Zobrazeno 1 - 10 of 89 pro vyhledávání: '"Bagnolini G"'
1
Akademický článek
New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives.
Autor: Previtali V; Computational & Chemical Biology, Istituto Italiano di Tecnologia, 16163 Genova, Italy., Bagnolini G; Department of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy., Ciamarone A; Computational & Chemical Biology, Istituto Italiano di Tecnologia, 16163 Genova, Italy.; Department of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy., Ferrandi G; Computational & Chemical Biology, Istituto Italiano di Tecnologia, 16163 Genova, Italy.; Department of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy., Rinaldi F; Computational & Chemical Biology, Istituto Italiano di Tecnologia, 16163 Genova, Italy., Myers SH; Computational & Chemical Biology, Istituto Italiano di Tecnologia, 16163 Genova, Italy., Roberti M; Department of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy., Cavalli A; Computational & Chemical Biology, Istituto Italiano di Tecnologia, 16163 Genova, Italy.; Department of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2024 Jul 25; Vol. 67 (14), pp. 11488-11521. Date of Electronic Publication: 2024 Jul 02.
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2
Akademický článek
An 19 F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer.
Autor: Myers SH; Computational and Chemical Biology, Istituto Italiano di Tecnologia, 16163, Genoa, Italy., Poppi L; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Rinaldi F; Computational and Chemical Biology, Istituto Italiano di Tecnologia, 16163, Genoa, Italy; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Veronesi M; Structural Biophysics Facility, Istituto Italiano di Tecnologia, 16163, Genoa, Italy; D3 PharmaChemistry, Istituto Italiano di Tecnologia, 16163, Genoa, Italy., Ciamarone A; Computational and Chemical Biology, Istituto Italiano di Tecnologia, 16163, Genoa, Italy., Previtali V; Computational and Chemical Biology, Istituto Italiano di Tecnologia, 16163, Genoa, Italy., Bagnolini G; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Schipani F; Computational and Chemical Biology, Istituto Italiano di Tecnologia, 16163, Genoa, Italy., Ortega Martínez JA; Computational and Chemical Biology, Istituto Italiano di Tecnologia, 16163, Genoa, Italy., Girotto S; Computational and Chemical Biology, Istituto Italiano di Tecnologia, 16163, Genoa, Italy; Structural Biophysics Facility, Istituto Italiano di Tecnologia, 16163, Genoa, Italy., Di Stefano G; Department of Surgical and Medical Sciences, University of Bologna, 40126, Bologna, Italy., Farabegoli F; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Walsh N; School of Biotechnology, Dublin City University, D09 NR58, Dublin, Ireland., De Franco F; TES Pharma S.r.l., I-06073, Corciano, Perugia, Italy., Roberti M; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy. Electronic address: marinella.roberti@unibo.it., Cavalli A; Computational and Chemical Biology, Istituto Italiano di Tecnologia, 16163, Genoa, Italy; Swiss Federal Institute of Technology Lausanne (EPFL), Switzerland.
Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2024 Feb 05; Vol. 265, pp. 116114. Date of Electronic Publication: 2023 Dec 31.
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3
Akademický článek
Recognizing the power of machine learning and other computational methods to accelerate progress in small molecule targeting of RNA.
Autor: Bagnolini G; Department of Chemistry, Duke University, Durham, North Carolina 27708, USA., Luu TB; Department of Chemistry, Duke University, Durham, North Carolina 27708, USA., Hargrove AE; Department of Chemistry, Duke University, Durham, North Carolina 27708, USA amanda.hargrove@duke.edu.; Department of Biochemistry, Duke University School of Medicine, Durham, North Carolina 27710, USA.
Publikováno v: RNA (New York, N.Y.) [RNA] 2023 Apr; Vol. 29 (4), pp. 473-488. Date of Electronic Publication: 2023 Jan 24.
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4
Akademický článek
Identification of RAD51-BRCA2 Inhibitors Using N -Acylhydrazone-Based Dynamic Combinatorial Chemistry.
Autor: Bagnolini G; Computational & Chemical Biology (CCB), Istituto Italiano di Tecnologia (IIT), 16163 Genova, Italy.; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, 40126 Bologna, Italy.; Helmholtz Centre for Infection Research (HZI), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), 66123 Saarbrücken, Germany., Balboni B; Computational & Chemical Biology (CCB), Istituto Italiano di Tecnologia (IIT), 16163 Genova, Italy.; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, 40126 Bologna, Italy., Schipani F; Computational & Chemical Biology (CCB), Istituto Italiano di Tecnologia (IIT), 16163 Genova, Italy., Gioia D; Computational & Chemical Biology (CCB), Istituto Italiano di Tecnologia (IIT), 16163 Genova, Italy., Veronesi M; Structural Biophysics and Translational Pharmacology, Istituto Italiano di Tecnologia (IIT), 16163 Genova, Italy.; D3-PharmaChemistry, Istituto Italiano di Tecnologia (IIT), 16163 Genova, Italy., De Franco F; TES Pharma Srl, I-06073 Corciano, Perugia Italy., Kaya C; Helmholtz Centre for Infection Research (HZI), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), 66123 Saarbrücken, Germany.; Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany., Jumde RP; Helmholtz Centre for Infection Research (HZI), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), 66123 Saarbrücken, Germany., Ortega JA; Computational & Chemical Biology (CCB), Istituto Italiano di Tecnologia (IIT), 16163 Genova, Italy., Girotto S; Computational & Chemical Biology (CCB), Istituto Italiano di Tecnologia (IIT), 16163 Genova, Italy., Hirsch AKH; Helmholtz Centre for Infection Research (HZI), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), 66123 Saarbrücken, Germany.; Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany., Roberti M; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, 40126 Bologna, Italy., Cavalli A; Computational & Chemical Biology (CCB), Istituto Italiano di Tecnologia (IIT), 16163 Genova, Italy.; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, 40126 Bologna, Italy.
Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2022 Jul 28; Vol. 13 (8), pp. 1262-1269. Date of Electronic Publication: 2022 Jul 28 (Print Publication: 2022).
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5
Akademický článek
Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies.
Autor: Mazzei L; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.; Laboratory of Bioinorganic Chemistry, Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Giuseppe Fanin 40, 40127, Bologna, Italy., Contaldo U; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.; Laboratory of Chemistry and Biology of Metals, Université Grenoble Alpes, CEA, CNRS, 17 Avenue des Martyrs, 38000, Grenoble, France., Musiani F; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.; Laboratory of Bioinorganic Chemistry, Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Giuseppe Fanin 40, 40127, Bologna, Italy., Cianci M; Department of Agricultural, Food and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131, Ancona, Italy., Bagnolini G; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy., Roberti M; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy., Ciurli S; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.; Laboratory of Bioinorganic Chemistry, Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Giuseppe Fanin 40, 40127, Bologna, Italy.
Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Mar 08; Vol. 60 (11), pp. 6029-6035. Date of Electronic Publication: 2021 Feb 01.
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6
Biological and psychological predictors of posttraumatic stress disorder onset and chronicity. A one-year prospective study
Autor: Attal J, Bagnolini G, Marie-Laure Ancelin, Isabelle Chaudieu, Hermès A, Martrille L, Baccino E, Karen Ritchie, Jacqueline Scali, C. Gandubert, Isabelle Carrière, A.-M. Dupuy, Sebanne M
Publikováno v: Neurobiology of Stress
Neurobiology of Stress, 2016, 3, pp.61-67. 〈10.1016/j.ynstr.2016.02.002〉
Neurobiology of Stress, Elsevier, 2016, 3, pp.61-67. ⟨10.1016/j.ynstr.2016.02.002⟩
Neurobiology of Stress, Vol 3, Iss C, Pp 61-67 (2016)
Background Few studies have prospectively examined risk factors for posttraumatic stress disorder (PTSD) in the aftermath of a traumatic exposure. The aim of this study is to identify the concurrent influence of psychological and biological diatheses
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfee0241316e50694a197abb99a4c0b
https://pubmed.ncbi.nlm.nih.gov/27981178
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7
Akademický článek
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib.
Autor: Bagnolini G; Computational and Chemical Biology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.; Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy., Milano D; Computational and Chemical Biology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy., Manerba M; Computational and Chemical Biology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy., Schipani F; Computational and Chemical Biology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy., Ortega JA; Computational and Chemical Biology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy., Gioia D; Computational and Chemical Biology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy., Falchi F; Computational and Chemical Biology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy., Balboni A; Computational and Chemical Biology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.; Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy., Farabegoli F; Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy., De Franco F; TES Pharma S.r.l., Via Palmiro Togliatti 22bis, I-06073 Corciano, Perugia, Italy., Robertson J; TES Pharma S.r.l., Via Palmiro Togliatti 22bis, I-06073 Corciano, Perugia, Italy., Pellicciari R; TES Pharma S.r.l., Via Palmiro Togliatti 22bis, I-06073 Corciano, Perugia, Italy., Pallavicini I; Department of Experimental Oncology at the IEO, European Institute of Oncology IRCCS, IFOM-IEO Campus, Via Adamello 16, 20100 Milan, Italy., Peri S; Department of Experimental Oncology at the IEO, European Institute of Oncology IRCCS, IFOM-IEO Campus, Via Adamello 16, 20100 Milan, Italy., Minucci S; Department of Biosciences, University of Milan, Via Celoria 26, 20100 Milan, Italy.; Department of Experimental Oncology at the IEO, European Institute of Oncology IRCCS, IFOM-IEO Campus, Via Adamello 16, 20100 Milan, Italy., Girotto S; Computational and Chemical Biology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy., Di Stefano G; Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Via S. Giacomo 14, 40126 Bologna, Italy., Roberti M; Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy., Cavalli A; Computational and Chemical Biology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.; Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Mar 12; Vol. 63 (5), pp. 2588-2619. Date of Electronic Publication: 2020 Feb 24.
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8
Akademický článek
Rad51/BRCA2 disruptors inhibit homologous recombination and synergize with olaparib in pancreatic cancer cells.
Autor: Roberti M; Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy., Schipani F; Computational & Chemical Biology, Istituto Italiano di Tecnologia, via Morego 30, 16163, Genova, Italy., Bagnolini G; Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy; Computational & Chemical Biology, Istituto Italiano di Tecnologia, via Morego 30, 16163, Genova, Italy., Milano D; Computational & Chemical Biology, Istituto Italiano di Tecnologia, via Morego 30, 16163, Genova, Italy., Giacomini E; Computational & Chemical Biology, Istituto Italiano di Tecnologia, via Morego 30, 16163, Genova, Italy., Falchi F; Computational & Chemical Biology, Istituto Italiano di Tecnologia, via Morego 30, 16163, Genova, Italy., Balboni A; Computational & Chemical Biology, Istituto Italiano di Tecnologia, via Morego 30, 16163, Genova, Italy; Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Via S. Giacomo 14, 40126, Bologna, Italy., Manerba M; Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Via S. Giacomo 14, 40126, Bologna, Italy., Farabegoli F; Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy., De Franco F; TES Pharma S.r.l., Via Palmiro Togliatti 22bis, I-06073, Loc. Terrioli, Corciano, Perugia, Italy., Robertson J; TES Pharma S.r.l., Via Palmiro Togliatti 22bis, I-06073, Loc. Terrioli, Corciano, Perugia, Italy., Minucci S; Department of Experimental Oncology at the European Institute of Oncology, IFOM-IEO Campus, Via Adamello 16, 20100, Milan, Italy; Department of Biosciences, University of Milan, Via Celoria 26, 20100, Milan, Italy., Pallavicini I; Department of Experimental Oncology at the European Institute of Oncology, IFOM-IEO Campus, Via Adamello 16, 20100, Milan, Italy., Di Stefano G; Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Via S. Giacomo 14, 40126, Bologna, Italy., Girotto S; Computational & Chemical Biology, Istituto Italiano di Tecnologia, via Morego 30, 16163, Genova, Italy., Pellicciari R; TES Pharma S.r.l., Via Palmiro Togliatti 22bis, I-06073, Loc. Terrioli, Corciano, Perugia, Italy., Cavalli A; Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy; Computational & Chemical Biology, Istituto Italiano di Tecnologia, via Morego 30, 16163, Genova, Italy. Electronic address: andrea.cavalli@iit.it.
Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2019 Mar 01; Vol. 165, pp. 80-92. Date of Electronic Publication: 2019 Jan 10.
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9
Akademický článek
Locked Nucleic Acid Oligonucleotides Facilitate RNA•LNA-RNA Triple-Helix Formation and Reduce MALAT1 Levels.
Autor: Shivakumar, Krishna M.1 (AUTHOR) kshivaku@nd.edu, Mahendran, Gowthami1 (AUTHOR), Brown, Jessica A.1 (AUTHOR) jbrown33@nd.edu
Publikováno v: International Journal of Molecular Sciences. Feb2024, Vol. 25 Issue 3, p1630. 19p.
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10
Akademický článek
Butterfly Diversity in a Rapidly Developing Urban Area: A Case Study on a University Campus.
Autor: Fang, Sheng-Quan1,2 (AUTHOR) imclye@mail.ynu.edu.cn, Li, Yong-Ping3 (AUTHOR) liyp@ynu.edu.cn, Pan, Yue4,5 (AUTHOR) tangerinepan@163.com, Wang, Chong-Yun1,2 (AUTHOR) cywang@ynu.edu.cn, Peng, Ming-Chun1,2 (AUTHOR) mchpeng@ynu.edu.cn, Hu, Shao-Ji4,5 (AUTHOR) mchpeng@ynu.edu.cn
Publikováno v: Diversity (14242818). Jan2024, Vol. 16 Issue 1, p4. 20p.
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