, Kseniya Komissarova, Matt Laubscher, Magali Lumertz, Elena Priante, Irene Rivero-Calle, Ushma Wadia, Ki Wook Yun
Publikováno v:
The Lancet Infectious Diseases.
Autor:
Magdalena E Sobieszczyk, Ann R Falsey, Anne F Luetkemeyer, Grant C Paulsen, Sharon A Riddler, Merlin L Robb, Charlotte-Paige M Rolle, Beverly E Sha, Tina Tong, Bahar Ahani, Anastasia A Aksyuk, Himanshu Bansal, Justin A Green, Brett Jepson, Jill Maaske, Kathryn Shoemaker, Stephanie Sproule, Ann Marie Stanley, Deidre Wilkins, Tonya L Villafana, Elizabeth J Kelly
Publikováno v:
Open Forum Infectious Diseases. 9
Background Breakthrough infections post-COVID-19 vaccination increase with waning immunity and typically produce milder disease than infections in unvaccinated individuals. We investigated immuno-virologic responses and COVID-19 symptom burden upon b
Autor:
Kevin M Tuffy, Michael E Abram, Tiffany L Roe, Bahar Ahani, Tyler Brady, Nicolette Schuko, Lori Clarke, Carolina Caceres, Tara Kenny, Virginia Takahashi, Tianhui Zhang, David E Tabor, Gustavo H Kijak, Elizabeth J Kelly, Katie Streicher
Publikováno v:
Open Forum Infectious Diseases. 9
Background AZD7442 is a combination of extended–half-life SARS-CoV-2–neutralizing monoclonal antibodies (tixagevimab/cilgavimab) that bind to distinct epitopes on the SARS-CoV-2 spike protein. In the PROVENT study, a single 300 mg intramuscular d