Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Bahaa Jawad"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1288-1301 (2021)
The COVID-19 pandemic poses a severe threat to human health with an unprecedented social and economic disruption. Spike (S) glycoprotein of the SARS-CoV-2 virus is pivotal in understanding the virus anatomy, since it initiates the first contact with
Externí odkaz:
https://doaj.org/article/a4690cd57b724fae8216f319f11161b6
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 517 (2023)
The spike protein (S-protein) is a crucial part of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with its many domains responsible for binding, fusion, and host cell entry. In this review we use the density functional theory (DFT)
Externí odkaz:
https://doaj.org/article/564f8108e44f4dcd9f4dd4435059c8bd
Publikováno v:
Microorganisms, Vol 10, Iss 10, p 1999 (2022)
The attachment of the spike protein in SARS-CoV-2 to host cells and the initiation of viral invasion are two critical processes in the viral infection and transmission in which the presence of unique furin (S1/S2) and TMPRSS2 (S2′) cleavage sites p
Externí odkaz:
https://doaj.org/article/2380ed3fe2bb4312920692b8dc221054
Publikováno v:
Viruses, Vol 14, Iss 3, p 465 (2022)
The SARS-CoV-2 Delta variant is emerging as a globally dominant strain. Its rapid spread and high infection rate are attributed to a mutation in the spike protein of SARS-CoV-2 allowing for the virus to invade human cells much faster and with an incr
Externí odkaz:
https://doaj.org/article/68e696eacc684e9d93696a2b2ecd3792
The emergence of Omicron SARS-CoV-2 subvariants (BA.1, BA.2, BA.4, and BA.5) with an unprecedented number of mutations in their receptor-binding domain (RBD) of the spike-protein has fueled a new surge of COVID-19 infections, posing a major challenge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d2e49dfd426c55de90bdab48e9858f1
https://doi.org/10.1101/2022.12.25.521903
https://doi.org/10.1101/2022.12.25.521903
Publikováno v:
The journal of physical chemistry letters. 13(17)
The emergence of new SARS-CoV-2 Omicron variant of concern (OV) has exacerbated the COVID-19 pandemic because of a large number of mutations in the spike protein, particularly in the receptor-binding domain (RBD), resulting in highly contagious and/o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0abf89616e10394fe0f5bed47828f0b
https://pubmed.ncbi.nlm.nih.gov/35481766
https://pubmed.ncbi.nlm.nih.gov/35481766
Publikováno v:
The Journal of Physical Chemistry B. 124:7803-7818
Doxorubicin (DOX) is a cancer drug that binds to dsDNA through intercalation. A comprehensive microsecond timescale molecular dynamics study is performed for DOX with 16 tetradecamer dsDNA sequences in explicit aqueous solvent, in order to investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fea1c6297554dbcfe25d8482931fe3d
https://doi.org/10.1021/acs.jpcb.0c05840
https://doi.org/10.1021/acs.jpcb.0c05840
Emergence of new SARS-CoV-2 Omicron VOC (OV) has exacerbated the COVID-19 pandemic due to a large number of mutations in the spike-protein, particularly in the receptor-binding domain (RBD), resulting in highly contagious and/or vaccine-resistant str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2451bb11a37471585b5495d4522cce99
https://doi.org/10.1101/2022.02.10.480009
https://doi.org/10.1101/2022.02.10.480009
Publikováno v:
PROCEEDING OF THE 1ST INTERNATIONAL CONFERENCE ON ADVANCED RESEARCH IN PURE AND APPLIED SCIENCE (ICARPAS2021): Third Annual Conference of Al-Muthanna University/College of Science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e83726cc19a8a59d1dfbaee48cc0cffe
https://doi.org/10.1063/5.0094140
https://doi.org/10.1063/5.0094140
Publikováno v:
AIP Conference Proceedings; 10/25/2022, Vol. 2398 Issue 1, p1-7, 7p